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Results: 1 to 20 of 95

1.

The potent anti-HIV activity of CXCL12gamma correlates with efficient CXCR4 binding and internalization.

Altenburg JD, Jin Q, Alkhatib B, Alkhatib G.

J Virol. 2010 Mar;84(5):2563-72. doi: 10.1128/JVI.00342-09. Epub 2009 Dec 16.

PMID:
20015992
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

A naturally occurring splice variant of CXCL12/stromal cell-derived factor 1 is a potent human immunodeficiency virus type 1 inhibitor with weak chemotaxis and cell survival activities.

Altenburg JD, Broxmeyer HE, Jin Q, Cooper S, Basu S, Alkhatib G.

J Virol. 2007 Aug;81(15):8140-8. Epub 2007 May 16.

PMID:
17507482
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The CXCL12gamma chemokine displays unprecedented structural and functional properties that make it a paradigm of chemoattractant proteins.

Rueda P, Balabanian K, Lagane B, Staropoli I, Chow K, Levoye A, Laguri C, Sadir R, Delaunay T, Izquierdo E, Pablos JL, Lendinez E, Caruz A, Franco D, Baleux F, Lortat-Jacob H, Arenzana-Seisdedos F.

PLoS One. 2008 Jul 2;3(7):e2543. doi: 10.1371/journal.pone.0002543.

PMID:
18648536
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The novel CXCL12gamma isoform encodes an unstructured cationic domain which regulates bioactivity and interaction with both glycosaminoglycans and CXCR4.

Laguri C, Sadir R, Rueda P, Baleux F, Gans P, Arenzana-Seisdedos F, Lortat-Jacob H.

PLoS One. 2007 Oct 31;2(10):e1110.

PMID:
17971873
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

CXCL12γ isoform is expressed on endothelial and dendritic cells in rheumatoid arthritis synovium and regulates T cell activation.

Santiago B, Izquierdo E, Rueda P, Del Rey MJ, Criado G, Usategui A, Arenzana-Seisdedos F, Pablos JL.

Arthritis Rheum. 2012 Feb;64(2):409-17. doi: 10.1002/art.33345.

PMID:
21953583
[PubMed - indexed for MEDLINE]
Free Article
6.

Neutralising properties of peptides derived from CXCR4 extracellular loops towards CXCL12 binding and HIV-1 infection.

Chevigné A, Fievez V, Szpakowska M, Fischer A, Counson M, Plesséria JM, Schmit JC, Deroo S.

Biochim Biophys Acta. 2014 May;1843(5):1031-41. doi: 10.1016/j.bbamcr.2014.01.017. Epub 2014 Jan 27.

PMID:
24480462
[PubMed - indexed for MEDLINE]
7.

Optimal inhibition of X4 HIV isolates by the CXC chemokine stromal cell-derived factor 1 alpha requires interaction with cell surface heparan sulfate proteoglycans.

Valenzuela-Fernández A, Palanche T, Amara A, Magerus A, Altmeyer R, Delaunay T, Virelizier JL, Baleux F, Galzi JL, Arenzana-Seisdedos F.

J Biol Chem. 2001 Jul 13;276(28):26550-8. Epub 2001 May 14.

PMID:
11352904
[PubMed - indexed for MEDLINE]
Free Article
8.

Identification of residues of CXCR4 critical for human immunodeficiency virus coreceptor and chemokine receptor activities.

Brelot A, Heveker N, Montes M, Alizon M.

J Biol Chem. 2000 Aug 4;275(31):23736-44.

PMID:
10825158
[PubMed - indexed for MEDLINE]
Free Article
9.

Separate elements are required for ligand-dependent and -independent internalization of metastatic potentiator CXCR4.

Futahashi Y, Komano J, Urano E, Aoki T, Hamatake M, Miyauchi K, Yoshida T, Koyanagi Y, Matsuda Z, Yamamoto N.

Cancer Sci. 2007 Mar;98(3):373-9.

PMID:
17270027
[PubMed - indexed for MEDLINE]
10.

Plectin regulates the signaling and trafficking of the HIV-1 co-receptor CXCR4 and plays a role in HIV-1 infection.

Ding Y, Zhang L, Goodwin JS, Wang Z, Liu B, Zhang J, Fan GH.

Exp Cell Res. 2008 Feb 1;314(3):590-602. Epub 2007 Nov 17.

