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Results: 1 to 20 of 153

1.

Efficient serum clearance of botulinum neurotoxin achieved using a pool of small antitoxin binding agents.

Sepulveda J, Mukherjee J, Tzipori S, Simpson LL, Shoemaker CB.

Infect Immun. 2010 Feb;78(2):756-63. doi: 10.1128/IAI.01084-09. Epub 2009 Nov 16.

PMID:
19917718
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Mechanisms of enhanced neutralization of botulinum neurotoxin by monoclonal antibodies conjugated to antibodies specific for the erythrocyte complement receptor.

Sharma R, Zhao H, Al-Saleem FH, Ubaid AS, Puligedda RD, Segan AT, Lindorfer MA, Bermudez R, Elias M, Adekar SP, Simpson LL, Taylor RP, Dessain SK.

Mol Immunol. 2014 Feb;57(2):247-54. doi: 10.1016/j.molimm.2013.09.005. Epub 2013 Nov 1.

PMID:
24184879
[PubMed - indexed for MEDLINE]
Free Article
3.

Molecular characterization of murine humoral immune response to botulinum neurotoxin type A binding domain as assessed by using phage antibody libraries.

Amersdorfer P, Wong C, Chen S, Smith T, Deshpande S, Sheridan R, Finnern R, Marks JD.

Infect Immun. 1997 Sep;65(9):3743-52.

PMID:
9284147
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

A novel strategy for development of recombinant antitoxin therapeutics tested in a mouse botulism model.

Mukherjee J, Tremblay JM, Leysath CE, Ofori K, Baldwin K, Feng X, Bedenice D, Webb RP, Wright PM, Smith LA, Tzipori S, Shoemaker CB.

PLoS One. 2012;7(1):e29941. doi: 10.1371/journal.pone.0029941. Epub 2012 Jan 6.

PMID:
22238680
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Neutralizing antibodies of botulinum neurotoxin serotype A screened from a fully synthetic human antibody phage display library.

Yu R, Wang S, Yu YZ, Du WS, Yang F, Yu WY, Sun ZW.

J Biomol Screen. 2009 Sep;14(8):991-8. doi: 10.1177/1087057109343206. Epub 2009 Sep 2.

PMID:
19726786
[PubMed - indexed for MEDLINE]
6.

Expression of an anti-botulinum toxin A neutralizing single-chain Fv recombinant antibody in transgenic tobacco.

Almquist KC, McLean MD, Niu Y, Byrne G, Olea-Popelka FC, Murrant C, Barclay J, Hall JC.

Vaccine. 2006 Mar 15;24(12):2079-86. Epub 2005 Dec 1.

PMID:
16337316
[PubMed - indexed for MEDLINE]
7.

Mapping of the antibody-binding regions on botulinum neurotoxin H-chain domain 855-1296 with antitoxin antibodies from three host species.

Atassi MZ, Dolimbek BZ, Hayakari M, Middlebrook JL, Whitney B, Oshima M.

J Protein Chem. 1996 Oct;15(7):691-700.

PMID:
8968960
[PubMed - indexed for MEDLINE]
8.

Epitope characterization and variable region sequence of f1-40, a high-affinity monoclonal antibody to botulinum neurotoxin type a (Hall strain).

Scotcher MC, McGarvey JA, Johnson EA, Stanker LH.

PLoS One. 2009;4(3):e4924. doi: 10.1371/journal.pone.0004924. Epub 2009 Mar 17. Erratum in: PLoS One. 2009;4(10). doi: 10.1371/annotation/6359a6c2-90f8-4f7e-ad86-5bac5d62a7fe. PLoS One. 2009;4(11). doi: 10.1371/annotation/6359a6c2-90f8-4f7e-ad86-5bac5d62a7fe. PLoS One. 2009;4(10). doi: 10.1371/annotation/8d83a0a4-4dd0-4c57-ad94-304130f565e6. PLoS One. 2009;4(10). doi: 10.1371/annotation/47f9bc3f-7c79-453c-85e3-588bc3056951.

PMID:
19290051
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Development and partial characterization of high-affinity monoclonal antibodies for botulinum toxin type A and their use in analysis of milk by sandwich ELISA.

Stanker LH, Merrill P, Scotcher MC, Cheng LW.

