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Results: 1 to 20 of 96

1.

Signaling via Alk5 controls the ontogeny of lung Clara cells.

Xing Y, Li C, Li A, Sridurongrit S, Tiozzo C, Bellusci S, Borok Z, Kaartinen V, Minoo P.

Development. 2010 Mar;137(5):825-33. doi: 10.1242/dev.040535.

PMID:
20147383
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Alk5-mediated transforming growth factor β signaling acts upstream of fibroblast growth factor 10 to regulate the proliferation and maintenance of dental epithelial stem cells.

Zhao H, Li S, Han D, Kaartinen V, Chai Y.

Mol Cell Biol. 2011 May;31(10):2079-89. doi: 10.1128/MCB.01439-10. Epub 2011 Mar 14.

PMID:
21402782
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Critical roles of the TGF-beta type I receptor ALK5 in perichondrial formation and function, cartilage integrity, and osteoblast differentiation during growth plate development.

Matsunobu T, Torigoe K, Ishikawa M, de Vega S, Kulkarni AB, Iwamoto Y, Yamada Y.

Dev Biol. 2009 Aug 15;332(2):325-38. doi: 10.1016/j.ydbio.2009.06.002. Epub 2009 Jun 6.

PMID:
19501582
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Tissue-dependent consequences of Apc inactivation on proliferation and differentiation of ciliated cell progenitors via Wnt and notch signaling.

Li A, Chan B, Felix JC, Xing Y, Li M, Brody SL, Borok Z, Li C, Minoo P.

PLoS One. 2013 Apr 30;8(4):e62215. doi: 10.1371/journal.pone.0062215. Print 2013.

PMID:
23646120
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Compensatory signalling induced in the yolk sac vasculature by deletion of TGFbeta receptors in mice.

Carvalho RL, Itoh F, Goumans MJ, Lebrin F, Kato M, Takahashi S, Ema M, Itoh S, van Rooijen M, Bertolino P, Ten Dijke P, Mummery CL.

J Cell Sci. 2007 Dec 15;120(Pt 24):4269-77. Epub 2007 Nov 20.

PMID:
18029401
[PubMed - indexed for MEDLINE]
Free Article
6.

Signaling via the Tgf-beta type I receptor Alk5 in heart development.

Sridurongrit S, Larsson J, Schwartz R, Ruiz-Lozano P, Kaartinen V.

Dev Biol. 2008 Oct 1;322(1):208-18. doi: 10.1016/j.ydbio.2008.07.038. Epub 2008 Aug 7.

PMID:
18718461
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Different assemblies of Notch receptors coordinate the distribution of the major bronchial Clara, ciliated and neuroendocrine cells.

Morimoto M, Nishinakamura R, Saga Y, Kopan R.

Development. 2012 Dec 1;139(23):4365-73. doi: 10.1242/dev.083840.

PMID:
23132245
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Poor vessel formation in embryos from knock-in mice expressing ALK5 with L45 loop mutation defective in Smad activation.

Itoh F, Itoh S, Carvalho RL, Adachi T, Ema M, Goumans MJ, Larsson J, Karlsson S, Takahashi S, Mummery CL, Dijke PT, Kato M.

Lab Invest. 2009 Jul;89(7):800-10. doi: 10.1038/labinvest.2009.37. Epub 2009 Apr 27.

PMID:
19398960
[PubMed - indexed for MEDLINE]
Free Article
9.

Bmp signaling regulates proximal-distal differentiation of endoderm in mouse lung development.

Weaver M, Yingling JM, Dunn NR, Bellusci S, Hogan BL.

Development. 1999 Sep;126(18):4005-15.

PMID:
10457010
[PubMed - indexed for MEDLINE]
Free Article
10.

Mechanisms of TGFbeta inhibition of LUNG endodermal morphogenesis: the role of TbetaRII, Smads, Nkx2.1 and Pten.

Xing Y, Li C, Hu L, Tiozzo C, Li M, Chai Y, Bellusci S, Anderson S, Minoo P.

