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Results: 1 to 20 of 103

1.

CB1 cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes.

Mukhopadhyay P, Rajesh M, Bátkai S, Patel V, Kashiwaya Y, Liaudet L, Evgenov OV, Mackie K, Haskó G, Pacher P.

Cardiovasc Res. 2010 Mar 1;85(4):773-84. doi: 10.1093/cvr/cvp369. Epub 2009 Nov 26.

PMID:
19942623
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Cannabinoid-1 receptor activation induces reactive oxygen species-dependent and -independent mitogen-activated protein kinase activation and cell death in human coronary artery endothelial cells.

Rajesh M, Mukhopadhyay P, Haskó G, Liaudet L, Mackie K, Pacher P.

Br J Pharmacol. 2010 Jun;160(3):688-700. doi: 10.1111/j.1476-5381.2010.00712.x.

PMID:
20590572
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Fatty acid amide hydrolase is a key regulator of endocannabinoid-induced myocardial tissue injury.

Mukhopadhyay P, Horváth B, Rajesh M, Matsumoto S, Saito K, Bátkai S, Patel V, Tanchian G, Gao RY, Cravatt BF, Haskó G, Pacher P.

Free Radic Biol Med. 2011 Jan 1;50(1):179-95. doi: 10.1016/j.freeradbiomed.2010.11.002. Epub 2010 Nov 9.

PMID:
21070851
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

CB1 cannabinoid receptors promote oxidative/nitrosative stress, inflammation and cell death in a murine nephropathy model.

Mukhopadhyay P, Pan H, Rajesh M, Bátkai S, Patel V, Harvey-White J, Mukhopadhyay B, Haskó G, Gao B, Mackie K, Pacher P.

Br J Pharmacol. 2010 Jun;160(3):657-68. doi: 10.1111/j.1476-5381.2010.00769.x.

PMID:
20590569
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Pharmacological inhibition of CB1 cannabinoid receptor protects against doxorubicin-induced cardiotoxicity.

Mukhopadhyay P, Bátkai S, Rajesh M, Czifra N, Harvey-White J, Haskó G, Zsengeller Z, Gerard NP, Liaudet L, Kunos G, Pacher P.

J Am Coll Cardiol. 2007 Aug 7;50(6):528-36. Epub 2007 Jul 23.

PMID:
17678736
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Cannabidiol attenuates cardiac dysfunction, oxidative stress, fibrosis, and inflammatory and cell death signaling pathways in diabetic cardiomyopathy.

Rajesh M, Mukhopadhyay P, Bátkai S, Patel V, Saito K, Matsumoto S, Kashiwaya Y, Horváth B, Mukhopadhyay B, Becker L, Haskó G, Liaudet L, Wink DA, Veves A, Mechoulam R, Pacher P.

J Am Coll Cardiol. 2010 Dec 14;56(25):2115-25. doi: 10.1016/j.jacc.2010.07.033.

PMID:
21144973
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Role of superoxide, nitric oxide, and peroxynitrite in doxorubicin-induced cell death in vivo and in vitro.

Mukhopadhyay P, Rajesh M, Bátkai S, Kashiwaya Y, Haskó G, Liaudet L, Szabó C, Pacher P.

Am J Physiol Heart Circ Physiol. 2009 May;296(5):H1466-83. doi: 10.1152/ajpheart.00795.2008. Epub 2009 Mar 13.

PMID:
19286953
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Davallialactone protects against adriamycin-induced cardiotoxicity in vitro and in vivo.

Arunachalam S, Kim SY, Lee SH, Lee YH, Kim MS, Yun BS, Yi HK, Hwang PH.

J Nat Med. 2012 Jan;66(1):149-57. doi: 10.1007/s11418-011-0567-1. Epub 2011 Aug 21.

PMID:
21858697
[PubMed - indexed for MEDLINE]
9.

Cannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathy.

Rajesh M, Bátkai S, Kechrid M, Mukhopadhyay P, Lee WS, Horváth B, Holovac E, Cinar R, Liaudet L, Mackie K, Haskó G, Pacher P.

Diabetes. 2012 Mar;61(3):716-27. doi: 10.2337/db11-0477. Epub 2012 Feb 7.

PMID:
22315315
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Cannabinoid 1 receptor activation contributes to vascular inflammation and cell death in a mouse model of diabetic retinopathy and a human retinal cell line.

El-Remessy AB, Rajesh M, Mukhopadhyay P, Horváth B, Patel V, Al-Gayyar MM, Pillai BA, Pacher P.

Diabetologia. 2011 Jun;54(6):1567-78. doi: 10.1007/s00125-011-2061-4. Epub 2011 Mar 4.

PMID:
21373835
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The endocannabinoid anandamide induces apoptosis of rat decidual cells through a mechanism involving ceramide synthesis and p38 MAPK activation.

