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Items: 1 to 20 of 169

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Structural insight into nascent polypeptide chain-mediated translational stalling.

Seidelt B, Innis CA, Wilson DN, Gartmann M, Armache JP, Villa E, Trabuco LG, Becker T, Mielke T, Schulten K, Steitz TA, Beckmann R.

Science. 2009 Dec 4;326(5958):1412-5. doi: 10.1126/science.1177662. Epub 2009 Oct 29.


23S rRNA nucleotides in the peptidyl transferase center are essential for tryptophanase operon induction.

Yang R, Cruz-Vera LR, Yanofsky C.

J Bacteriol. 2009 Jun;191(11):3445-50. doi: 10.1128/JB.00096-09. Epub 2009 Mar 27.


Features of ribosome-peptidyl-tRNA interactions essential for tryptophan induction of tna operon expression.

Cruz-Vera LR, Rajagopal S, Squires C, Yanofsky C.

Mol Cell. 2005 Aug 5;19(3):333-43.


Instruction of translating ribosome by nascent peptide.

Gong F, Yanofsky C.

Science. 2002 Sep 13;297(5588):1864-7.


Molecular basis for the ribosome functioning as an L-tryptophan sensor.

Bischoff L, Berninghausen O, Beckmann R.

Cell Rep. 2014 Oct 23;9(2):469-75. doi: 10.1016/j.celrep.2014.09.011. Epub 2014 Oct 9.


Ribosomal features essential for tna operon induction: tryptophan binding at the peptidyl transferase center.

Cruz-Vera LR, New A, Squires C, Yanofsky C.

J Bacteriol. 2007 Apr;189(8):3140-6. Epub 2007 Feb 9.


SecM-stalled ribosomes adopt an altered geometry at the peptidyl transferase center.

Bhushan S, Hoffmann T, Seidelt B, Frauenfeld J, Mielke T, Berninghausen O, Wilson DN, Beckmann R.

PLoS Biol. 2011 Jan 18;9(1):e1000581. doi: 10.1371/journal.pbio.1000581.


Changes produced by bound tryptophan in the ribosome peptidyl transferase center in response to TnaC, a nascent leader peptide.

Cruz-Vera LR, Gong M, Yanofsky C.

Proc Natl Acad Sci U S A. 2006 Mar 7;103(10):3598-603. Epub 2006 Feb 27.


Recognition of the regulatory nascent chain TnaC by the ribosome.

Trabuco LG, Harrison CB, Schreiner E, Schulten K.

Structure. 2010 May 12;18(5):627-37. doi: 10.1016/j.str.2010.02.011.


Mechanisms of SecM-mediated stalling in the ribosome.

Gumbart J, Schreiner E, Wilson DN, Beckmann R, Schulten K.

Biophys J. 2012 Jul 18;103(2):331-41. doi: 10.1016/j.bpj.2012.06.005. Epub 2012 Jul 17.


alpha-Helical nascent polypeptide chains visualized within distinct regions of the ribosomal exit tunnel.

Bhushan S, Gartmann M, Halic M, Armache JP, Jarasch A, Mielke T, Berninghausen O, Wilson DN, Beckmann R.

Nat Struct Mol Biol. 2010 Mar;17(3):313-7. doi: 10.1038/nsmb.1756. Epub 2010 Feb 7.


Structured mRNAs regulate translation initiation by binding to the platform of the ribosome.

Marzi S, Myasnikov AG, Serganov A, Ehresmann C, Romby P, Yusupov M, Klaholz BP.

Cell. 2007 Sep 21;130(6):1019-31.


Biochemistry. Nascent proteins caught in the act.

Kampmann M, Blobel G.

Science. 2009 Dec 4;326(5958):1352-3. doi: 10.1126/science.1183690. No abstract available.


Trapping the ribosome to control gene expression.

Boehringer D, Ban N.

Cell. 2007 Sep 21;130(6):983-5.


Structural basis for translational stalling by human cytomegalovirus and fungal arginine attenuator peptide.

Bhushan S, Meyer H, Starosta AL, Becker T, Mielke T, Berninghausen O, Sattler M, Wilson DN, Beckmann R.

Mol Cell. 2010 Oct 8;40(1):138-46. doi: 10.1016/j.molcel.2010.09.009.


Biochemistry. Sense and sensitivity--controlling the ribosome.

Sachs MS, Geballe AP.

Science. 2002 Sep 13;297(5588):1820-1. No abstract available.


Crucial elements that maintain the interactions between the regulatory TnaC peptide and the ribosome exit tunnel responsible for Trp inhibition of ribosome function.

Martínez AK, Shirole NH, Murakami S, Benedik MJ, Sachs MS, Cruz-Vera LR.

Nucleic Acids Res. 2012 Mar;40(5):2247-57. doi: 10.1093/nar/gkr1052. Epub 2011 Nov 21.

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