Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Results: 1 to 20 of 136

1.

Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells.

Li F, Fernandez PP, Rajendran P, Hui KM, Sethi G.

Cancer Lett. 2010 Jun 28;292(2):197-207. doi: 10.1016/j.canlet.2009.12.003. Epub 2010 Jan 6.

PMID:
20053498
[PubMed - indexed for MEDLINE]
2.

γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent.

Rajendran P, Li F, Manu KA, Shanmugam MK, Loo SY, Kumar AP, Sethi G.

Br J Pharmacol. 2011 May;163(2):283-98. doi: 10.1111/j.1476-5381.2010.01187.x.

PMID:
21198544
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Honokiol inhibits signal transducer and activator of transcription-3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP-1.

Rajendran P, Li F, Shanmugam MK, Vali S, Abbasi T, Kapoor S, Ahn KS, Kumar AP, Sethi G.

J Cell Physiol. 2012 May;227(5):2184-95. doi: 10.1002/jcp.22954.

PMID:
21792937
[PubMed - indexed for MEDLINE]
4.

Identification of beta-escin as a novel inhibitor of signal transducer and activator of transcription 3/Janus-activated kinase 2 signaling pathway that suppresses proliferation and induces apoptosis in human hepatocellular carcinoma cells.

Tan SM, Li F, Rajendran P, Kumar AP, Hui KM, Sethi G.

J Pharmacol Exp Ther. 2010 Jul;334(1):285-93. doi: 10.1124/jpet.110.165498. Epub 2010 Apr 8.

PMID:
20378717
[PubMed - indexed for MEDLINE]
Free Article
5.

Deactivation of Akt and STAT3 signaling promotes apoptosis, inhibits proliferation, and enhances the sensitivity of hepatocellular carcinoma cells to an anticancer agent, Atiprimod.

Choudhari SR, Khan MA, Harris G, Picker D, Jacob GS, Block T, Shailubhai K.

Mol Cancer Ther. 2007 Jan;6(1):112-21.

PMID:
17237271
[PubMed - indexed for MEDLINE]
Free Article
6.

Capsaicin is a novel blocker of constitutive and interleukin-6-inducible STAT3 activation.

Bhutani M, Pathak AK, Nair AS, Kunnumakkara AB, Guha S, Sethi G, Aggarwal BB.

Clin Cancer Res. 2007 May 15;13(10):3024-32.

PMID:
17505005
[PubMed - indexed for MEDLINE]
Free Article
7.

Butein suppresses constitutive and inducible signal transducer and activator of transcription (STAT) 3 activation and STAT3-regulated gene products through the induction of a protein tyrosine phosphatase SHP-1.

Pandey MK, Sung B, Ahn KS, Aggarwal BB.

Mol Pharmacol. 2009 Mar;75(3):525-33. doi: 10.1124/mol.108.052548. Epub 2008 Dec 22.

PMID:
19103760
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Arctigenin enhances chemosensitivity of cancer cells to cisplatin through inhibition of the STAT3 signaling pathway.

Yao X, Zhu F, Zhao Z, Liu C, Luo L, Yin Z.

J Cell Biochem. 2011 Oct;112(10):2837-49. doi: 10.1002/jcb.23198.

PMID:
21608020
[PubMed - indexed for MEDLINE]
9.

Evodiamine inhibits STAT3 signaling by inducing phosphatase shatterproof 1 in hepatocellular carcinoma cells.

Yang J, Cai X, Lu W, Hu C, Xu X, Yu Q, Cao P.

Cancer Lett. 2013 Jan 28;328(2):243-51. doi: 10.1016/j.canlet.2012.09.019. Epub 2012 Sep 29.

PMID:
23032719
[PubMed - indexed for MEDLINE]
10.

Ursolic acid inhibits STAT3 activation pathway leading to suppression of proliferation and chemosensitization of human multiple myeloma cells.

Pathak AK, Bhutani M, Nair AS, Ahn KS, Chakraborty A, Kadara H, Guha S, Sethi G, Aggarwal BB.

