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Items: 1 to 20 of 100

1.

The integrin alpha4beta7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1.

Cicala C, Martinelli E, McNally JP, Goode DJ, Gopaul R, Hiatt J, Jelicic K, Kottilil S, Macleod K, O'Shea A, Patel N, Van Ryk D, Wei D, Pascuccio M, Yi L, McKinnon L, Izulla P, Kimani J, Kaul R, Fauci AS, Arthos J.

Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20877-82. doi: 10.1073/pnas.0911796106. Epub 2009 Nov 20.

2.

Transmitted/founder and chronic subtype C HIV-1 use CD4 and CCR5 receptors with equal efficiency and are not inhibited by blocking the integrin α4β7.

Parrish NF, Wilen CB, Banks LB, Iyer SS, Pfaff JM, Salazar-Gonzalez JF, Salazar MG, Decker JM, Parrish EH, Berg A, Hopper J, Hora B, Kumar A, Mahlokozera T, Yuan S, Coleman C, Vermeulen M, Ding H, Ochsenbauer C, Tilton JC, Permar SR, Kappes JC, Betts MR, Busch MP, Gao F, Montefiori D, Haynes BF, Shaw GM, Hahn BH, Doms RW.

PLoS Pathog. 2012;8(5):e1002686. doi: 10.1371/journal.ppat.1002686. Epub 2012 May 31.

3.

Characterization of a human cervical CD4+ T cell subset coexpressing multiple markers of HIV susceptibility.

McKinnon LR, Nyanga B, Chege D, Izulla P, Kimani M, Huibner S, Gelmon L, Block KE, Cicala C, Anzala AO, Arthos J, Kimani J, Kaul R.

J Immunol. 2011 Dec 1;187(11):6032-42. doi: 10.4049/jimmunol.1101836. Epub 2011 Nov 2.

4.

HIV-1 envelope, integrins and co-receptor use in mucosal transmission of HIV.

Cicala C, Arthos J, Fauci AS.

J Transl Med. 2011 Jan 27;9 Suppl 1:S2. doi: 10.1186/1479-5876-9-S1-S2. Review.

5.

Identification of a CCR5-expressing T cell subset that is resistant to R5-tropic HIV infection.

Oswald-Richter K, Grill SM, Leelawong M, Tseng M, Kalams SA, Hulgan T, Haas DW, Unutmaz D.

PLoS Pathog. 2007 Apr;3(4):e58.

6.

Infection of CD127+ (interleukin-7 receptor+) CD4+ cells and overexpression of CTLA-4 are linked to loss of antigen-specific CD4 T cells during primary human immunodeficiency virus type 1 infection.

Zaunders JJ, Ip S, Munier ML, Kaufmann DE, Suzuki K, Brereton C, Sasson SC, Seddiki N, Koelsch K, Landay A, Grey P, Finlayson R, Kaldor J, Rosenberg ES, Walker BD, Fazekas de St Groth B, Cooper DA, Kelleher AD.

J Virol. 2006 Oct;80(20):10162-72.

7.

Memory CCR6+CD4+ T cells are preferential targets for productive HIV type 1 infection regardless of their expression of integrin β7.

Monteiro P, Gosselin A, Wacleche VS, El-Far M, Said EA, Kared H, Grandvaux N, Boulassel MR, Routy JP, Ancuta P.

J Immunol. 2011 Apr 15;186(8):4618-30. doi: 10.4049/jimmunol.1004151. Epub 2011 Mar 11.

8.

HIV-1 envelope protein binds to and signals through integrin alpha4beta7, the gut mucosal homing receptor for peripheral T cells.

Arthos J, Cicala C, Martinelli E, Macleod K, Van Ryk D, Wei D, Xiao Z, Veenstra TD, Conrad TP, Lempicki RA, McLaughlin S, Pascuccio M, Gopaul R, McNally J, Cruz CC, Censoplano N, Chung E, Reitano KN, Kottilil S, Goode DJ, Fauci AS.

Nat Immunol. 2008 Mar;9(3):301-9. doi: 10.1038/ni1566. Epub 2008 Feb 10.

PMID:
18264102
9.

Replication of M-tropic HIV-1 in activated human intestinal lamina propria lymphocytes is the main reason for increased virus load in the intestinal mucosa.

Aziz S, Fackler OT, Meyerhans A, Müller-Lantzsch N, Zeitz M, Schneider T.

J Acquir Immune Defic Syndr. 2005 Jan 1;38(1):23-30.

PMID:
15608520
10.

Follicular dendritic cell-mediated up-regulation of CXCR4 expression on CD4 T cells and HIV pathogenesis.

