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Items: 1 to 20 of 96

1.

Technosphere insulin: defining the role of Technosphere particles at the cellular level.

Angelo R, Rousseau K, Grant M, Leone-Bay A, Richardson P.

J Diabetes Sci Technol. 2009 May 1;3(3):545-54.

2.

Insulin lung deposition and clearance following Technosphere® insulin inhalation powder administration.

Cassidy JP, Amin N, Marino M, Gotfried M, Meyer T, Sommerer K, Baughman RA.

Pharm Res. 2011 Sep;28(9):2157-64. doi: 10.1007/s11095-011-0443-4. Epub 2011 Apr 14.

PMID:
21491144
3.

Technosphere/Insulin--proof of concept study with a new insulin formulation for pulmonary delivery.

Steiner S, Pfützner A, Wilson BR, Harzer O, Heinemann L, Rave K.

Exp Clin Endocrinol Diabetes. 2002 Jan;110(1):17-21.

PMID:
11835120
4.

Sodium caprate as an enhancer of macromolecule permeation across tricellular tight junctions of intestinal cells.

Krug SM, Amasheh M, Dittmann I, Christoffel I, Fromm M, Amasheh S.

Biomaterials. 2013 Jan;34(1):275-82. doi: 10.1016/j.biomaterials.2012.09.051. Epub 2012 Oct 12.

PMID:
23069717
5.

Disruption of the F-actin cytoskeleton and monolayer barrier integrity induced by PAF and the protective effect of ITF on intestinal epithelium.

Xu LF, Xu C, Mao ZQ, Teng X, Ma L, Sun M.

Arch Pharm Res. 2011 Feb;34(2):245-51. doi: 10.1007/s12272-011-0210-4. Epub 2011 Mar 6.

PMID:
21380808
6.

A review of inhaled technosphere insulin.

Neumiller JJ, Campbell RK, Wood LD.

Ann Pharmacother. 2010 Jul-Aug;44(7-8):1231-9. doi: 10.1345/aph.1P055. Epub 2010 Jun 1. Review.

PMID:
20516362
7.

Sodium caprate transiently opens claudin-5-containing barriers at tight junctions of epithelial and endothelial cells.

Del Vecchio G, Tscheik C, Tenz K, Helms HC, Winkler L, Blasig R, Blasig IE.

Mol Pharm. 2012 Sep 4;9(9):2523-33. doi: 10.1021/mp3001414. Epub 2012 Aug 21.

PMID:
22827574
9.

Absorption enhancement, structural changes in tight junctions and cytotoxicity caused by palmitoyl carnitine in Caco-2 and IEC-18 cells.

Duizer E, van der Wulp C, Versantvoort CH, Groten JP.

J Pharmacol Exp Ther. 1998 Oct;287(1):395-402.

10.

Mechanisms for absorption enhancement of inhaled insulin by sodium taurocholate.

Johansson F, Hjertberg E, Eirefelt S, Tronde A, Hultkvist Bengtsson U.

Eur J Pharm Sci. 2002 Oct;17(1-2):63-71.

PMID:
12356421
11.

Pulmonary insulin delivery by means of the Technosphere drug carrier mechanism.

Pfützner A, Forst T.

Expert Opin Drug Deliv. 2005 Nov;2(6):1097-106.

PMID:
16296812
12.

Inspiratory efforts achieved in use of the Technosphere insulin inhalation system.

Smutney CC, Friedman EM, Polidoro JM, Amin N.

J Diabetes Sci Technol. 2009 Sep 1;3(5):1175-82.

13.

The transient increase of tight junction permeability induced by bryostatin 1 correlates with rapid downregulation of protein kinase C-alpha.

Clarke H, Ginanni N, Laughlin KV, Smith JB, Pettit GR, Mullin JM.

Exp Cell Res. 2000 Nov 25;261(1):239-49.

PMID:
11082294
14.

Transepithelial electrical resistance is not a reliable measurement of the Caco-2 monolayer integrity in Transwell.

Mukherjee T, Squillantea E, Gillespieb M, Shao J.

Drug Deliv. 2004 Jan-Feb;11(1):11-8.

PMID:
15168786
15.
16.

Technosphere insulin: an inhaled prandial insulin product.

Neumiller JJ, Campbell RK.

BioDrugs. 2010 Jun;24(3):165-72. doi: 10.2165/11536700-000000000-00000. Review.

PMID:
20462282
17.

Randomized forced titration to different doses of technosphere insulin demonstrates reduction in postprandial glucose excursions and hemoglobin A1c in patients with type 2 diabetes.

Tack CJ, Christov V, de Galan BE, Derwahl KM, Klausmann G, Pelikánová T, Perusicová J, Boss AH, Amin N, Kramer D, Petrucci R, Yu W; 005 Study Group.

J Diabetes Sci Technol. 2008 Jan;2(1):47-57.

18.
19.

Efficacy and safety of Technosphere inhaled insulin compared with Technosphere powder placebo in insulin-naive type 2 diabetes suboptimally controlled with oral agents.

Rosenstock J, Bergenstal R, Defronzo RA, Hirsch IB, Klonoff D, Boss AH, Kramer D, Petrucci R, Yu W, Levy B; 0008 Study Group.

Diabetes Care. 2008 Nov;31(11):2177-82. doi: 10.2337/dc08-0315. Epub 2008 Aug 4.

20.

Evaluation of dodecylmaltoside as a permeability enhancer for insulin using human carcinoma cells.

Tirumalasetty PP, Eley JG.

J Pharm Sci. 2005 Feb;94(2):246-55.

PMID:
15570604
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