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Items: 1 to 20 of 102

1.

Mutation of conserved cysteines in the Ly6 domain of GPIHBP1 in familial chylomicronemia.

Olivecrona G, Ehrenborg E, Semb H, Makoveichuk E, Lindberg A, Hayden MR, Gin P, Davies BS, Weinstein MM, Fong LG, Beigneux AP, Young SG, Olivecrona T, Hernell O.

J Lipid Res. 2010 Jun;51(6):1535-45. doi: 10.1194/jlr.M002717. Epub 2009 Dec 21.

2.

Chylomicronemia with low postheparin lipoprotein lipase levels in the setting of GPIHBP1 defects.

Franssen R, Young SG, Peelman F, Hertecant J, Sierts JA, Schimmel AW, Bensadoun A, Kastelein JJ, Fong LG, Dallinga-Thie GM, Beigneux AP.

Circ Cardiovasc Genet. 2010 Apr;3(2):169-78. doi: 10.1161/CIRCGENETICS.109.908905. Epub 2010 Feb 2.

3.

Assessing the role of the glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) three-finger domain in binding lipoprotein lipase.

Beigneux AP, Davies BS, Tat S, Chen J, Gin P, Voss CV, Weinstein MM, Bensadoun A, Pullinger CR, Fong LG, Young SG.

J Biol Chem. 2011 Jun 3;286(22):19735-43. doi: 10.1074/jbc.M111.242024. Epub 2011 Apr 7.

4.

Chylomicronemia with a mutant GPIHBP1 (Q115P) that cannot bind lipoprotein lipase.

Beigneux AP, Franssen R, Bensadoun A, Gin P, Melford K, Peter J, Walzem RL, Weinstein MM, Davies BS, Kuivenhoven JA, Kastelein JJ, Fong LG, Dallinga-Thie GM, Young SG.

Arterioscler Thromb Vasc Biol. 2009 Jun;29(6):956-62. doi: 10.1161/ATVBAHA.109.186577. Epub 2009 Mar 19.

5.

GPIHBP1 missense mutations often cause multimerization of GPIHBP1 and thereby prevent lipoprotein lipase binding.

Beigneux AP, Fong LG, Bensadoun A, Davies BS, Oberer M, Gårdsvoll H, Ploug M, Young SG.

Circ Res. 2015 Feb 13;116(4):624-32. doi: 10.1161/CIRCRESAHA.116.305085. Epub 2014 Nov 11.

6.

Binding preferences for GPIHBP1, a glycosylphosphatidylinositol-anchored protein of capillary endothelial cells.

Gin P, Beigneux AP, Voss C, Davies BS, Beckstead JA, Ryan RO, Bensadoun A, Fong LG, Young SG.

Arterioscler Thromb Vasc Biol. 2011 Jan;31(1):176-82. doi: 10.1161/ATVBAHA.110.214718. Epub 2010 Oct 21.

7.

Multimerization of glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (GPIHBP1) and familial chylomicronemia from a serine-to-cysteine substitution in GPIHBP1 Ly6 domain.

Plengpanich W, Young SG, Khovidhunkit W, Bensadoun A, Karnman H, Ploug M, Gårdsvoll H, Leung CS, Adeyo O, Larsson M, Muanpetch S, Charoen S, Fong LG, Niramitmahapanya S, Beigneux AP.

J Biol Chem. 2014 Jul 11;289(28):19491-9. doi: 10.1074/jbc.M114.558528. Epub 2014 May 20.

8.

Mutations in lipoprotein lipase that block binding to the endothelial cell transporter GPIHBP1.

Voss CV, Davies BS, Tat S, Gin P, Fong LG, Pelletier C, Mottler CD, Bensadoun A, Beigneux AP, Young SG.

Proc Natl Acad Sci U S A. 2011 May 10;108(19):7980-4. doi: 10.1073/pnas.1100992108. Epub 2011 Apr 25.

9.

Highly conserved cysteines within the Ly6 domain of GPIHBP1 are crucial for the binding of lipoprotein lipase.

Beigneux AP, Gin P, Davies BS, Weinstein MM, Bensadoun A, Fong LG, Young SG.

