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Items: 1 to 20 of 594

1.

Targeted disruption of NF-{kappa}B1 (p50) augments cigarette smoke-induced lung inflammation and emphysema in mice: a critical role of p50 in chromatin remodeling.

Rajendrasozhan S, Chung S, Sundar IK, Yao H, Rahman I.

Am J Physiol Lung Cell Mol Physiol. 2010 Feb;298(2):L197-209. doi: 10.1152/ajplung.00265.2009. Epub 2009 Dec 4.

2.

Glutaredoxin 1 regulates cigarette smoke-mediated lung inflammation through differential modulation of I{kappa}B kinases in mice: impact on histone acetylation.

Chung S, Sundar IK, Yao H, Ho YS, Rahman I.

Am J Physiol Lung Cell Mol Physiol. 2010 Aug;299(2):L192-203. doi: 10.1152/ajplung.00426.2009. Epub 2010 May 14.

3.

IKK alpha causes chromatin modification on pro-inflammatory genes by cigarette smoke in mouse lung.

Yang SR, Valvo S, Yao H, Kode A, Rajendrasozhan S, Edirisinghe I, Caito S, Adenuga D, Henry R, Fromm G, Maggirwar S, Li JD, Bulger M, Rahman I.

Am J Respir Cell Mol Biol. 2008 Jun;38(6):689-98. doi: 10.1165/rcmb.2007-0379OC. Epub 2008 Jan 31.

4.

Mitogen- and stress-activated kinase 1 (MSK1) regulates cigarette smoke-induced histone modifications on NF-κB-dependent genes.

Sundar IK, Chung S, Hwang JW, Lapek JD Jr, Bulger M, Friedman AE, Yao H, Davie JR, Rahman I.

PLoS One. 2012;7(2):e31378. doi: 10.1371/journal.pone.0031378. Epub 2012 Feb 1.

5.

Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-kappaB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging.

Yang SR, Wright J, Bauter M, Seweryniak K, Kode A, Rahman I.

Am J Physiol Lung Cell Mol Physiol. 2007 Feb;292(2):L567-76. Epub 2006 Oct 13.

6.

RelB is differentially regulated by IkappaB Kinase-alpha in B cells and mouse lung by cigarette smoke.

Yang SR, Yao H, Rajendrasozhan S, Chung S, Edirisinghe I, Valvo S, Fromm G, McCabe MJ Jr, Sime PJ, Phipps RP, Li JD, Bulger M, Rahman I.

Am J Respir Cell Mol Biol. 2009 Feb;40(2):147-58. doi: 10.1165/rcmb.2008-0207OC. Epub 2008 Aug 7.

7.

Protein kinase C zeta mediates cigarette smoke/aldehyde- and lipopolysaccharide-induced lung inflammation and histone modifications.

Yao H, Hwang JW, Moscat J, Diaz-Meco MT, Leitges M, Kishore N, Li X, Rahman I.

J Biol Chem. 2010 Feb 19;285(8):5405-16. doi: 10.1074/jbc.M109.041418. Epub 2009 Dec 11.

8.

Cigarette smoke-induced pulmonary inflammation and emphysema are attenuated in CCR6-deficient mice.

Bracke KR, D'hulst AI, Maes T, Moerloose KB, Demedts IK, Lebecque S, Joos GF, Brusselle GG.

J Immunol. 2006 Oct 1;177(7):4350-9.

9.

Cigarette smoke-induced pulmonary inflammation, but not airway remodelling, is attenuated in chemokine receptor 5-deficient mice.

Bracke KR, D'hulst AI, Maes T, Demedts IK, Moerloose KB, Kuziel WA, Joos GF, Brusselle GG.

Clin Exp Allergy. 2007 Oct;37(10):1467-79.

PMID:
17883726
11.

Thioredoxin-1 ameliorates cigarette smoke-induced lung inflammation and emphysema in mice.

