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Items: 1 to 20 of 97

1.

HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species.

Capasso M, Bhamrah MK, Henley T, Boyd RS, Langlais C, Cain K, Dinsdale D, Pulford K, Khan M, Musset B, Cherny VV, Morgan D, Gascoyne RD, Vigorito E, DeCoursey TE, MacLennan IC, Dyer MJ.

Nat Immunol. 2010 Mar;11(3):265-72. doi: 10.1038/ni.1843. Epub 2010 Feb 7.

2.

Syk and Bruton's tyrosine kinase are required for B cell antigen receptor-mediated activation of the kinase Akt.

Craxton A, Jiang A, Kurosaki T, Clark EA.

J Biol Chem. 1999 Oct 22;274(43):30644-50.

3.

The BAFF receptor transduces survival signals by co-opting the B cell receptor signaling pathway.

Schweighoffer E, Vanes L, Nys J, Cantrell D, McCleary S, Smithers N, Tybulewicz VL.

Immunity. 2013 Mar 21;38(3):475-88. doi: 10.1016/j.immuni.2012.11.015. Epub 2013 Feb 28.

4.

The tyrosine kinases Syk and Lyn exert opposing effects on the activation of protein kinase Akt/PKB in B lymphocytes.

Li HL, Davis WW, Whiteman EL, Birnbaum MJ, Puré E.

Proc Natl Acad Sci U S A. 1999 Jun 8;96(12):6890-5.

5.

CD19 amplifies B lymphocyte signal transduction by regulating Src-family protein tyrosine kinase activation.

Fujimoto M, Poe JC, Jansen PJ, Sato S, Tedder TF.

J Immunol. 1999 Jun 15;162(12):7088-94.

6.

Enhanced activation of an amino-terminally truncated isoform of the voltage-gated proton channel HVCN1 enriched in malignant B cells.

Hondares E, Brown MA, Musset B, Morgan D, Cherny VV, Taubert C, Bhamrah MK, Coe D, Marelli-Berg F, Gribben JG, Dyer MJ, DeCoursey TE, Capasso M.

Proc Natl Acad Sci U S A. 2014 Dec 16;111(50):18078-83. doi: 10.1073/pnas.1411390111. Epub 2014 Nov 25.

7.

B cell antigen receptor-induced activation of Akt promotes B cell survival and is dependent on Syk kinase.

Pogue SL, Kurosaki T, Bolen J, Herbst R.

J Immunol. 2000 Aug 1;165(3):1300-6.

8.

Prolonged production of reactive oxygen species in response to B cell receptor stimulation promotes B cell activation and proliferation.

Wheeler ML, Defranco AL.

J Immunol. 2012 Nov 1;189(9):4405-16. doi: 10.4049/jimmunol.1201433. Epub 2012 Sep 28.

9.

The Syk-binding ubiquitin ligase c-Cbl mediates signaling-dependent B cell receptor ubiquitination and B cell receptor-mediated antigen processing and presentation.

Katkere B, Rosa S, Drake JR.

J Biol Chem. 2012 May 11;287(20):16636-44. doi: 10.1074/jbc.M112.357640. Epub 2012 Mar 27.

11.

Swiprosin-1/EFhd2 controls B cell receptor signaling through the assembly of the B cell receptor, Syk, and phospholipase C gamma2 in membrane rafts.

Kroczek C, Lang C, Brachs S, Grohmann M, Dütting S, Schweizer A, Nitschke L, Feller SM, Jäck HM, Mielenz D.

J Immunol. 2010 Apr 1;184(7):3665-76. doi: 10.4049/jimmunol.0903642. Epub 2010 Mar 1.

13.

The B cell antigen receptor activates the Akt (protein kinase B)/glycogen synthase kinase-3 signaling pathway via phosphatidylinositol 3-kinase.

Gold MR, Scheid MP, Santos L, Dang-Lawson M, Roth RA, Matsuuchi L, Duronio V, Krebs DL.

J Immunol. 1999 Aug 15;163(4):1894-905.

15.
16.

Activation of the Syk tyrosine kinase is insufficient for downstream signal transduction in B lymphocytes.

Hsueh RC, Hammill AM, Lee JA, Uhr JW, Scheuermann RH.

BMC Immunol. 2002 Dec 6;3:16. Epub 2002 Dec 6.

17.

Autoinhibition and adapter function of Syk.

Kulathu Y, Grothe G, Reth M.

Immunol Rev. 2009 Nov;232(1):286-99. doi: 10.1111/j.1600-065X.2009.00837.x. Review.

PMID:
19909371
19.

Syk mediates BCR- and CD40-signaling integration during B cell activation.

Ying H, Li Z, Yang L, Zhang J.

Immunobiology. 2011 May;216(5):566-70. doi: 10.1016/j.imbio.2010.09.016. Epub 2010 Oct 7.

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