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Results: 1 to 20 of 189

1.

Identification of novel downstream targets of platelet glycoprotein VI activation by differential proteome analysis: implications for thrombus formation.

Schulz C, Leuschen NV, Fröhlich T, Lorenz M, Pfeiler S, Gleissner CA, Kremmer E, Kessler M, Khandoga AG, Engelmann B, Ley K, Massberg S, Arnold GJ.

Blood. 2010 May 20;115(20):4102-10. doi: 10.1182/blood-2009-07-230268. Epub 2010 Jan 27.

PMID:
20107233
[PubMed - indexed for MEDLINE]
Free Article
2.

CLP36 is a negative regulator of glycoprotein VI signaling in platelets.

Gupta S, Braun A, Morowski M, Premsler T, Bender M, Nagy Z, Sickmann A, Hermanns HM, Bösl M, Nieswandt B.

Circ Res. 2012 Nov 9;111(11):1410-20. doi: 10.1161/CIRCRESAHA.112.264754. Epub 2012 Sep 5.

PMID:
22955732
[PubMed - indexed for MEDLINE]
Free Article
3.

A functional proteomic method for the enrichment of peripheral membrane proteins reveals the collagen binding protein Hsp47 is exposed on the surface of activated human platelets.

Kaiser WJ, Holbrook LM, Tucker KL, Stanley RG, Gibbins JM.

J Proteome Res. 2009 Jun;8(6):2903-14. doi: 10.1021/pr900027j.

PMID:
19341245
[PubMed - indexed for MEDLINE]
4.

Non-redundant roles of phosphoinositide 3-kinase isoforms alpha and beta in glycoprotein VI-induced platelet signaling and thrombus formation.

Gilio K, Munnix IC, Mangin P, Cosemans JM, Feijge MA, van der Meijden PE, Olieslagers S, Chrzanowska-Wodnicka MB, Lillian R, Schoenwaelder S, Koyasu S, Sage SO, Jackson SP, Heemskerk JW.

J Biol Chem. 2009 Dec 4;284(49):33750-62. doi: 10.1074/jbc.M109.048439. Epub 2009 Oct 8.

PMID:
19815551
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

A familial platelet function disorder associated with abnormal signalling through the glycoprotein VI pathway.

Dunkley S, Arthur JF, Evans S, Gardiner EE, Shen Y, Andrews RK.

Br J Haematol. 2007 Jun;137(6):569-77.

PMID:
17539777
[PubMed - indexed for MEDLINE]
6.

The platelet receptor GPVI mediates both adhesion and signaling responses to collagen in a receptor density-dependent fashion.

Chen H, Locke D, Liu Y, Liu C, Kahn ML.

J Biol Chem. 2002 Jan 25;277(4):3011-9. Epub 2001 Nov 26.

PMID:
11723134
[PubMed - indexed for MEDLINE]
Free Article
7.

The glycoprotein VI-phospholipase Cgamma2 signaling pathway controls thrombus formation induced by collagen and tissue factor in vitro and in vivo.

Munnix IC, Strehl A, Kuijpers MJ, Auger JM, van der Meijden PE, van Zandvoort MA, oude Egbrink MG, Nieswandt B, Heemskerk JW.

Arterioscler Thromb Vasc Biol. 2005 Dec;25(12):2673-8. Epub 2005 Oct 27.

PMID:
16254207
[PubMed - indexed for MEDLINE]
Free Article
8.

Principal role of glycoprotein VI in alpha2beta1 and alphaIIbbeta3 activation during collagen-induced thrombus formation.

Lecut C, Schoolmeester A, Kuijpers MJ, Broers JL, van Zandvoort MA, Vanhoorelbeke K, Deckmyn H, Jandrot-Perrus M, Heemskerk JW.

Arterioscler Thromb Vasc Biol. 2004 Sep;24(9):1727-33. Epub 2004 Jul 1.

PMID:
15231520
[PubMed - indexed for MEDLINE]
Free Article
9.

Ex vivo inhibition of thrombus formation by an anti-glycoprotein VI Fab fragment in non-human primates without modification of glycoprotein VI expression.

Ohlmann P, Hechler B, Ravanat C, Loyau S, Herrenschmidt N, Wanert F, Jandrot-Perrus M, Gachet C.

J Thromb Haemost. 2008 Jun;6(6):1003-11. doi: 10.1111/j.1538-7836.2008.02976.x. Epub 2008 Apr 14.

PMID:
18419749
[PubMed - indexed for MEDLINE]
10.

Human atheromatous plaques stimulate thrombus formation by activating platelet glycoprotein VI.

