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Results: 1 to 20 of 168

Similar articles for PubMed (Select 20089532)

1.

DJ-1 deficient mice demonstrate similar vulnerability to pathogenic Ala53Thr human alpha-syn toxicity.

Ramsey CP, Tsika E, Ischiropoulos H, Giasson BI.

Hum Mol Genet. 2010 Apr 15;19(8):1425-37. doi: 10.1093/hmg/ddq017. Epub 2010 Jan 20.

2.

E46K human alpha-synuclein transgenic mice develop Lewy-like and tau pathology associated with age-dependent, detrimental motor impairment.

Emmer KL, Waxman EA, Covy JP, Giasson BI.

J Biol Chem. 2011 Oct 7;286(40):35104-18. doi: 10.1074/jbc.M111.247965. Epub 2011 Aug 16.

3.

DJ-1 modulates alpha-synuclein aggregation state in a cellular model of oxidative stress: relevance for Parkinson's disease and involvement of HSP70.

Batelli S, Albani D, Rametta R, Polito L, Prato F, Pesaresi M, Negro A, Forloni G.

PLoS One. 2008 Apr 2;3(4):e1884. doi: 10.1371/journal.pone.0001884.

4.

Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice.

Lee MK, Stirling W, Xu Y, Xu X, Qui D, Mandir AS, Dawson TM, Copeland NG, Jenkins NA, Price DL.

Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8968-73.

5.

Neurotoxic conversion of beta-synuclein: a novel approach to generate a transgenic mouse model of synucleinopathies?

Fujita M, Sekigawa A, Sekiyama K, Sugama S, Hashimoto M.

J Neurol. 2009 Aug;256 Suppl 3:286-92. doi: 10.1007/s00415-009-5246-8. Review.

PMID:
19711118
6.

Surprising behavioral and neurochemical enhancements in mice with combined mutations linked to Parkinson's disease.

Hennis MR, Marvin MA, Taylor CM 2nd, Goldberg MS.

Neurobiol Dis. 2014 Feb;62:113-23. doi: 10.1016/j.nbd.2013.09.009. Epub 2013 Sep 26.

7.

Neuroinflammation and α-synuclein dysfunction potentiate each other, driving chronic progression of neurodegeneration in a mouse model of Parkinson's disease.

Gao HM, Zhang F, Zhou H, Kam W, Wilson B, Hong JS.

Environ Health Perspect. 2011 Jun;119(6):807-14. doi: 10.1289/ehp.1003013. Epub 2011 Jan 18.

8.

Studies of protein aggregation in A53T α-synuclein transgenic, Tg2576 transgenic, and P246L presenilin-1 knock-in cross bred mice.

Emmer KL, Covy JP, Giasson BI.

Neurosci Lett. 2012 Jan 24;507(2):137-42. doi: 10.1016/j.neulet.2011.12.005. Epub 2011 Dec 13.

9.

Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death.

Martin LJ, Pan Y, Price AC, Sterling W, Copeland NG, Jenkins NA, Price DL, Lee MK.

J Neurosci. 2006 Jan 4;26(1):41-50.

10.

α-Synuclein transgenic mice reveal compensatory increases in Parkinson's disease-associated proteins DJ-1 and parkin and have enhanced α-synuclein and PINK1 levels after rotenone treatment.

George S, Mok SS, Nurjono M, Ayton S, Finkelstein DI, Masters CL, Li QX, Culvenor JG.

J Mol Neurosci. 2010 Oct;42(2):243-54. doi: 10.1007/s12031-010-9378-1. Epub 2010 May 13.

PMID:
20464527
11.

alpha -Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease.

Lo Bianco C, Ridet JL, Schneider BL, Deglon N, Aebischer P.

Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10813-8. Epub 2002 Jul 16.

12.

Pesticide exposure exacerbates alpha-synucleinopathy in an A53T transgenic mouse model.

Norris EH, Uryu K, Leight S, Giasson BI, Trojanowski JQ, Lee VM.

Am J Pathol. 2007 Feb;170(2):658-66.

13.

Differential effects of UCHL1 modulation on alpha-synuclein in PD-like models of alpha-synucleinopathy.

Cartier AE, Ubhi K, Spencer B, Vazquez-Roque RA, Kosberg KA, Fourgeaud L, Kanayson P, Patrick C, Rockenstein E, Patrick GN, Masliah E.

PLoS One. 2012;7(4):e34713. doi: 10.1371/journal.pone.0034713. Epub 2012 Apr 13.

14.

The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis.

Xu J, Zhong N, Wang H, Elias JE, Kim CY, Woldman I, Pifl C, Gygi SP, Geula C, Yankner BA.

Hum Mol Genet. 2005 May 1;14(9):1231-41. Epub 2005 Mar 24.

15.

Mimicking phosphorylation at serine 87 inhibits the aggregation of human α-synuclein and protects against its toxicity in a rat model of Parkinson's disease.

Oueslati A, Paleologou KE, Schneider BL, Aebischer P, Lashuel HA.

J Neurosci. 2012 Feb 1;32(5):1536-44. doi: 10.1523/JNEUROSCI.3784-11.2012.

16.

Pathological properties of the Parkinson's disease-associated protein DJ-1 in alpha-synucleinopathies and tauopathies: relevance for multiple system atrophy and Pick's disease.

Neumann M, Müller V, Görner K, Kretzschmar HA, Haass C, Kahle PJ.

Acta Neuropathol. 2004 Jun;107(6):489-96. Epub 2004 Feb 26.

PMID:
14991385
17.

DJ-1 associates with synaptic membranes.

Usami Y, Hatano T, Imai S, Kubo S, Sato S, Saiki S, Fujioka Y, Ohba Y, Sato F, Funayama M, Eguchi H, Shiba K, Ariga H, Shen J, Hattori N.

Neurobiol Dis. 2011 Sep;43(3):651-62. doi: 10.1016/j.nbd.2011.05.014. Epub 2011 May 30.

PMID:
21645620
18.

The role of alpha-synuclein oligomerization and aggregation in cellular and animal models of Parkinson's disease.

Wan OW, Chung KK.

PLoS One. 2012;7(6):e38545. doi: 10.1371/journal.pone.0038545. Epub 2012 Jun 12.

19.

DJ-1: a newcomer in Parkinson's disease pathology.

da Costa CA.

Curr Mol Med. 2007 Nov;7(7):650-7. Review.

PMID:
18045143
20.

α-Synuclein expression and Nrf2 deficiency cooperate to aggravate protein aggregation, neuronal death and inflammation in early-stage Parkinson's disease.

Lastres-Becker I, Ulusoy A, Innamorato NG, Sahin G, Rábano A, Kirik D, Cuadrado A.

Hum Mol Genet. 2012 Jul 15;21(14):3173-92. doi: 10.1093/hmg/dds143. Epub 2012 Apr 18.

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