PMID:
18155192
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Trafficking of the HIV coreceptor CXCR4. Role of arrestins and identification of residues in the c-terminal tail that mediate receptor internalization.

Orsini MJ, Parent JL, Mundell SJ, Marchese A, Benovic JL.

J Biol Chem. 1999 Oct 22;274(43):31076-86. Erratum in: J Biol Chem 2000 Aug 18;275(33):25876. Marchese, Adriano [added].

PMID:
10521508
[PubMed - indexed for MEDLINE]
Free Article
12.

The CXC chemokine receptor 4 ligands ubiquitin and stromal cell-derived factor-1α function through distinct receptor interactions.

Saini V, Staren DM, Ziarek JJ, Nashaat ZN, Campbell EM, Volkman BF, Marchese A, Majetschak M.

J Biol Chem. 2011 Sep 23;286(38):33466-77. doi: 10.1074/jbc.M111.233742. Epub 2011 Jul 13.

PMID:
21757744
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The role of N-glycosylation sites on the CXCR4 receptor for CXCL-12 binding and signaling and X4 HIV-1 viral infectivity.

Huskens D, Princen K, Schreiber M, Schols D.

Virology. 2007 Jul 5;363(2):280-7. Epub 2007 Feb 28.

PMID:
17331556
[PubMed - indexed for MEDLINE]
Free Article
14.

Citrullination of CXCL12 differentially reduces CXCR4 and CXCR7 binding with loss of inflammatory and anti-HIV-1 activity via CXCR4.

Struyf S, Noppen S, Loos T, Mortier A, Gouwy M, Verbeke H, Huskens D, Luangsay S, Parmentier M, Geboes K, Schols D, Van Damme J, Proost P.

J Immunol. 2009 Jan 1;182(1):666-74.

PMID:
19109200
[PubMed - indexed for MEDLINE]
Free Article
15.

Cloning and characterizing mutated human stromal cell-derived factor-1 (SDF-1): C-terminal alpha-helix of SDF-1alpha plays a critical role in CXCR4 activation and signaling, but not in CXCR4 binding affinity.

Tan Y, Du J, Cai S, Li X, Ma W, Guo Z, Chen H, Huang Z, Xiao J, Cai L, Cai S.

Exp Hematol. 2006 Nov;34(11):1553-62.

PMID:
17046575
[PubMed - indexed for MEDLINE]
16.

N-linked glycosylation in the CXCR4 N-terminus inhibits binding to HIV-1 envelope glycoproteins.

Wang J, Babcock GJ, Choe H, Farzan M, Sodroski J, Gabuzda D.

Virology. 2004 Jun 20;324(1):140-50.

PMID:
15183061
[PubMed - indexed for MEDLINE]
Free Article
17.

Mutation of Asp(171) and Asp(262) of the chemokine receptor CXCR4 impairs its coreceptor function for human immunodeficiency virus-1 entry and abrogates the antagonistic activity of AMD3100.

Hatse S, Princen K, Gerlach LO, Bridger G, Henson G, De Clercq E, Schwartz TW, Schols D.

Mol Pharmacol. 2001 Jul;60(1):164-73.

PMID:
11408611
[PubMed - indexed for MEDLINE]
Free Article
18.

CD4-Chemokine receptor hybrids in human immunodeficiency virus type 1 infection.

Klasse PJ, Rosenkilde MM, Signoret N, Pelchen-Matthews A, Schwartz TW, Marsh M.

J Virol. 1999 Sep;73(9):7453-66.

PMID:
10438835
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Identification of CXCR4 domains that support coreceptor and chemokine receptor functions.

Doranz BJ, Orsini MJ, Turner JD, Hoffman TL, Berson JF, Hoxie JA, Peiper SC, Brass LF, Doms RW.

J Virol. 1999 Apr;73(4):2752-61.

PMID:
10074122
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Structural basis of the interaction between chemokine stromal cell-derived factor-1/CXCL12 and its G-protein-coupled receptor CXCR4.

Kofuku Y, Yoshiura C, Ueda T, Terasawa H, Hirai T, Tominaga S, Hirose M, Maeda Y, Takahashi H, Terashima Y, Matsushima K, Shimada I.

J Biol Chem. 2009 Dec 11;284(50):35240-50. doi: 10.1074/jbc.M109.024851. Epub 2009 Oct 18.

PMID:
19837984
[PubMed - indexed for MEDLINE]
Free PMC Article

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