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Items: 1 to 20 of 153

1.

Pharmaceutical modulation of canonical Wnt signaling in multipotent stromal cells for improved osteoinductive therapy.

Krause U, Harris S, Green A, Ylostalo J, Zeitouni S, Lee N, Gregory CA.

Proc Natl Acad Sci U S A. 2010 Mar 2;107(9):4147-52. doi: 10.1073/pnas.0914360107. Epub 2010 Feb 11.

2.

How Wnt signaling affects bone repair by mesenchymal stem cells from the bone marrow.

Gregory CA, Gunn WG, Reyes E, Smolarz AJ, Munoz J, Spees JL, Prockop DJ.

Ann N Y Acad Sci. 2005 May;1049:97-106. Review.

PMID:
15965110
3.

High throughput transcriptome profiling of lithium stimulated human mesenchymal stem cells reveals priming towards osteoblastic lineage.

Satija NK, Sharma D, Afrin F, Tripathi RP, Gangenahalli G.

PLoS One. 2013;8(1):e55769. doi: 10.1371/journal.pone.0055769. Epub 2013 Jan 30.

4.

FHL2 mediates dexamethasone-induced mesenchymal cell differentiation into osteoblasts by activating Wnt/beta-catenin signaling-dependent Runx2 expression.

Hamidouche Z, Haÿ E, Vaudin P, Charbord P, Schüle R, Marie PJ, Fromigué O.

FASEB J. 2008 Nov;22(11):3813-22. doi: 10.1096/fj.08-106302. Epub 2008 Jul 24.

5.

Baicalin, a flavone, induces the differentiation of cultured osteoblasts: an action via the Wnt/beta-catenin signaling pathway.

Guo AJ, Choi RC, Cheung AW, Chen VP, Xu SL, Dong TT, Chen JJ, Tsim KW.

J Biol Chem. 2011 Aug 12;286(32):27882-93. doi: 10.1074/jbc.M111.236281. Epub 2011 Jun 7. Erratum in: J Biol Chem. 2012 Feb 24;287(9):6958.

6.

Ethanol may suppress Wnt/beta-catenin signaling on human bone marrow stroma cells: a preliminary study.

Yeh CH, Chang JK, Wang YH, Ho ML, Wang GJ.

Clin Orthop Relat Res. 2008 May;466(5):1047-53. doi: 10.1007/s11999-008-0171-1. Epub 2008 Feb 21.

7.

Pharmaceutical inhibition of glycogen synthetase kinase-3β reduces multiple myeloma-induced bone disease in a novel murine plasmacytoma xenograft model.

Gunn WG, Krause U, Lee N, Gregory CA.

Blood. 2011 Feb 3;117(5):1641-51. doi: 10.1182/blood-2010-09-308171. Epub 2010 Dec 1.

8.

Glycogen synthase kinase-3α/β inhibition promotes in vivo amplification of endogenous mesenchymal progenitors with osteogenic and adipogenic potential and their differentiation to the osteogenic lineage.

Gambardella A, Nagaraju CK, O'Shea PJ, Mohanty ST, Kottam L, Pilling J, Sullivan M, Djerbi M, Koopmann W, Croucher PI, Bellantuono I.

J Bone Miner Res. 2011 Apr;26(4):811-21. doi: 10.1002/jbmr.266.

9.

Orally bioavailable GSK-3alpha/beta dual inhibitor increases markers of cellular differentiation in vitro and bone mass in vivo.

Kulkarni NH, Onyia JE, Zeng Q, Tian X, Liu M, Halladay DL, Frolik CA, Engler T, Wei T, Kriauciunas A, Martin TJ, Sato M, Bryant HU, Ma YL.

J Bone Miner Res. 2006 Jun;21(6):910-20.

10.

Lithium activates the Wnt and phosphatidylinositol 3-kinase Akt signaling pathways to promote cell survival in the absence of soluble survival factors.

Sinha D, Wang Z, Ruchalski KL, Levine JS, Krishnan S, Lieberthal W, Schwartz JH, Borkan SC.

Am J Physiol Renal Physiol. 2005 Apr;288(4):F703-13. Epub 2004 Nov 30.

11.

Inhibition of glycogen synthase kinase-3beta attenuates glucocorticoid-induced bone loss.

Wang FS, Ko JY, Weng LH, Yeh DW, Ke HJ, Wu SL.

Life Sci. 2009 Nov 4;85(19-20):685-92. doi: 10.1016/j.lfs.2009.09.009. Epub 2009 Sep 25.

PMID:
19782693
12.

The promise of canonical Wnt signaling modulators in enhancing bone repair.

Gregory CA, Green A, Lee N, Rao A, Gunn W.

Drug News Perspect. 2006 Oct;19(8):445-52. Review.

PMID:
17160144
13.

Wnt-dependent osteogenic commitment of bone marrow stromal cells using a novel GSK3β inhibitor.

Cook DA, Fellgett SW, Pownall ME, O'Shea PJ, Genever PG.

Stem Cell Res. 2014 Mar;12(2):415-27. doi: 10.1016/j.scr.2013.10.002. Epub 2013 Oct 16.

14.

Differentiation-inducing factor-1 alters canonical Wnt signaling and suppresses alkaline phosphatase expression in osteoblast-like cell lines.

Matsuzaki E, Takahashi-Yanaga F, Miwa Y, Hirata M, Watanabe Y, Sato N, Morimoto S, Hirofuji T, Maeda K, Sasaguri T.

J Bone Miner Res. 2006 Aug;21(8):1307-16.

15.

Fluoride promotes osteoblastic differentiation through canonical Wnt/β-catenin signaling pathway.

Pan L, Shi X, Liu S, Guo X, Zhao M, Cai R, Sun G.

Toxicol Lett. 2014 Feb 10;225(1):34-42. doi: 10.1016/j.toxlet.2013.11.029. Epub 2013 Dec 1.

PMID:
24300170
16.

Activation of non-canonical Wnt/JNK pathway by Wnt3a is associated with differentiation fate determination of human bone marrow stromal (mesenchymal) stem cells.

Qiu W, Chen L, Kassem M.

Biochem Biophys Res Commun. 2011 Sep 16;413(1):98-104. doi: 10.1016/j.bbrc.2011.08.061. Epub 2011 Aug 22.

PMID:
21875572
18.

Dkk1-induced inhibition of Wnt signaling in osteoblast differentiation is an underlying mechanism of bone loss in multiple myeloma.

Qiang YW, Barlogie B, Rudikoff S, Shaughnessy JD Jr.

Bone. 2008 Apr;42(4):669-80. doi: 10.1016/j.bone.2007.12.006. Epub 2007 Dec 27.

PMID:
18294945
19.

Epimedium-derived flavonoids modulate the balance between osteogenic differentiation and adipogenic differentiation in bone marrow stromal cells of ovariectomized rats via Wnt/β-catenin signal pathway activation.

Xu YX, Wu CL, Wu Y, Tong PJ, Jin HT, Yu NZ, Xiao LW.

Chin J Integr Med. 2012 Dec;18(12):909-17. doi: 10.1007/s11655-012-1294-2. Epub 2012 Dec 13.

PMID:
23238999
20.

Reciprocal interferences of TNF-α and Wnt1/β-catenin signaling axes shift bone marrow-derived stem cells towards osteoblast lineage after ethanol exposure.

Chen Y, Chen L, Yin Q, Gao H, Dong P, Zhang X, Kang J.

Cell Physiol Biochem. 2013;32(3):755-65. doi: 10.1159/000354477. Epub 2013 Sep 13.

PMID:
24080828
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