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Items: 1 to 20 of 131

1.

A versatile synthetic approach toward diversity libraries using monosaccharide scaffolds.

Thanh GL, Abbenante G, Adamson G, Becker B, Clark C, Condie G, Falzun T, Grathwohl M, Gupta P, Hanson M, Huynh N, Katavic P, Kuipers K, Lam A, Liu L, Mann M, Mason J, McKeveney D, Muldoon C, Pearson A, Rajaratnam P, Ryan S, Tometzki G, Verquin G, Waanders J, West M, Wilcox N, Wimmer N, Yau A, Zuegg J, Meutermans W.

J Org Chem. 2010 Jan 1;75(1):197-203. doi: 10.1021/jo9021919.

PMID:
19961235
2.

Sugar amino acids and their uses in designing bioactive molecules.

Chakraborty TK, Ghosh S, Jayaprakash S.

Curr Med Chem. 2002 Feb;9(4):421-35. Review.

PMID:
11945118
4.

Sugar amino acid based scaffolds--novel peptidomimetics and their potential in combinatorial synthesis.

Chakraborty TK, Jayaprakash S, Ghosh S.

Comb Chem High Throughput Screen. 2002 Aug;5(5):373-87. Review.

PMID:
12180903
5.

Glycosamino acids: building blocks for combinatorial synthesis-implications for drug discovery.

Schweizer F.

Angew Chem Int Ed Engl. 2002 Jan 18;41(2):231-53. Review.

PMID:
12491402
6.

Molecular diversity through sugar scaffolds.

Le GT, Abbenante G, Becker B, Grathwohl M, Halliday J, Tometzki G, Zuegg J, Meutermans W.

Drug Discov Today. 2003 Aug 1;8(15):701-9. Review.

PMID:
12927513
7.
8.

Biological diversity from a structurally diverse library: systematically scanning conformational space using a pyranose scaffold.

Abbenante G, Becker B, Blanc S, Clark C, Condie G, Fraser G, Grathwohl M, Halliday J, Henderson S, Lam A, Liu L, Mann M, Muldoon C, Pearson A, Premraj R, Ramsdale T, Rossetti T, Schafer K, Le Thanh G, Tometzki G, Vari F, Verquin G, Waanders J, West M, Wimmer N, Yau A, Zuegg J, Meutermans W.

J Med Chem. 2010 Aug 12;53(15):5576-86. doi: 10.1021/jm1002777.

PMID:
20684600
9.

Optimization and visualization of molecular diversity of combinatorial libraries.

Hassan M, Bielawski JP, Hempel JC, Waldman M.

Mol Divers. 1996 Oct;2(1-2):64-74.

PMID:
9238635
11.

3-Azido-3-deoxy-glycopyranoside derivatives as scaffolds for the synthesis of carbohydrate-based universal pharmacophore mapping libraries.

Jain R, Kamau M, Wang C, Ippolito R, Wang H, Dulina R, Anderson J, Gange D, Sofia MJ.

Bioorg Med Chem Lett. 2003 Jul 7;13(13):2185-9.

PMID:
12798331
12.

Solid-phase synthetic route to multiple derivatives of a fundamental peptide unit.

Scott WL, Zhou Z, Zajdel P, Pawłowski M, O'Donnell MJ.

Molecules. 2010 Jul 20;15(7):4961-83. doi: 10.3390/molecules15074961.

13.

Molecular scaffold-based design and comparison of combinatorial libraries focused on the ATP-binding site of protein kinases.

Stahura FL, Xue L, Godden JW, Bajorath J.

J Mol Graph Model. 1999 Feb;17(1):1-9, 51-2.

PMID:
10660905
14.

Design of bioactive and structurally well-defined peptides from conformationally restricted libraries.

Pastor MT, Mora P, Ferrer-Montiel A, Pérez-Payá E.

Biopolymers. 2004;76(4):357-65.

PMID:
15386263
15.

Carbohydrates in peptide and protein design.

Jensen KJ, Brask J.

Biopolymers. 2005;80(6):747-61. Review.

PMID:
15929028
16.

Sugar amino acids in designing new molecules.

Chakraborty TK, Srinivasu P, Tapadar S, Mohan BK.

Glycoconj J. 2005 Mar;22(3):83-93. Review.

PMID:
16133829
17.

Design, docking, and evaluation of multiple libraries against multiple targets.

Lamb ML, Burdick KW, Toba S, Young MM, Skillman AG, Zou X, Arnold JR, Kuntz ID.

Proteins. 2001 Feb 15;42(3):296-318.

PMID:
11151003
18.

General inverse solid-phase synthesis method for C-terminally modified peptide mimetics.

Sasubilli R, Gutheil WG.

J Comb Chem. 2004 Nov-Dec;6(6):911-5.

PMID:
15530118
19.

A versatile synthetic approach to peptidyl privileged structures using a "safety-catch" linker.

Horton DA, Severinsen R, Kofod-Hansen M, Bourne GT, Smythe ML.

J Comb Chem. 2005 May-Jun;7(3):421-35.

PMID:
15877471
20.

Assessing the scaffold diversity of screening libraries.

Krier M, Bret G, Rognan D.

J Chem Inf Model. 2006 Mar-Apr;46(2):512-24.

PMID:
16562979
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