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Results: 1 to 20 of 101

1.

Myosin VI: an innovative motor that challenged the swinging lever arm hypothesis.

Spudich JA, Sivaramakrishnan S.

Nat Rev Mol Cell Biol. 2010 Feb;11(2):128-37. doi: 10.1038/nrm2833. Review.

PMID:
20094053
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Processive steps in the reverse direction require uncoupling of the lead head lever arm of myosin VI.

Ménétrey J, Isabet T, Ropars V, Mukherjea M, Pylypenko O, Liu X, Perez J, Vachette P, Sweeney HL, Houdusse AM.

Mol Cell. 2012 Oct 12;48(1):75-86. doi: 10.1016/j.molcel.2012.07.034. Epub 2012 Aug 30.

PMID:
22940248
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Myosin VI undergoes a 180 degrees power stroke implying an uncoupling of the front lever arm.

Reifenberger JG, Toprak E, Kim H, Safer D, Sweeney HL, Selvin PR.

Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18255-60. doi: 10.1073/pnas.0900005106. Epub 2009 Oct 14.

PMID:
19828438
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Long single alpha-helical tail domains bridge the gap between structure and function of myosin VI.

Spink BJ, Sivaramakrishnan S, Lipfert J, Doniach S, Spudich JA.

Nat Struct Mol Biol. 2008 Jun;15(6):591-7. doi: 10.1038/nsmb.1429. Epub 2008 May 30.

PMID:
18511944
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The post-rigor structure of myosin VI and implications for the recovery stroke.

Ménétrey J, Llinas P, Cicolari J, Squires G, Liu X, Li A, Sweeney HL, Houdusse A.

EMBO J. 2008 Jan 9;27(1):244-52. Epub 2007 Nov 29.

PMID:
18046460
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Simultaneous observation of the lever arm and head explains myosin VI dual function.

Ikezaki K, Komori T, Sugawa M, Arai Y, Nishikawa S, Iwane AH, Yanagida T.

Small. 2012 Oct 8;8(19):3035-40. doi: 10.1002/smll.201200765. Epub 2012 Jul 9.

PMID:
22777889
[PubMed - indexed for MEDLINE]
7.

Reverse conformational changes of the light chain-binding domain of myosin V and VI processive motor heads during and after hydrolysis of ATP by small-angle X-ray solution scattering.

Sugimoto Y, Sato O, Watanabe S, Ikebe R, Ikebe M, Wakabayashi K.

J Mol Biol. 2009 Sep 18;392(2):420-35. doi: 10.1016/j.jmb.2009.07.013. Epub 2009 Jul 14.

PMID:
19607837
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Myosin VI is an actin-based motor that moves backwards.

Wells AL, Lin AW, Chen LQ, Safer D, Cain SM, Hasson T, Carragher BO, Milligan RA, Sweeney HL.

Nature. 1999 Sep 30;401(6752):505-8.

PMID:
10519557
[PubMed - indexed for MEDLINE]
9.

Myosin VI steps via a hand-over-hand mechanism with its lever arm undergoing fluctuations when attached to actin.

Yildiz A, Park H, Safer D, Yang Z, Chen LQ, Selvin PR, Sweeney HL.

J Biol Chem. 2004 Sep 3;279(36):37223-6. Epub 2004 Jul 14.

PMID:
15254036
[PubMed - indexed for MEDLINE]
Free Article
10.

Myosin VI dimerization triggers an unfolding of a three-helix bundle in order to extend its reach.

Mukherjea M, Llinas P, Kim H, Travaglia M, Safer D, Ménétrey J, Franzini-Armstrong C, Selvin PR, Houdusse A, Sweeney HL.

Mol Cell. 2009 Aug 14;35(3):305-15. doi: 10.1016/j.molcel.2009.07.010. Epub 2009 Aug 6.

PMID:
19664948
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The structural basis for the large powerstroke of myosin VI.

Ménétrey J, Llinas P, Mukherjea M, Sweeney HL, Houdusse A.

Cell. 2007 Oct 19;131(2):300-8.

PMID:
17956731
[PubMed - indexed for MEDLINE]
Free Article
12.

The power stroke of myosin VI and the basis of reverse directionality.

Bryant Z, Altman D, Spudich JA.

Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):772-7. Epub 2006 Dec 20.

PMID:
17182734
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Myosin VI walks hand-over-hand along actin.

Okten Z, Churchman LS, Rock RS, Spudich JA.

Nat Struct Mol Biol. 2004 Sep;11(9):884-7. Epub 2004 Aug 1.

PMID:
15286724
[PubMed - indexed for MEDLINE]
14.

Chemical decoupling of ATPase activation and force production from the contractile cycle in myosin by steric hindrance of lever-arm movement.

Muhlrad A, Peyser YM, Nili M, Ajtai K, Reisler E, Burghardt TP.

Biophys J. 2003 Feb;84(2 Pt 1):1047-56.

PMID:
12547786
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

A conformational transition in the myosin VI converter contributes to the variable step size.

Ovchinnikov V, Cecchini M, Vanden-Eijnden E, Karplus M.

Biophys J. 2011 Nov 16;101(10):2436-44. doi: 10.1016/j.bpj.2011.09.044. Epub 2011 Nov 15.

PMID:
22098742
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

The unique insert at the end of the myosin VI motor is the sole determinant of directionality.

Park H, Li A, Chen LQ, Houdusse A, Selvin PR, Sweeney HL.

Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):778-83. Epub 2007 Jan 9.

PMID:
17213313
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Nucleotide-dependent shape changes in the reverse direction motor, myosin VI.

Song CF, Sader K, White H, Kendrick-Jones J, Trinick J.

Biophys J. 2010 Nov 17;99(10):3336-44. doi: 10.1016/j.bpj.2010.09.014.

PMID:
21081082
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Extension of a three-helix bundle domain of myosin VI and key role of calmodulins.

Liu Y, Hsin J, Kim H, Selvin PR, Schulten K.

Biophys J. 2011 Jun 22;100(12):2964-73. doi: 10.1016/j.bpj.2011.05.010.

PMID:
21689530
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The structure of the myosin VI motor reveals the mechanism of directionality reversal.

Ménétrey J, Bahloul A, Wells AL, Yengo CM, Morris CA, Sweeney HL, Houdusse A.

Nature. 2005 Jun 9;435(7043):779-85.

PMID:
15944696
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Myosin VI walks "wiggly" on actin with large and variable tilting.

Sun Y, Schroeder HW 3rd, Beausang JF, Homma K, Ikebe M, Goldman YE.

Mol Cell. 2007 Dec 28;28(6):954-64.

PMID:
18158894
[PubMed - indexed for MEDLINE]
Free PMC Article

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