Mol Cancer Res. 2007 Sep;5(9):943-55.

PMID:
17855663
[PubMed - indexed for MEDLINE]
Free Article
11.
12.

The oncogenic effects of constitutive Stat3 signaling in salivary gland cancer cells are mediated by survivin and modulated by the NSAID sulindac.

Nikitakis NG, Scheper MA, Papanikolaou VS, Sauk JJ.

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Jun;107(6):826-36. doi: 10.1016/j.tripleo.2008.12.054. Epub 2009 Mar 9.

PMID:
19272804
[PubMed - indexed for MEDLINE]
13.

Jak inhibitor induces S phase cell-cycle arrest and augments TRAIL-induced apoptosis in human hepatocellular carcinoma cells.

Fuke H, Shiraki K, Sugimoto K, Tanaka J, Beppu T, Yoneda K, Yamamoto N, Ito K, Masuya M, Takei Y.

Biochem Biophys Res Commun. 2007 Nov 23;363(3):738-44. Epub 2007 Sep 21.

PMID:
17904524
[PubMed - indexed for MEDLINE]
14.
15.

Survivin overexpression in HCC and liver cirrhosis differentially correlates with p-STAT3 and E-cadherin.

Peroukides S, Bravou V, Alexopoulos A, Varakis J, Kalofonos H, Papadaki H.

Histol Histopathol. 2010 Mar;25(3):299-307.

PMID:
20054802
[PubMed - indexed for MEDLINE]
16.

EGFR is phosphorylated at Ty845 in hepatocellular carcinoma.

Kannangai R, Sahin F, Torbenson MS.

Mod Pathol. 2006 Nov;19(11):1456-61. Epub 2006 Aug 25.

PMID:
16936701
[PubMed - indexed for MEDLINE]
Free Article
17.

Guggulsterone, a farnesoid X receptor antagonist, inhibits constitutive and inducible STAT3 activation through induction of a protein tyrosine phosphatase SHP-1.

Ahn KS, Sethi G, Sung B, Goel A, Ralhan R, Aggarwal BB.

Cancer Res. 2008 Jun 1;68(11):4406-15. doi: 10.1158/0008-5472.CAN-07-6696.

PMID:
18519703
[PubMed - indexed for MEDLINE]
Free Article
18.

Celastrol suppresses growth and induces apoptosis of human hepatocellular carcinoma through the modulation of STAT3/JAK2 signaling cascade in vitro and in vivo.

Rajendran P, Li F, Shanmugam MK, Kannaiyan R, Goh JN, Wong KF, Wang W, Khin E, Tergaonkar V, Kumar AP, Luk JM, Sethi G.

Cancer Prev Res (Phila). 2012 Apr;5(4):631-43. doi: 10.1158/1940-6207.CAPR-11-0420. Epub 2012 Feb 27.

PMID:
22369852
[PubMed - indexed for MEDLINE]
19.

Targeted constitutive activation of signal transducer and activator of transcription 3 in human hepatocellular carcinoma cells by cucurbitacin B.

Zhang M, Zhang H, Sun C, Shan X, Yang X, Li-Ling J, Deng Y.

Cancer Chemother Pharmacol. 2009 Mar;63(4):635-42. doi: 10.1007/s00280-008-0780-0. Epub 2008 Jun 3.

PMID:
18521604
[PubMed - indexed for MEDLINE]
20.

Nitidine chloride inhibits hepatocellular carcinoma cell growth in vivo through the suppression of the JAK1/STAT3 signaling pathway.

Liao J, Xu T, Zheng JX, Lin JM, Cai QY, Yu DB, Peng J.

Int J Mol Med. 2013 Jul;32(1):79-84. doi: 10.3892/ijmm.2013.1358. Epub 2013 Apr 22.

PMID:
23613111
[PubMed - indexed for MEDLINE]

Display Settings:

Format
Items per page
Sort by

Send to:

Choose Destination

Supplemental Content

Write to the Help Desk