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Results: 1 to 20 of 109

1.

Immunogenicity of whole-parasite vaccines against Plasmodium falciparum involves malarial hemozoin and host TLR9.

Coban C, Igari Y, Yagi M, Reimer T, Koyama S, Aoshi T, Ohata K, Tsukui T, Takeshita F, Sakurai K, Ikegami T, Nakagawa A, Horii T, Nuñez G, Ishii KJ, Akira S.

Cell Host Microbe. 2010 Jan 21;7(1):50-61. doi: 10.1016/j.chom.2009.12.003.

PMID:
20114028
[PubMed - indexed for MEDLINE]
Free Article
2.

Hemozoin: malaria's "built-in" adjuvant and TLR9 agonist.

Wagner H.

Cell Host Microbe. 2010 Jan 21;7(1):5-6. doi: 10.1016/j.chom.2010.01.002.

PMID:
20114022
[PubMed - indexed for MEDLINE]
Free Article
3.

TLR9 and endogenous adjuvants of the whole blood-stage malaria vaccine.

Coban C, Horii T, Akira S, Ishii KJ.

Expert Rev Vaccines. 2010 Jul;9(7):775-84. doi: 10.1586/erv.10.60. Review.

PMID:
20624050
[PubMed - indexed for MEDLINE]
4.

Malaria hemozoin is immunologically inert but radically enhances innate responses by presenting malaria DNA to Toll-like receptor 9.

Parroche P, Lauw FN, Goutagny N, Latz E, Monks BG, Visintin A, Halmen KA, Lamphier M, Olivier M, Bartholomeu DC, Gazzinelli RT, Golenbock DT.

Proc Natl Acad Sci U S A. 2007 Feb 6;104(6):1919-24. Epub 2007 Jan 29.

PMID:
17261807
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Immunogenicity of a recombinant malaria vaccine candidate, domain I+II of AMA-1 ectodomain, from Indian P. falciparum alleles.

Lalitha PV, Biswas S, Pillai CR, Saxena RK.

Vaccine. 2008 Aug 18;26(35):4526-35. doi: 10.1016/j.vaccine.2008.06.031. Epub 2008 Jun 30.

PMID:
18590786
[PubMed - indexed for MEDLINE]
6.

Protein-DNA complex is the exclusive malaria parasite component that activates dendritic cells and triggers innate immune responses.

Wu X, Gowda NM, Kumar S, Gowda DC.

J Immunol. 2010 Apr 15;184(8):4338-48. doi: 10.4049/jimmunol.0903824. Epub 2010 Mar 15.

PMID:
20231693
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Enhanced immunogenicity of Plasmodium falciparum peptide vaccines using a topical adjuvant containing a potent synthetic Toll-like receptor 7 agonist, imiquimod.

Othoro C, Johnston D, Lee R, Soverow J, Bystryn JC, Nardin E.

Infect Immun. 2009 Feb;77(2):739-48. doi: 10.1128/IAI.00974-08. Epub 2008 Dec 1.

PMID:
19047411
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Pure Hemozoin is inflammatory in vivo and activates the NALP3 inflammasome via release of uric acid.

Griffith JW, Sun T, McIntosh MT, Bucala R.

J Immunol. 2009 Oct 15;183(8):5208-20. doi: 10.4049/jimmunol.0713552. Epub 2009 Sep 25.

PMID:
19783673
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Toll-like receptor 9 mediates innate immune activation by the malaria pigment hemozoin.

Coban C, Ishii KJ, Kawai T, Hemmi H, Sato S, Uematsu S, Yamamoto M, Takeuchi O, Itagaki S, Kumar N, Horii T, Akira S.

J Exp Med. 2005 Jan 3;201(1):19-25.

PMID:
15630134
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Biological activities of anti-merozoite surface protein-1 antibodies induced by adjuvant-assisted immunizations in mice with different immune gene knockouts.

Hui G, Choe D, Hashimoto C.

Clin Vaccine Immunol. 2008 Aug;15(8):1145-50. doi: 10.1128/CVI.00058-08. Epub 2008 Jun 18.