J Biol Chem. 2009 Oct 30;284(44):30240-7. doi: 10.1074/jbc.M109.046391. Epub 2009 Sep 2.

10.

GPIHBP1 C89F neomutation and hydrophobic C-terminal domain G175R mutation in two pedigrees with severe hyperchylomicronemia.

Charrière S, Peretti N, Bernard S, Di Filippo M, Sassolas A, Merlin M, Delay M, Debard C, Lefai E, Lachaux A, Moulin P, Marçais C.

J Clin Endocrinol Metab. 2011 Oct;96(10):E1675-9. doi: 10.1210/jc.2011-1444. Epub 2011 Aug 3.

PMID:
21816778
11.

The acidic domain of GPIHBP1 is important for the binding of lipoprotein lipase and chylomicrons.

Gin P, Yin L, Davies BS, Weinstein MM, Ryan RO, Bensadoun A, Fong LG, Young SG, Beigneux AP.

J Biol Chem. 2008 Oct 24;283(43):29554-62. doi: 10.1074/jbc.M802579200. Epub 2008 Aug 18.

12.

Normal binding of lipoprotein lipase, chylomicrons, and apo-AV to GPIHBP1 containing a G56R amino acid substitution.

Gin P, Beigneux AP, Davies B, Young MF, Ryan RO, Bensadoun A, Fong LG, Young SG.

Biochim Biophys Acta. 2007 Dec;1771(12):1464-8. Epub 2007 Oct 22.

13.

GPIHBP1, an endothelial cell transporter for lipoprotein lipase.

Young SG, Davies BS, Voss CV, Gin P, Weinstein MM, Tontonoz P, Reue K, Bensadoun A, Fong LG, Beigneux AP.

J Lipid Res. 2011 Nov;52(11):1869-84. doi: 10.1194/jlr.R018689. Epub 2011 Aug 15. Review.

14.

Chylomicronemia mutations yield new insights into interactions between lipoprotein lipase and GPIHBP1.

Gin P, Goulbourne CN, Adeyo O, Beigneux AP, Davies BS, Tat S, Voss CV, Bensadoun A, Fong LG, Young SG.

Hum Mol Genet. 2012 Jul 1;21(13):2961-72. doi: 10.1093/hmg/dds127. Epub 2012 Apr 6.

15.

Evidence for Two Distinct Binding Sites for Lipoprotein Lipase on Glycosylphosphatidylinositol-anchored High Density Lipoprotein-binding Protein 1 (GPIHBP1).

Reimund M, Larsson M, Kovrov O, Kasvandik S, Olivecrona G, Lookene A.

J Biol Chem. 2015 May 29;290(22):13919-34. doi: 10.1074/jbc.M114.634626. Epub 2015 Apr 14.

PMID:
25873395
16.

Abnormal patterns of lipoprotein lipase release into the plasma in GPIHBP1-deficient mice.

Weinstein MM, Yin L, Beigneux AP, Davies BS, Gin P, Estrada K, Melford K, Bishop JR, Esko JD, Dallinga-Thie GM, Fong LG, Bensadoun A, Young SG.

J Biol Chem. 2008 Dec 12;283(50):34511-8. doi: 10.1074/jbc.M806067200. Epub 2008 Oct 8. Erratum in: J Biol Chem. 2009 Feb 6;284(6):4040.

17.

GPIHBP1 and the processing of triglyceride-rich lipoproteins.

Beigneux AP.

Clin Lipidol. 2010 Aug 1;5(4):575-582.

18.

Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 plays a critical role in the lipolytic processing of chylomicrons.

Beigneux AP, Davies BS, Gin P, Weinstein MM, Farber E, Qiao X, Peale F, Bunting S, Walzem RL, Wong JS, Blaner WS, Ding ZM, Melford K, Wongsiriroj N, Shu X, de Sauvage F, Ryan RO, Fong LG, Bensadoun A, Young SG.

Cell Metab. 2007 Apr;5(4):279-91.

19.

GPIHBP1 and lipolysis: an update.

Beigneux AP, Weinstein MM, Davies BS, Gin P, Bensadoun A, Fong LG, Young SG.

Curr Opin Lipidol. 2009 Jun;20(3):211-6. doi: 10.1097/MOL.0b013e32832ac026. Review.

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