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Items: 1 to 20 of 87

2.

Tuberin regulates the DNA repair enzyme OGG1.

Habib SL, Riley DJ, Mahimainathan L, Bhandari B, Choudhury GG, Abboud HE.

Am J Physiol Renal Physiol. 2008 Jan;294(1):F281-90. Epub 2007 Nov 7.

3.

Insight into mechanism of oxidative DNA damage in angiomyolipomas from TSC patients.

Habib SL.

Mol Cancer. 2009 Mar 5;8:13. doi: 10.1186/1476-4598-8-13.

4.

Tuberin haploinsufficiency is associated with the loss of OGG1 in rat kidney tumors.

Habib SL, Simone S, Barnes JJ, Abboud HE.

Mol Cancer. 2008 Jan 24;7:10. doi: 10.1186/1476-4598-7-10.

5.

Novel mechanism of regulation of the DNA repair enzyme OGG1 in tuberin-deficient cells.

Habib SL, Bhandari BK, Sadek N, Abboud-Werner SL, Abboud HE.

Carcinogenesis. 2010 Nov;31(11):2022-30. doi: 10.1093/carcin/bgq189. Epub 2010 Sep 13.

6.

Tuberous sclerosis complex and DNA repair.

Habib SL.

Adv Exp Med Biol. 2010;685:84-94. Review.

PMID:
20687497
7.
8.

Mechanism of oxidative DNA damage in diabetes: tuberin inactivation and downregulation of DNA repair enzyme 8-oxo-7,8-dihydro-2'-deoxyguanosine-DNA glycosylase.

Simone S, Gorin Y, Velagapudi C, Abboud HE, Habib SL.

Diabetes. 2008 Oct;57(10):2626-36. doi: 10.2337/db07-1579. Epub 2008 Jul 3.

9.
10.

Regulation of PI 3-K, PTEN, p53, and mTOR in Malignant and Benign Tumors Deficient in Tuberin.

Habib SL, Yadav A, Mahimainathan L, Valente AJ.

Genes Cancer. 2011 Nov;2(11):1051-60. doi: 10.1177/1947601912445376.

11.

Suppression of tumorigenicity by the wild-type tuberous sclerosis 2 (Tsc2) gene and its C-terminal region.

Jin F, Wienecke R, Xiao GH, Maize JC Jr, DeClue JE, Yeung RS.

Proc Natl Acad Sci U S A. 1996 Aug 20;93(17):9154-9.

12.

Localization of tuberous sclerosis 2 mRNA and its protein product tuberin in normal human brain and in cerebral lesions of patients with tuberous sclerosis.

Kerfoot C, Wienecke R, Menchine M, Emelin J, Maize JC Jr, Welsh CT, Norman MG, DeClue JE, Vinters HV.

Brain Pathol. 1996 Oct;6(4):367-75.

PMID:
8944308
13.

Novel mechanism of reducing tumourigenesis: upregulation of the DNA repair enzyme OGG1 by rapamycin-mediated AMPK activation and mTOR inhibition.

Habib SL, Kasinath BS, Arya RR, Vexler S, Velagapudi C.

Eur J Cancer. 2010 Oct;46(15):2806-20. doi: 10.1016/j.ejca.2010.06.117. Epub 2010 Jul 23.

PMID:
20656472
14.

The expression of hamartin, the product of the TSC1 gene, in normal human tissues and in TSC1- and TSC2-linked angiomyolipomas.

Plank TL, Logginidou H, Klein-Szanto A, Henske EP.

Mod Pathol. 1999 May;12(5):539-45.

PMID:
10349994
15.

Loss of tuberin in both subependymal giant cell astrocytomas and angiomyolipomas supports a two-hit model for the pathogenesis of tuberous sclerosis tumors.

Henske EP, Wessner LL, Golden J, Scheithauer BW, Vortmeyer AO, Zhuang Z, Klein-Szanto AJ, Kwiatkowski DJ, Yeung RS.

Am J Pathol. 1997 Dec;151(6):1639-47.

16.

Renal carcinogenesis, hepatic hemangiomatosis, and embryonic lethality caused by a germ-line Tsc2 mutation in mice.

Kobayashi T, Minowa O, Kuno J, Mitani H, Hino O, Noda T.

Cancer Res. 1999 Mar 15;59(6):1206-11.

18.

Tuberous sclerosis in a 19-week fetus: immunohistochemical and molecular study of hamartin and tuberin.

Wei J, Li P, Chiriboga L, Mizuguchi M, Yee H, Miller DC, Greco MA.

Pediatr Dev Pathol. 2002 Sep-Oct;5(5):448-64. Epub 2002 Sep 4.

PMID:
12202993
19.

Tuberin, the tuberous sclerosis complex 2 tumor suppressor gene product, regulates Rho activation, cell adhesion and migration.

Astrinidis A, Cash TP, Hunter DS, Walker CL, Chernoff J, Henske EP.

Oncogene. 2002 Dec 5;21(55):8470-6.

20.
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