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Items: 1 to 20 of 307

1.

CCK activates RhoA and Rac1 differentially through Galpha13 and Galphaq in mouse pancreatic acini.

Sabbatini ME, Bi Y, Ji B, Ernst SA, Williams JA.

Am J Physiol Cell Physiol. 2010 Mar;298(3):C592-601. doi: 10.1152/ajpcell.00448.2009. Epub 2009 Nov 25.

2.

G12/13 and Gq mediate S1P2-induced inhibition of Rac and migration in vascular smooth muscle in a manner dependent on Rho but not Rho kinase.

Takashima S, Sugimoto N, Takuwa N, Okamoto Y, Yoshioka K, Takamura M, Takata S, Kaneko S, Takuwa Y.

Cardiovasc Res. 2008 Sep 1;79(4):689-97. doi: 10.1093/cvr/cvn118. Epub 2008 May 14.

3.

Rho and Rac promote acinar morphological changes, actin reorganization, and amylase secretion.

Bi Y, Page SL, Williams JA.

Am J Physiol Gastrointest Liver Physiol. 2005 Sep;289(3):G561-70. Epub 2005 May 26.

4.
5.

Galpha(12/13) mediates alpha(1)-adrenergic receptor-induced cardiac hypertrophy.

Maruyama Y, Nishida M, Sugimoto Y, Tanabe S, Turner JH, Kozasa T, Wada T, Nagao T, Kurose H.

Circ Res. 2002 Nov 15;91(10):961-9.

6.

Pasteurella multocida toxin-induced activation of RhoA is mediated via two families of G{alpha} proteins, G{alpha}q and G{alpha}12/13.

Orth JH, Lang S, Taniguchi M, Aktories K.

J Biol Chem. 2005 Nov 4;280(44):36701-7. Epub 2005 Sep 1.

7.

Involvement of RhoA and its interaction with protein kinase C and Src in CCK-stimulated pancreatic acini.

Nozu F, Tsunoda Y, Ibitayo AI, Bitar KN, Owyang C.

Am J Physiol. 1999 Apr;276(4 Pt 1):G915-23.

8.

Receptor-dependent RhoA activation in G12/G13-deficient cells: genetic evidence for an involvement of Gq/G11.

Vogt S, Grosse R, Schultz G, Offermanns S.

J Biol Chem. 2003 Aug 1;278(31):28743-9. Epub 2003 May 27.

9.

CCK-A receptor activates RhoA through G alpha 12/13 in NIH3T3 cells.

Le Page SL, Bi Y, Williams JA.

Am J Physiol Cell Physiol. 2003 Nov;285(5):C1197-206. Epub 2003 Jul 9.

10.
11.

Activation of p115-RhoGEF requires direct association of Gα13 and the Dbl homology domain.

Chen Z, Guo L, Hadas J, Gutowski S, Sprang SR, Sternweis PC.

J Biol Chem. 2012 Jul 20;287(30):25490-500. doi: 10.1074/jbc.M111.333716. Epub 2012 Jun 1.

12.

Radixin stimulates Rac1 and Ca2+/calmodulin-dependent kinase, CaMKII: cross-talk with Galpha13 signaling.

Liu G, Voyno-Yasenetskaya TA.

J Biol Chem. 2005 Nov 25;280(47):39042-9. Epub 2005 Sep 26.

13.

A role for Rho and Rac in secretagogue-induced amylase release by pancreatic acini.

Bi Y, Williams JA.

Am J Physiol Cell Physiol. 2005 Jul;289(1):C22-32. Epub 2005 Mar 2.

14.

Galpha12/13-mediated production of reactive oxygen species is critical for angiotensin receptor-induced NFAT activation in cardiac fibroblasts.

Fujii T, Onohara N, Maruyama Y, Tanabe S, Kobayashi H, Fukutomi M, Nagamatsu Y, Nishihara N, Inoue R, Sumimoto H, Shibasaki F, Nagao T, Nishida M, Kurose H.

J Biol Chem. 2005 Jun 17;280(24):23041-7. Epub 2005 Apr 12.

15.

PDZ-RhoGEF and LARG are essential for embryonic development and provide a link between thrombin and LPA receptors and Rho activation.

Mikelis CM, Palmby TR, Simaan M, Li W, Szabo R, Lyons R, Martin D, Yagi H, Fukuhara S, Chikumi H, Galisteo R, Mukouyama YS, Bugge TH, Gutkind JS.

J Biol Chem. 2013 Apr 26;288(17):12232-43. doi: 10.1074/jbc.M112.428599. Epub 2013 Mar 6.

16.

Rap1 activation plays a regulatory role in pancreatic amylase secretion.

Sabbatini ME, Chen X, Ernst SA, Williams JA.

J Biol Chem. 2008 Aug 29;283(35):23884-94. doi: 10.1074/jbc.M800754200. Epub 2008 Jun 24.

17.

Cholecystokinin stimulates the recruitment of the Src-RhoA-phosphoinositide 3-kinase pathway by Vav-2 downstream of G(alpha13) in pancreatic acini.

Kim M, Nozu F, Kusama K, Imawari M.

Biochem Biophys Res Commun. 2006 Jan 6;339(1):271-6. Epub 2005 Nov 10.

PMID:
16297869
18.

Selective regulation of Galpha(q/11) by an RGS domain in the G protein-coupled receptor kinase, GRK2.

Carman CV, Parent JL, Day PW, Pronin AN, Sternweis PM, Wedegaertner PB, Gilman AG, Benovic JL, Kozasa T.

J Biol Chem. 1999 Nov 26;274(48):34483-92.

19.

A role for the p38 mitogen-activated protein kinase/Hsp 27 pathway in cholecystokinin-induced changes in the actin cytoskeleton in rat pancreatic acini.

Schäfer C, Ross SE, Bragado MJ, Groblewski GE, Ernst SA, Williams JA.

J Biol Chem. 1998 Sep 11;273(37):24173-80.

20.

Activation of RhoA by association of Galpha(13) with Dbl.

Jin S, Exton JH.

Biochem Biophys Res Commun. 2000 Nov 2;277(3):718-21.

PMID:
11062019
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