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Items: 1 to 20 of 294

1.

Inhibition of Akt signaling by the lignan matairesinol sensitizes prostate cancer cells to TRAIL-induced apoptosis.

Peuhu E, Rivero-Müller A, Stykki H, Torvaldson E, Holmbom T, Eklund P, Unkila M, Sjöholm R, Eriksson JE.

Oncogene. 2010 Feb 11;29(6):898-908. doi: 10.1038/onc.2009.386. Epub 2009 Nov 23.

PMID:
19935713
3.

The antitumor lignan Nortrachelogenin sensitizes prostate cancer cells to TRAIL-induced cell death by inhibition of the Akt pathway and growth factor signaling.

Peuhu E, Paul P, Remes M, Holmbom T, Eklund P, Sjöholm R, Eriksson JE.

Biochem Pharmacol. 2013 Sep 1;86(5):571-83. doi: 10.1016/j.bcp.2013.05.026. Epub 2013 Jun 6.

PMID:
23747345
4.
5.

Sensitivity of prostate cells to TRAIL-induced apoptosis increases with tumor progression: DR5 and caspase 8 are key players.

Hesry V, Piquet-Pellorce C, Travert M, Donaghy L, Jégou B, Patard JJ, Guillaudeux T.

Prostate. 2006 Jun 15;66(9):987-95.

PMID:
16541419
7.

The alkylphospholipid perifosine induces apoptosis of human lung cancer cells requiring inhibition of Akt and activation of the extrinsic apoptotic pathway.

Elrod HA, Lin YD, Yue P, Wang X, Lonial S, Khuri FR, Sun SY.

Mol Cancer Ther. 2007 Jul;6(7):2029-38. Epub 2007 Jun 29.

8.

Roscovitine sensitizes breast cancer cells to TRAIL-induced apoptosis through a pleiotropic mechanism.

Ortiz-Ferrón G, Yerbes R, Eramo A, López-Pérez AI, De Maria R, López-Rivas A.

Cell Res. 2008 Jun;18(6):664-76. doi: 10.1038/cr.2008.54.

9.

Imatinib enhances human melanoma cell susceptibility to TRAIL-induced cell death: Relationship to Bcl-2 family and caspase activation.

Hamaï A, Richon C, Meslin F, Faure F, Kauffmann A, Lecluse Y, Jalil A, Larue L, Avril MF, Chouaib S, Mehrpour M.

Oncogene. 2006 Dec 7;25(58):7618-34. Epub 2006 Sep 18. Erratum in: Oncogene. 2007 Feb 22;26(8):1256.

PMID:
16983347
10.

Anti-gout agent allopurinol exerts cytotoxicity to human hormone-refractory prostate cancer cells in combination with tumor necrosis factor-related apoptosis-inducing ligand.

Yasuda T, Yoshida T, Goda AE, Horinaka M, Yano K, Shiraishi T, Wakada M, Mizutani Y, Miki T, Sakai T.

Mol Cancer Res. 2008 Dec;6(12):1852-60. doi: 10.1158/1541-7786.MCR-08-0012.

11.

TRAIL apoptosis is enhanced by quercetin through Akt dephosphorylation.

Kim YH, Lee YJ.

J Cell Biochem. 2007 Mar 1;100(4):998-1009.

PMID:
17031854
12.

Quercetin enhances TRAIL-mediated apoptosis in colon cancer cells by inducing the accumulation of death receptors in lipid rafts.

Psahoulia FH, Drosopoulos KG, Doubravska L, Andera L, Pintzas A.

Mol Cancer Ther. 2007 Sep;6(9):2591-9.

13.

FOXO3a mediates the androgen-dependent regulation of FLIP and contributes to TRAIL-induced apoptosis of LNCaP cells.

Cornforth AN, Davis JS, Khanifar E, Nastiuk KL, Krolewski JJ.

Oncogene. 2008 Jul 24;27(32):4422-33. doi: 10.1038/onc.2008.80. Epub 2008 Apr 7.

PMID:
18391984
14.

Elevated AKT activity protects the prostate cancer cell line LNCaP from TRAIL-induced apoptosis.

Nesterov A, Lu X, Johnson M, Miller GJ, Ivashchenko Y, Kraft AS.

J Biol Chem. 2001 Apr 6;276(14):10767-74. Epub 2001 Jan 18.

15.

Upregulation of FLIP(S) by Akt, a possible inhibition mechanism of TRAIL-induced apoptosis in human gastric cancers.

Nam SY, Jung GA, Hur GC, Chung HY, Kim WH, Seol DW, Lee BL.

Cancer Sci. 2003 Dec;94(12):1066-73.

16.

Tunicamycin enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human prostate cancer cells.

Shiraishi T, Yoshida T, Nakata S, Horinaka M, Wakada M, Mizutani Y, Miki T, Sakai T.

Cancer Res. 2005 Jul 15;65(14):6364-70.

17.

Proteasome inhibition sensitizes hepatocellular carcinoma cells to TRAIL by suppressing caspase inhibitors and AKT pathway.

Inoue T, Shiraki K, Fuke H, Yamanaka Y, Miyashita K, Yamaguchi Y, Yamamoto N, Ito K, Sugimoto K, Nakano T.

Anticancer Drugs. 2006 Mar;17(3):261-8.

PMID:
16520654
18.

Sanguinarine sensitizes human gastric adenocarcinoma AGS cells to TRAIL-mediated apoptosis via down-regulation of AKT and activation of caspase-3.

Choi WY, Jin CY, Han MH, Kim GY, Kim ND, Lee WH, Kim SK, Choi YH.

Anticancer Res. 2009 Nov;29(11):4457-65.

19.

Subtoxic concentration of doxorubicin enhances TRAIL-induced apoptosis in human prostate cancer cell line LNCaP.

Kang J, Bu J, Hao Y, Chen F.

Prostate Cancer Prostatic Dis. 2005;8(3):274-9.

PMID:
15897917
20.

Protein kinase C modulates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by targeting the apical events of death receptor signaling.

Harper N, Hughes MA, Farrow SN, Cohen GM, MacFarlane M.

J Biol Chem. 2003 Nov 7;278(45):44338-47. Epub 2003 Aug 14.

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