Penz S, Reininger AJ, Brandl R, Goyal P, Rabie T, Bernlochner I, Rother E, Goetz C, Engelmann B, Smethurst PA, Ouwehand WH, Farndale R, Nieswandt B, Siess W.

FASEB J. 2005 Jun;19(8):898-909.

PMID:
15923400
[PubMed - indexed for MEDLINE]
Free Article
11.

Ligand binding rapidly induces disulfide-dependent dimerization of glycoprotein VI on the platelet plasma membrane.

Arthur JF, Shen Y, Kahn ML, Berndt MC, Andrews RK, Gardiner EE.

J Biol Chem. 2007 Oct 19;282(42):30434-41. Epub 2007 Aug 9.

PMID:
17690106
[PubMed - indexed for MEDLINE]
Free Article
12.

Anti-glycoprotein VI monoclonal antibodies directly aggregate platelets independently of FcgammaRIIa and induce GPVI ectodomain shedding.

Al-Tamimi M, Mu FT, Arthur JF, Shen Y, Moroi M, Berndt MC, Andrews RK, Gardiner EE.

Platelets. 2009 Mar;20(2):75-82. doi: 10.1080/09537100802645029.

PMID:
19235048
[PubMed - indexed for MEDLINE]
13.

Human platelet glycoprotein VI function is antagonized by monoclonal antibody-derived Fab fragments.

Lecut C, Feeney LA, Kingsbury G, Hopkins J, Lanza F, Gachet C, Villeval JL, Jandrot-Perrus M.

J Thromb Haemost. 2003 Dec;1(12):2653-62.

PMID:
14675102
[PubMed - indexed for MEDLINE]
14.

A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivo.

Massberg S, Gawaz M, Grüner S, Schulte V, Konrad I, Zohlnhöfer D, Heinzmann U, Nieswandt B.

J Exp Med. 2003 Jan 6;197(1):41-9.

PMID:
12515812
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Genetic analysis of the role of protein kinase Ctheta in platelet function and thrombus formation.

Hall KJ, Harper MT, Gilio K, Cosemans JM, Heemskerk JW, Poole AW.

PLoS One. 2008 Sep 25;3(9):e3277. doi: 10.1371/journal.pone.0003277.

PMID:
18815612
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Cloning, characterization, and functional studies of human and mouse glycoprotein VI: a platelet-specific collagen receptor from the immunoglobulin superfamily.

Jandrot-Perrus M, Busfield S, Lagrue AH, Xiong X, Debili N, Chickering T, Le Couedic JP, Goodearl A, Dussault B, Fraser C, Vainchenker W, Villeval JL.

Blood. 2000 Sep 1;96(5):1798-807.

PMID:
10961879
[PubMed - indexed for MEDLINE]
Free Article
17.

Platelet receptor signaling in thrombus formation.

Stegner D, Nieswandt B.

J Mol Med (Berl). 2011 Feb;89(2):109-21. doi: 10.1007/s00109-010-0691-5. Epub 2010 Nov 7. Review.

PMID:
21058007
[PubMed - indexed for MEDLINE]
18.

Soluble glycoprotein VI dimer inhibits platelet adhesion and aggregation to the injured vessel wall in vivo.

Massberg S, Konrad I, Bültmann A, Schulz C, Münch G, Peluso M, Lorenz M, Schneider S, Besta F, Müller I, Hu B, Langer H, Kremmer E, Rudelius M, Heinzmann U, Ungerer M, Gawaz M.

FASEB J. 2004 Feb;18(2):397-9. Epub 2003 Dec 4.

PMID:
14656994
[PubMed - indexed for MEDLINE]
Free Article
19.

Platelet activation and signal transduction by convulxin, a C-type lectin from Crotalus durissus terrificus (tropical rattlesnake) venom via the p62/GPVI collagen receptor.

Polgár J, Clemetson JM, Kehrel BE, Wiedemann M, Magnenat EM, Wells TN, Clemetson KJ.

J Biol Chem. 1997 May 23;272(21):13576-83.

PMID:
9153205
[PubMed - indexed for MEDLINE]
Free Article
20.

Platelet adhesion enhances the glycoprotein VI-dependent procoagulant response: Involvement of p38 MAP kinase and calpain.

Siljander P, Farndale RW, Feijge MA, Comfurius P, Kos S, Bevers EM, Heemskerk JW.

Arterioscler Thromb Vasc Biol. 2001 Apr;21(4):618-27.

PMID:
11304481
[PubMed - indexed for MEDLINE]
Free Article

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