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Results: 1 to 20 of 103

1.

The hyperforin derivative IDN5706 occludes spatial memory impairments and neuropathological changes in a double transgenic Alzheimer's mouse model.

Cerpa W, Hancke JL, Morazzoni P, Bombardelli E, Riva A, Marin PP, Inestrosa NC.

Curr Alzheimer Res. 2010 Mar;7(2):126-33.

PMID:
19939230
[PubMed - indexed for MEDLINE]
2.

Hyperforin prevents beta-amyloid neurotoxicity and spatial memory impairments by disaggregation of Alzheimer's amyloid-beta-deposits.

Dinamarca MC, Cerpa W, Garrido J, Hancke JL, Inestrosa NC.

Mol Psychiatry. 2006 Nov;11(11):1032-48. Epub 2006 Jul 25.

PMID:
16880827
[PubMed - indexed for MEDLINE]
3.

Tetrahydrohyperforin prevents cognitive deficit, Aβ deposition, tau phosphorylation and synaptotoxicity in the APPswe/PSEN1ΔE9 model of Alzheimer's disease: a possible effect on APP processing.

Inestrosa NC, Tapia-Rojas C, Griffith TN, Carvajal FJ, Benito MJ, Rivera-Dictter A, Alvarez AR, Serrano FG, Hancke JL, Burgos PV, Parodi J, Varela-Nallar L.

Transl Psychiatry. 2011 Jul 12;1:e20. doi: 10.1038/tp.2011.19.

PMID:
22832522
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Tetrahydrohyperforin increases adult hippocampal neurogenesis in wild-type and APPswe/PS1ΔE9 mice.

Abbott AC, Calderon Toledo C, Aranguiz FC, Inestrosa NC, Varela-Nallar L.

J Alzheimers Dis. 2013;34(4):873-85. doi: 10.3233/JAD-121714.

PMID:
23302657
[PubMed - indexed for MEDLINE]
5.

Hydrogen-rich saline improves memory function in a rat model of amyloid-beta-induced Alzheimer's disease by reduction of oxidative stress.

Li J, Wang C, Zhang JH, Cai JM, Cao YP, Sun XJ.

Brain Res. 2010 Apr 30;1328:152-61. doi: 10.1016/j.brainres.2010.02.046. Epub 2010 Feb 19.

PMID:
20171955
[PubMed - indexed for MEDLINE]
6.

Neurobiological effects of Hyperforin and its potential in Alzheimer's disease therapy.

Griffith TN, Varela-Nallar L, Dinamarca MC, Inestrosa NC.

Curr Med Chem. 2010;17(5):391-406. Review.

PMID:
20015041
[PubMed - indexed for MEDLINE]
7.

Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1DeltaE9 mouse model of Alzheimer's disease.

Toledo EM, Inestrosa NC.

Mol Psychiatry. 2010 Mar;15(3):272-85, 228. doi: 10.1038/mp.2009.72. Epub 2009 Jul 21.

PMID:
19621015
[PubMed - indexed for MEDLINE]
8.

Indirubin-3'-monoxime rescues spatial memory deficits and attenuates beta-amyloid-associated neuropathology in a mouse model of Alzheimer's disease.

Ding Y, Qiao A, Fan GH.

Neurobiol Dis. 2010 Aug;39(2):156-68. doi: 10.1016/j.nbd.2010.03.022. Epub 2010 Apr 8.

PMID:
20381617
[PubMed - indexed for MEDLINE]
9.

Reduced Alzheimer's disease pathology by St. John's Wort treatment is independent of hyperforin and facilitated by ABCC1 and microglia activation in mice.

Hofrichter J, Krohn M, Schumacher T, Lange C, Feistel B, Walbroel B, Heinze HJ, Crockett S, Sharbel TF, Pahnke J.

Curr Alzheimer Res. 2013 Dec;10(10):1057-69.

PMID:
24156265
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

A novel recombinant adeno-associated virus vaccine reduces behavioral impairment and beta-amyloid plaques in a mouse model of Alzheimer's disease.

Zhang J, Wu X, Qin C, Qi J, Ma S, Zhang H, Kong Q, Chen D, Ba D, He W.

Neurobiol Dis. 2003 Dec;14(3):365-79.