Estes JD, Keele BF, Tenner-Racz K, Racz P, Redd MA, Thacker TC, Jiang Y, Lloyd MJ, Gartner S, Burton GF.

J Immunol. 2002 Sep 1;169(5):2313-22.

11.

Differential susceptibility of naïve, central memory and effector memory T cells to dendritic cell-mediated HIV-1 transmission.

Groot F, van Capel TM, Schuitemaker J, Berkhout B, de Jong EC.

Retrovirology. 2006 Aug 17;3:52.

12.

The potential impact of CD4+ T cell activation and enhanced Th1/Th2 cytokine ratio on HIV-1 secretion in the lungs of individuals with advanced AIDS and active pulmonary infection.

Rubbo PA, Tuaillon E, Bolloré K, Foulongne V, Bourdin A, Nagot N, Van de Perre P, Desgranges C, Israël-Biet D, Vendrell JP.

Clin Immunol. 2011 May;139(2):142-54. doi: 10.1016/j.clim.2011.01.007. Epub 2011 Jan 27.

PMID:
21345739
13.

Altered CD4+ T cell homing to the gut impairs mucosal immune reconstitution in treated HIV-infected individuals.

Mavigner M, Cazabat M, Dubois M, L'Faqihi FE, Requena M, Pasquier C, Klopp P, Amar J, Alric L, Barange K, Vinel JP, Marchou B, Massip P, Izopet J, Delobel P.

J Clin Invest. 2012 Jan;122(1):62-9. doi: 10.1172/JCI59011. Epub 2011 Dec 12.

14.

A single HIV-1 cluster and a skewed immune homeostasis drive the early spread of HIV among resting CD4+ cell subsets within one month post-infection.

Bacchus C, Cheret A, Avettand-Fenoël V, Nembot G, Mélard A, Blanc C, Lascoux-Combe C, Slama L, Allegre T, Allavena C, Yazdanpanah Y, Duvivier C, Katlama C, Goujard C, Seksik BC, Leplatois A, Molina JM, Meyer L, Autran B, Rouzioux C; OPTIPRIM ANRS 147 study group.

PLoS One. 2013 May 14;8(5):e64219. doi: 10.1371/journal.pone.0064219. Print 2013.

15.

Downregulation of CCR5 on activated CD4 T cells in HIV-infected Indians.

Dubey S, Khalid M, Wesley C, Khan SA, Wanchu A, Jameel S.

J Clin Virol. 2008 Sep;43(1):25-31. doi: 10.1016/j.jcv.2008.03.026. Epub 2008 May 6.

PMID:
18462992
16.

Selective loss of innate CD4(+) V alpha 24 natural killer T cells in human immunodeficiency virus infection.

Sandberg JK, Fast NM, Palacios EH, Fennelly G, Dobroszycki J, Palumbo P, Wiznia A, Grant RM, Bhardwaj N, Rosenberg MG, Nixon DF.

J Virol. 2002 Aug;76(15):7528-34.

17.

Primary human mammary epithelial cells endocytose HIV-1 and facilitate viral infection of CD4+ T lymphocytes.

Dorosko SM, Connor RI.

J Virol. 2010 Oct;84(20):10533-42. doi: 10.1128/JVI.01263-10. Epub 2010 Aug 11.

18.

Inhibition of HIV-1 infection by human α-defensin-5, a natural antimicrobial peptide expressed in the genital and intestinal mucosae.

Furci L, Tolazzi M, Sironi F, Vassena L, Lusso P.

PLoS One. 2012;7(9):e45208. doi: 10.1371/journal.pone.0045208. Epub 2012 Sep 27.

19.

CD127 and CD25 expression defines CD4+ T cell subsets that are differentially depleted during HIV infection.

Dunham RM, Cervasi B, Brenchley JM, Albrecht H, Weintrob A, Sumpter B, Engram J, Gordon S, Klatt NR, Frank I, Sodora DL, Douek DC, Paiardini M, Silvestri G.

J Immunol. 2008 Apr 15;180(8):5582-92.

20.

Adenovirus vector vaccination induces expansion of memory CD4 T cells with a mucosal homing phenotype that are readily susceptible to HIV-1.

Benlahrech A, Harris J, Meiser A, Papagatsias T, Hornig J, Hayes P, Lieber A, Athanasopoulos T, Bachy V, Csomor E, Daniels R, Fisher K, Gotch F, Seymour L, Logan K, Barbagallo R, Klavinskis L, Dickson G, Patterson S.

Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19940-5. doi: 10.1073/pnas.0907898106. Epub 2009 Nov 16.

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