J Immunol Methods. 2008 Jul 20;336(1):1-8. doi: 10.1016/j.jim.2008.03.003. Epub 2008 Apr 9.

PMID:
18452945
[PubMed - indexed for MEDLINE]
10.

Submolecular recognition profiles in two mouse strains of non-protective and protective antibodies against botulinum neurotoxin A.

Atassi MZ, Dolimbek GS, Deitiker PR, Aoki KR, Dolimbek BZ.

Mol Immunol. 2005 Aug;42(12):1509-20. Epub 2005 Mar 21.

PMID:
15950744
[PubMed - indexed for MEDLINE]
11.

Uptake of botulinum neurotoxin into cultured neurons.

Keller JE, Cai F, Neale EA.

Biochemistry. 2004 Jan 20;43(2):526-32.

PMID:
14717608
[PubMed - indexed for MEDLINE]
12.

Mapping of the regions on the heavy chain of botulinum neurotoxin A (BoNT/A) recognized by antibodies of cervical dystonia patients with immunoresistance to BoNT/A.

Dolimbek BZ, Aoki KR, Steward LE, Jankovic J, Atassi MZ.

Mol Immunol. 2007 Feb;44(5):1029-41. Epub 2006 May 2.

PMID:
16647121
[PubMed - indexed for MEDLINE]
13.

Neutralizing human monoclonal antibodies binding multiple serotypes of botulinum neurotoxin.

Garcia-Rodriguez C, Geren IN, Lou J, Conrad F, Forsyth C, Wen W, Chakraborti S, Zao H, Manzanarez G, Smith TJ, Brown J, Tepp WH, Liu N, Wijesuriya S, Tomic MT, Johnson EA, Smith LA, Marks JD.

Protein Eng Des Sel. 2011 Mar;24(3):321-31. doi: 10.1093/protein/gzq111. Epub 2010 Dec 13.

PMID:
21149386
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Enhanced neutralization potency of botulinum neurotoxin antibodies using a red blood cell-targeting fusion protein.

Adekar SP, Segan AT, Chen C, Bermudez R, Elias MD, Selling BH, Kapadnis BP, Simpson LL, Simon PM, Dessain SK.

PLoS One. 2011 Mar 2;6(3):e17491. doi: 10.1371/journal.pone.0017491.

PMID:
21399689
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Divalent forms of CC49 single-chain antibody constructs in Pichia pastoris: expression, purification, and characterization.

Goel A, Beresford GW, Colcher D, Pavlinkova G, Booth BJ, Baranowska-Kortylewicz J, Batra SK.

J Biochem. 2000 May;127(5):829-36.

PMID:
10788792
[PubMed - indexed for MEDLINE]
Free Article
16.
17.

Anomalous enhancement of botulinum toxin type A neurotoxicity in the presence of antitoxin.

Sheridan RE, Deshpande SS, Amersdorfer P, Marks JD, Smith T.

Toxicon. 2001 May;39(5):651-7.

PMID:
11072043
[PubMed - indexed for MEDLINE]
18.

Development and evaluation of candidate vaccine and antitoxin against botulinum neurotoxin serotype F.

Yu YZ, Zhang SM, Ma Y, Zhu HQ, Wang WB, Du Y, Zhou XW, Wang RL, Wang S, Yu WY, Huang PT, Sun ZW.

Clin Immunol. 2010 Nov;137(2):271-80. doi: 10.1016/j.clim.2010.07.005. Epub 2010 Aug 8.

PMID:
20696619
[PubMed - indexed for MEDLINE]
19.

Characterization of botulinum neurotoxin type A neutralizing monoclonal antibodies and influence of their half-lives on therapeutic activity.

Mazuet C, Dano J, Popoff MR, Créminon C, Volland H.

PLoS One. 2010 Aug 26;5(8):e12416. doi: 10.1371/journal.pone.0012416.

PMID:
20865035
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Characterization of the monoclonal antibody response to botulinum neurotoxin type A in the complexed and uncomplexed forms.

Zhao H, Nakamura K, Kohda T, Mukamoto M, Kozaki S.

Jpn J Infect Dis. 2012;65(2):138-45.

PMID:
22446121
[PubMed - indexed for MEDLINE]
Free Article
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