PMID:
14678754
[PubMed - indexed for MEDLINE]
11.

M1 muscarinic agonists can modulate some of the hallmarks in Alzheimer's disease: implications in future therapy.

Fisher A, Pittel Z, Haring R, Bar-Ner N, Kliger-Spatz M, Natan N, Egozi I, Sonego H, Marcovitch I, Brandeis R.

J Mol Neurosci. 2003;20(3):349-56. Review.

PMID:
14501019
[PubMed - indexed for MEDLINE]
12.

Effects of memantine on soluble Alphabeta(25-35)-induced changes in peptidergic and glial cells in Alzheimer's disease model rat brain regions.

Arif M, Chikuma T, Ahmed MM, Nakazato M, Smith MA, Kato T.

Neuroscience. 2009 Dec 15;164(3):1199-209. doi: 10.1016/j.neuroscience.2009.08.063. Epub 2009 Sep 4.

PMID:
19733635
[PubMed - indexed for MEDLINE]
13.

Tetrahydrohyperforin decreases cholinergic markers associated with amyloid-β plaques, 4-hydroxynonenal formation, and caspase-3 activation in AβPP/PS1 mice.

Carvajal FJ, Zolezzi JM, Tapia-Rojas C, Godoy JA, Inestrosa NC.

J Alzheimers Dis. 2013;36(1):99-118. doi: 10.3233/JAD-130230.

PMID:
23568104
[PubMed - indexed for MEDLINE]
14.

Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities.

Savonenko A, Xu GM, Melnikova T, Morton JL, Gonzales V, Wong MP, Price DL, Tang F, Markowska AL, Borchelt DR.

Neurobiol Dis. 2005 Apr;18(3):602-17.

PMID:
15755686
[PubMed - indexed for MEDLINE]
15.

S14G-humanin improves cognitive deficits and reduces amyloid pathology in the middle-aged APPswe/PS1dE9 mice.

Zhang W, Zhang W, Li Z, Hao J, Zhang Z, Liu L, Mao N, Miao J, Zhang L.

Pharmacol Biochem Behav. 2012 Jan;100(3):361-9. doi: 10.1016/j.pbb.2011.09.012. Epub 2011 Oct 2.

PMID:
21993310
[PubMed - indexed for MEDLINE]
16.

Prevention of age-related spatial memory deficits in a transgenic mouse model of Alzheimer's disease by chronic Ginkgo biloba treatment.

Stackman RW, Eckenstein F, Frei B, Kulhanek D, Nowlin J, Quinn JF.

Exp Neurol. 2003 Nov;184(1):510-20.

PMID:
14637120
[PubMed - indexed for MEDLINE]
17.

Effect of synthetic cannabinoid HU210 on memory deficits and neuropathology in Alzheimer's disease mouse model.

Chen B, Bromley-Brits K, He G, Cai F, Zhang X, Song W.

Curr Alzheimer Res. 2010 May;7(3):255-61.

PMID:
20043809
[PubMed - indexed for MEDLINE]
18.

Antisense directed at the Abeta region of APP decreases brain oxidative markers in aged senescence accelerated mice.

Poon HF, Joshi G, Sultana R, Farr SA, Banks WA, Morley JE, Calabrese V, Butterfield DA.

Brain Res. 2004 Aug 20;1018(1):86-96.

PMID:
15262209
[PubMed - indexed for MEDLINE]
19.

Release of acetylcholinesterase (AChE) from beta-amyloid plaques assemblies improves the spatial memory impairments in APP-transgenic mice.

Dinamarca MC, Arrázola M, Toledo E, Cerpa WF, Hancke J, Inestrosa NC.

Chem Biol Interact. 2008 Sep 25;175(1-3):142-9. doi: 10.1016/j.cbi.2008.05.026. Epub 2008 May 27.

PMID:
18599028
[PubMed - indexed for MEDLINE]
20.

Chronic administration of R-flurbiprofen attenuates learning impairments in transgenic amyloid precursor protein mice.

Kukar T, Prescott S, Eriksen JL, Holloway V, Murphy MP, Koo EH, Golde TE, Nicolle MM.

BMC Neurosci. 2007 Jul 24;8:54.

PMID:
17650315
[PubMed - indexed for MEDLINE]
Free PMC Article

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