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Results: 1 to 20 of 93

1.

The histone demethylase UTX enables RB-dependent cell fate control.

Wang JK, Tsai MC, Poulin G, Adler AS, Chen S, Liu H, Shi Y, Chang HY.

Genes Dev. 2010 Feb 15;24(4):327-32. doi: 10.1101/gad.1882610. Epub 2010 Feb 1.

PMID:
20123895
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The C. elegans H3K27 demethylase UTX-1 is essential for normal development, independent of its enzymatic activity.

Vandamme J, Lettier G, Sidoli S, Di Schiavi E, Nørregaard Jensen O, Salcini AE.

PLoS Genet. 2012;8(5):e1002647. doi: 10.1371/journal.pgen.1002647. Epub 2012 May 3.

PMID:
22570628
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development.

Agger K, Cloos PA, Christensen J, Pasini D, Rose S, Rappsilber J, Issaeva I, Canaani E, Salcini AE, Helin K.

Nature. 2007 Oct 11;449(7163):731-4. Epub 2007 Aug 22.

PMID:
17713478
[PubMed - indexed for MEDLINE]
4.

The H3K27 demethylase UTX-1 regulates C. elegans lifespan in a germline-independent, insulin-dependent manner.

Maures TJ, Greer EL, Hauswirth AG, Brunet A.

Aging Cell. 2011 Dec;10(6):980-90. doi: 10.1111/j.1474-9726.2011.00738.x. Epub 2011 Sep 16.

PMID:
21834846
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Utx is required for proper induction of ectoderm and mesoderm during differentiation of embryonic stem cells.

Morales Torres C, Laugesen A, Helin K.

PLoS One. 2013;8(4):e60020. doi: 10.1371/journal.pone.0060020. Epub 2013 Apr 3.

PMID:
23573229
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Tumor suppression by the histone demethylase UTX.

Tsai MC, Wang JK, Chang HY.

Cell Cycle. 2010 Jun 1;9(11):2043-4. Epub 2010 Jun 1. No abstract available.

PMID:
20505331
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The tumor suppressor Rb and its related Rbl2 genes are regulated by Utx histone demethylase.

Terashima M, Ishimura A, Yoshida M, Suzuki Y, Sugano S, Suzuki T.

Biochem Biophys Res Commun. 2010 Aug 20;399(2):238-44. doi: 10.1016/j.bbrc.2010.07.061. Epub 2010 Jul 30.

PMID:
20650264
[PubMed - indexed for MEDLINE]
8.

A histone H3 lysine 27 demethylase regulates animal posterior development.

Lan F, Bayliss PE, Rinn JL, Whetstine JR, Wang JK, Chen S, Iwase S, Alpatov R, Issaeva I, Canaani E, Roberts TM, Chang HY, Shi Y.

Nature. 2007 Oct 11;449(7163):689-94. Epub 2007 Sep 12.

PMID:
17851529
[PubMed - indexed for MEDLINE]
9.

UTX regulates mesoderm differentiation of embryonic stem cells independent of H3K27 demethylase activity.

Wang C, Lee JE, Cho YW, Xiao Y, Jin Q, Liu C, Ge K.

Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15324-9. Epub 2012 Sep 4.

PMID:
22949634
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases.

Hong S, Cho YW, Yu LR, Yu H, Veenstra TD, Ge K.

Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18439-44. Epub 2007 Nov 14.

PMID:
18003914
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

UTX and MLL4 coordinately regulate transcriptional programs for cell proliferation and invasiveness in breast cancer cells.

Kim JH, Sharma A, Dhar SS, Lee SH, Gu B, Chan CH, Lin HK, Lee MG.

Cancer Res. 2014 Mar 15;74(6):1705-17. doi: 10.1158/0008-5472.CAN-13-1896. Epub 2014 Feb 3.

PMID:
24491801
[PubMed - indexed for MEDLINE]
12.

Expression and significance of histone H3K27 demethylases in renal cell carcinoma.

Shen Y, Guo X, Wang Y, Qiu W, Chang Y, Zhang A, Duan X.

BMC Cancer. 2012 Oct 12;12:470. doi: 10.1186/1471-2407-12-470.

PMID:
23057811
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Role of H3K27 demethylases Jmjd3 and UTX in transcriptional regulation.

Hübner MR, Spector DL.

Cold Spring Harb Symp Quant Biol. 2010;75:43-9. doi: 10.1101/sqb.2010.75.020. Epub 2011 Jan 5.

PMID:
21209387
[PubMed - indexed for MEDLINE]
14.

Depletion of histone demethylase KDM2A inhibited cell proliferation of stem cells from apical papilla by de-repression of p15INK4B and p27Kip1.

Gao R, Dong R, Du J, Ma P, Wang S, Fan Z.

Mol Cell Biochem. 2013 Jul;379(1-2):115-22. doi: 10.1007/s11010-013-1633-7. Epub 2013 Apr 5.

PMID:
23559091
[PubMed - indexed for MEDLINE]
15.

UTX and UTY demonstrate histone demethylase-independent function in mouse embryonic development.

Shpargel KB, Sengoku T, Yokoyama S, Magnuson T.

PLoS Genet. 2012 Sep;8(9):e1002964. doi: 10.1371/journal.pgen.1002964. Epub 2012 Sep 27.

PMID:
23028370
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner.

Welstead GG, Creyghton MP, Bilodeau S, Cheng AW, Markoulaki S, Young RA, Jaenisch R.

Proc Natl Acad Sci U S A. 2012 Aug 7;109(32):13004-9. doi: 10.1073/pnas.1210787109. Epub 2012 Jul 23.

PMID:
22826230
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

HTZ-1/H2A.z and MYS-1/MYST HAT act redundantly to maintain cell fates in somatic gonadal cells through repression of ceh-22 in C. elegans.

Shibata Y, Sawa H, Nishiwaki K.

Development. 2014 Jan;141(1):209-18. doi: 10.1242/dev.090746.

PMID:
24346701
[PubMed - indexed for MEDLINE]
Free Article
18.

Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases.

Whetstine JR, Nottke A, Lan F, Huarte M, Smolikov S, Chen Z, Spooner E, Li E, Zhang G, Colaiacovo M, Shi Y.

Cell. 2006 May 5;125(3):467-81. Epub 2006 Apr 6.

PMID:
16603238
[PubMed - indexed for MEDLINE]
Free Article
19.

Nicotine induces alteration of H3K27 demethylase UTX in kidney cancer cell.

Guo X, Li X, Wang Y, Tian Z, Duan X, Cai Z.

Hum Exp Toxicol. 2014 Mar;33(3):264-9. doi: 10.1177/0960327113499043. Epub 2013 Aug 7.

PMID:
23925944
[PubMed - indexed for MEDLINE]
20.

KSHV PAN RNA associates with demethylases UTX and JMJD3 to activate lytic replication through a physical interaction with the virus genome.

Rossetto CC, Pari G.

PLoS Pathog. 2012;8(5):e1002680. doi: 10.1371/journal.ppat.1002680. Epub 2012 May 10.

PMID:
22589717
[PubMed - indexed for MEDLINE]
Free PMC Article
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