Dev Biol. 2008 Aug 15;320(2):340-50. doi: 10.1016/j.ydbio.2008.04.044. Epub 2008 May 13.

PMID:
18602626
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

NOTCH1 is required for regeneration of Clara cells during repair of airway injury.

Xing Y, Li A, Borok Z, Li C, Minoo P.

Stem Cells. 2012 May;30(5):946-55. doi: 10.1002/stem.1059. Erratum in: Stem Cells. 2012 Jul;30(7):1579.

PMID:
22331706
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Notch signaling controls the balance of ciliated and secretory cell fates in developing airways.

Tsao PN, Vasconcelos M, Izvolsky KI, Qian J, Lu J, Cardoso WV.

Development. 2009 Jul;136(13):2297-307. doi: 10.1242/dev.034884.

PMID:
19502490
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Gene expression profiling demonstrates that TGF-beta1 signals exclusively through receptor complexes involving Alk5 and identifies targets of TGF-beta signaling.

Karlsson G, Liu Y, Larsson J, Goumans MJ, Lee JS, Thorgeirsson SS, Ringnér M, Karlsson S.

Physiol Genomics. 2005 May 11;21(3):396-403. Epub 2005 Mar 15.

PMID:
15769904
[PubMed - indexed for MEDLINE]
Free Article
14.

ALK5 phosphorylation of the endoglin cytoplasmic domain regulates Smad1/5/8 signaling and endothelial cell migration.

Ray BN, Lee NY, How T, Blobe GC.

Carcinogenesis. 2010 Mar;31(3):435-41. doi: 10.1093/carcin/bgp327. Epub 2009 Dec 30.

PMID:
20042635
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Elf3 plays a role in regulating bronchiolar epithelial repair kinetics following Clara cell-specific injury.

Oliver JR, Kushwah R, Wu J, Pan J, Cutz E, Yeger H, Waddell TK, Hu J.

Lab Invest. 2011 Oct;91(10):1514-29. doi: 10.1038/labinvest.2011.100. Epub 2011 Jun 27.

PMID:
21709667
[PubMed - indexed for MEDLINE]
Free Article
16.

ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2.

Park SO, Lee YJ, Seki T, Hong KH, Fliess N, Jiang Z, Park A, Wu X, Kaartinen V, Roman BL, Oh SP.

Blood. 2008 Jan 15;111(2):633-42. Epub 2007 Oct 2.

PMID:
17911384
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Sox2 is required for maintenance and differentiation of bronchiolar Clara, ciliated, and goblet cells.

Tompkins DH, Besnard V, Lange AW, Wert SE, Keiser AR, Smith AN, Lang R, Whitsett JA.

PLoS One. 2009 Dec 14;4(12):e8248. doi: 10.1371/journal.pone.0008248.

PMID:
20011520
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

ALK1 opposes ALK5/Smad3 signaling and expression of extracellular matrix components in human chondrocytes.

Finnson KW, Parker WL, ten Dijke P, Thorikay M, Philip A.

J Bone Miner Res. 2008 Jun;23(6):896-906. doi: 10.1359/jbmr.080209.

PMID:
18333754
[PubMed - indexed for MEDLINE]
19.

TGFbeta-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFbeta switch.

Liu IM, Schilling SH, Knouse KA, Choy L, Derynck R, Wang XF.

EMBO J. 2009 Jan 21;28(2):88-98. doi: 10.1038/emboj.2008.266. Epub 2008 Dec 18.

PMID:
19096363
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration.

Zhang Y, Goss AM, Cohen ED, Kadzik R, Lepore JJ, Muthukumaraswamy K, Yang J, DeMayo FJ, Whitsett JA, Parmacek MS, Morrisey EE.

Nat Genet. 2008 Jul;40(7):862-70. doi: 10.1038/ng.157. Epub 2008 Jun 8.

PMID:
18536717
[PubMed - indexed for MEDLINE]
Free PMC Article

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