PMID:
18562564
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Preclinical evaluation of the safety and immunogenicity of a vaccine consisting of Plasmodium falciparum liver-stage antigen 1 with adjuvant AS01B administered alone or concurrently with the RTS,S/AS01B vaccine in rhesus primates.

Pichyangkul S, Kum-Arb U, Yongvanitchit K, Limsalakpetch A, Gettayacamin M, Lanar DE, Ware LA, Stewart VA, Heppner DG, Mettens P, Cohen JD, Ballou WR, Fukuda MM.

Infect Immun. 2008 Jan;76(1):229-38. Epub 2007 Oct 22.

PMID:
17954725
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Plasmodium falciparum polyoximes: highly immunogenic synthetic vaccines constructed by chemoselective ligation of repeat B-cell epitopes and a universal T-cell epitope of CS protein.

Nardin EH, Calvo-Calle JM, Oliveira GA, Clavijo P, Nussenzweig R, Simon R, Zeng W, Rose K.

Vaccine. 1998 Apr;16(6):590-600.

PMID:
9569470
[PubMed - indexed for MEDLINE]
14.

Immunogenicity of Plasmodium falciparum and Plasmodium vivax circumsporozoite protein repeat multiple antigen constructs (MAC).

Udhayakumar V, Saekhou A, Fang S, Jue D, Wohlhueter RM, Lal AA.

Vaccine. 1998 May-Jun;16(9-10):982-8.

PMID:
9682348
[PubMed - indexed for MEDLINE]
15.

Efficient immunization and cross-priming by vaccine adjuvants containing TLR3 or TLR9 agonists complexed to cationic liposomes.

Zaks K, Jordan M, Guth A, Sellins K, Kedl R, Izzo A, Bosio C, Dow S.

J Immunol. 2006 Jun 15;176(12):7335-45.

PMID:
16751377
[PubMed - indexed for MEDLINE]
Free Article
16.

Lipopeptide immunization without adjuvant induces potent and long-lasting B, T helper, and cytotoxic T lymphocyte responses against a malaria liver stage antigen in mice and chimpanzees.

BenMohamed L, Gras-Masse H, Tartar A, Daubersies P, Brahimi K, Bossus M, Thomas A, Druilhe P.

Eur J Immunol. 1997 May;27(5):1242-53.

PMID:
9174617
[PubMed - indexed for MEDLINE]
17.

Immunogenicity of the Plasmodium falciparum Pf332-DBL domain in combination with different adjuvants.

Du C, Nilsson S, Lu H, Yin J, Jiang N, Wahlgren M, Chen Q.

Vaccine. 2010 Jul 12;28(31):4977-83.

PMID:
20653104
[PubMed - indexed for MEDLINE]
18.

The TLR9 agonist CpG fails to enhance the acquisition of Plasmodium falciparum-specific memory B cells in semi-immune adults in Mali.

Traore B, Koné Y, Doumbo S, Doumtabé D, Traoré A, Crompton PD, Mircetic M, Huang CY, Kayentao K, Dicko A, Sagara I, Ellis RD, Miura K, Guindo A, Miller LH, Doumbo OK, Pierce SK.

Vaccine. 2009 Dec 9;27(52):7299-303. doi: 10.1016/j.vaccine.2009.08.023. Epub 2009 Aug 25.

PMID:
19712767
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Malaria blood stage parasites activate human plasmacytoid dendritic cells and murine dendritic cells through a Toll-like receptor 9-dependent pathway.

Pichyangkul S, Yongvanitchit K, Kum-arb U, Hemmi H, Akira S, Krieg AM, Heppner DG, Stewart VA, Hasegawa H, Looareesuwan S, Shanks GD, Miller RS.

J Immunol. 2004 Apr 15;172(8):4926-33.

PMID:
15067072
[PubMed - indexed for MEDLINE]
Free Article
20.

Adjuvant activity of polymer microparticles and Montanide ISA 720 on immune responses to Plasmodium falciparum MSP2 long synthetic peptides in mice.

Mata E, Carcaboso AM, Hernández RM, Igartua M, Corradin G, Pedraz JL.

Vaccine. 2007 Jan 15;25(5):877-85. Epub 2006 Sep 20.

PMID:
17070628
[PubMed - indexed for MEDLINE]

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