Fonseca BM, Correia-da-Silva G, Teixeira NA.

Apoptosis. 2013 Dec;18(12):1526-35. doi: 10.1007/s10495-013-0892-9.

PMID:
24048885
[PubMed - indexed for MEDLINE]
12.

Ghrelin inhibits doxorubicin cardiotoxicity by inhibiting excessive autophagy through AMPK and p38-MAPK.

Wang X, Wang XL, Chen HL, Wu D, Chen JX, Wang XX, Li RL, He JH, Mo L, Cen X, Wei YQ, Jiang W.

Biochem Pharmacol. 2014 Apr 1;88(3):334-50. doi: 10.1016/j.bcp.2014.01.040. Epub 2014 Feb 9.

PMID:
24522112
[PubMed - indexed for MEDLINE]
13.

Erythropoietin protects against doxorubicin-induced cardiomyopathy via a phosphatidylinositol 3-kinase-dependent pathway.

Kim KH, Oudit GY, Backx PH.

J Pharmacol Exp Ther. 2008 Jan;324(1):160-9. Epub 2007 Oct 10.

PMID:
17928571
[PubMed - indexed for MEDLINE]
Free Article
14.

Taurine prevents arsenic-induced cardiac oxidative stress and apoptotic damage: role of NF-kappa B, p38 and JNK MAPK pathway.

Ghosh J, Das J, Manna P, Sil PC.

Toxicol Appl Pharmacol. 2009 Oct 1;240(1):73-87. doi: 10.1016/j.taap.2009.07.008. Epub 2009 Jul 17.

PMID:
19616567
[PubMed - indexed for MEDLINE]
15.

Absence of thrombospondin-2 increases cardiomyocyte damage and matrix disruption in doxorubicin-induced cardiomyopathy.

van Almen GC, Swinnen M, Carai P, Verhesen W, Cleutjens JP, D'hooge J, Verheyen FK, Pinto YM, Schroen B, Carmeliet P, Heymans S.

J Mol Cell Cardiol. 2011 Sep;51(3):318-28. doi: 10.1016/j.yjmcc.2011.05.010. Epub 2011 May 23.

PMID:
21624372
[PubMed - indexed for MEDLINE]
16.

Heat shock protein 20 interacting with phosphorylated Akt reduces doxorubicin-triggered oxidative stress and cardiotoxicity.

Fan GC, Zhou X, Wang X, Song G, Qian J, Nicolaou P, Chen G, Ren X, Kranias EG.

Circ Res. 2008 Nov 21;103(11):1270-9. doi: 10.1161/CIRCRESAHA.108.182832. Epub 2008 Oct 23.

PMID:
18948619
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Subcellular basis of vitamin C protection against doxorubicin-induced changes in rat cardiomyocytes.

Ludke A, Sharma AK, Bagchi AK, Singal PK.

Mol Cell Biochem. 2012 Jan;360(1-2):215-24. doi: 10.1007/s11010-011-1059-z. Epub 2011 Sep 22.

PMID:
21938406
[PubMed - indexed for MEDLINE]
18.

Manipulation of cardiac phosphatidylinositol 3-kinase (PI3K)/Akt signaling by apoptosis regulator through modulating IAP expression (ARIA) regulates cardiomyocyte death during doxorubicin-induced cardiomyopathy.

Kitamura Y, Koide M, Akakabe Y, Matsuo K, Shimoda Y, Soma Y, Ogata T, Ueyama T, Matoba S, Yamada H, Ikeda K.

J Biol Chem. 2014 Jan 31;289(5):2788-800. doi: 10.1074/jbc.M113.508143. Epub 2013 Dec 13.

PMID:
24338479
[PubMed - indexed for MEDLINE]
19.

N-acetylcysteine amide decreases oxidative stress but not cell death induced by doxorubicin in H9c2 cardiomyocytes.

Shi R, Huang CC, Aronstam RS, Ercal N, Martin A, Huang YW.

BMC Pharmacol. 2009 Apr 15;9:7. doi: 10.1186/1471-2210-9-7.

PMID:
19368719
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Cadmium induces apoptosis in pancreatic β-cells through a mitochondria-dependent pathway: the role of oxidative stress-mediated c-Jun N-terminal kinase activation.

Chang KC, Hsu CC, Liu SH, Su CC, Yen CC, Lee MJ, Chen KL, Ho TJ, Hung DZ, Wu CC, Lu TH, Su YC, Chen YW, Huang CF.

PLoS One. 2013;8(2):e54374. doi: 10.1371/journal.pone.0054374. Epub 2013 Feb 6.

PMID:
23405080
[PubMed - indexed for MEDLINE]
Free PMC Article

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