Sato A, Hoshino Y, Hara T, Muro S, Nakamura H, Mishima M, Yodoi J.

J Pharmacol Exp Ther. 2008 May;325(2):380-8. doi: 10.1124/jpet.107.134007. Epub 2008 Feb 6.

12.

Lack of essential role of NF-kappa B p50, RelA, and cRel subunits in virus-induced type 1 IFN expression.

Wang X, Hussain S, Wang EJ, Wang X, Li MO, García-Sastre A, Beg AA.

J Immunol. 2007 Jun 1;178(11):6770-6.

13.

Genetic ablation of NADPH oxidase enhances susceptibility to cigarette smoke-induced lung inflammation and emphysema in mice.

Yao H, Edirisinghe I, Yang SR, Rajendrasozhan S, Kode A, Caito S, Adenuga D, Rahman I.

Am J Pathol. 2008 May;172(5):1222-37. doi: 10.2353/ajpath.2008.070765. Epub 2008 Apr 10.

14.

Cigarette smoke-mediated inflammatory and oxidative responses are strain-dependent in mice.

Yao H, Edirisinghe I, Rajendrasozhan S, Yang SR, Caito S, Adenuga D, Rahman I.

Am J Physiol Lung Cell Mol Physiol. 2008 Jun;294(6):L1174-86. doi: 10.1152/ajplung.00439.2007. Epub 2008 Mar 28.

15.

A role for NF-kappa B subunits p50 and p65 in the inhibition of lipopolysaccharide-induced shock.

Gadjeva M, Tomczak MF, Zhang M, Wang YY, Dull K, Rogers AB, Erdman SE, Fox JG, Carroll M, Horwitz BH.

J Immunol. 2004 Nov 1;173(9):5786-93.

16.

Cigarette smoke alters chromatin remodeling and induces proinflammatory genes in rat lungs.

Marwick JA, Kirkham PA, Stevenson CS, Danahay H, Giddings J, Butler K, Donaldson K, Macnee W, Rahman I.

Am J Respir Cell Mol Biol. 2004 Dec;31(6):633-42. Epub 2004 Aug 27.

PMID:
15333327
17.

Targeted deletion of nuclear factor kappaB p50 enhances cardiac remodeling and dysfunction following myocardial infarction.

Timmers L, van Keulen JK, Hoefer IE, Meijs MF, van Middelaar B, den Ouden K, van Echteld CJ, Pasterkamp G, de Kleijn DP.

Circ Res. 2009 Mar 13;104(5):699-706. doi: 10.1161/CIRCRESAHA.108.189746. Epub 2009 Jan 24.

18.

Ultraviolet B radiation activates NF-κB and induces iNOS expression in HR-1 hairless mouse skin: role of IκB kinase-β.

Chang EJ, Kundu JK, Liu L, Shin JW, Surh YJ.

Mol Carcinog. 2011 Apr;50(4):310-7. doi: 10.1002/mc.20646.

PMID:
21465579
19.

Adiponectin-deficient mice are protected against tobacco-induced inflammation and increased emphysema.

Miller M, Pham A, Cho JY, Rosenthal P, Broide DH.

Am J Physiol Lung Cell Mol Physiol. 2010 Dec;299(6):L834-42. doi: 10.1152/ajplung.00326.2009. Epub 2010 Oct 8.

20.

Cigarette smoke induced airway inflammation is independent of NF-κB signalling.

Rastrick JM, Stevenson CS, Eltom S, Grace M, Davies M, Kilty I, Evans SM, Pasparakis M, Catley MC, Lawrence T, Adcock IM, Belvisi MG, Birrell MA.

PLoS One. 2013;8(1):e54128. doi: 10.1371/journal.pone.0054128. Epub 2013 Jan 22. Erratum in: PLoS One. 2013;8(10). doi:10.1371/annotation/754d7b19-2dac-479b-a23c-db9fed0431be.

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