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Results: 1 to 20 of 120

1.

Fluorescence resonance energy transfer analysis of merlin conformational changes.

Hennigan RF, Foster LA, Chaiken MF, Mani T, Gomes MM, Herr AB, Ip W.

Mol Cell Biol. 2010 Jan;30(1):54-67. doi: 10.1128/MCB.00248-09. Epub .

PMID:
19884346
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Tumor-suppression functions of merlin are independent of its role as an organizer of the actin cytoskeleton in Schwann cells.

Lallemand D, Saint-Amaux AL, Giovannini M.

J Cell Sci. 2009 Nov 15;122(Pt 22):4141-9. doi: 10.1242/jcs.045914.

PMID:
19910496
[PubMed - indexed for MEDLINE]
Free Article
3.

Structural basis for neurofibromatosis type 2. Crystal structure of the merlin FERM domain.

Shimizu T, Seto A, Maita N, Hamada K, Tsukita S, Tsukita S, Hakoshima T.

J Biol Chem. 2002 Mar 22;277(12):10332-6. Epub 2001 Dec 27.

PMID:
11756419
[PubMed - indexed for MEDLINE]
Free Article
4.

Interaction between two isoforms of the NF2 tumor suppressor protein, merlin, and between merlin and ezrin, suggests modulation of ERM proteins by merlin.

Meng JJ, Lowrie DJ, Sun H, Dorsey E, Pelton PD, Bashour AM, Groden J, Ratner N, Ip W.

J Neurosci Res. 2000 Nov 15;62(4):491-502.

PMID:
11070492
[PubMed - indexed for MEDLINE]
5.

Unfurling of the band 4.1, ezrin, radixin, moesin (FERM) domain of the merlin tumor suppressor.

Yogesha SD, Sharff AJ, Giovannini M, Bricogne G, Izard T.

Protein Sci. 2011 Dec;20(12):2113-20. doi: 10.1002/pro.751. Epub 2011 Nov 9.

PMID:
22012890
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Insights into a single rod-like helix in activated radixin required for membrane-cytoskeletal cross-linking.

Hoeflich KP, Tsukita S, Hicks L, Kay CM, Tsukita S, Ikura M.

Biochemistry. 2003 Oct 14;42(40):11634-41.

PMID:
14529273
[PubMed - indexed for MEDLINE]
7.

Protein kinase A-mediated phosphorylation of the NF2 tumor suppressor protein merlin at serine 10 affects the actin cytoskeleton.

Laulajainen M, Muranen T, Carpén O, Grönholm M.

Oncogene. 2008 May 22;27(23):3233-43. Epub 2007 Dec 10.

PMID:
18071304
[PubMed - indexed for MEDLINE]
8.
9.

The tumor suppressor merlin interacts with microtubules and modulates Schwann cell microtubule cytoskeleton.

Muranen T, Grönholm M, Lampin A, Lallemand D, Zhao F, Giovannini M, Carpén O.

Hum Mol Genet. 2007 Jul 15;16(14):1742-51. Epub 2007 Jun 12.

PMID:
17566081
[PubMed - indexed for MEDLINE]
Free Article
10.

Three dimensional structure of the closed conformation (active) of human merlin reveals masking of actin binding site in the FERM domain.

Sivakumar KC, Thomas B, Karunagaran D.

Int J Bioinform Res Appl. 2009;5(5):516-24.

PMID:
19778867
[PubMed - indexed for MEDLINE]
11.

Evolution and origin of merlin, the product of the Neurofibromatosis type 2 (NF2) tumor-suppressor gene.

Golovnina K, Blinov A, Akhmametyeva EM, Omelyanchuk LV, Chang LS.

BMC Evol Biol. 2005 Dec 2;5:69.

PMID:
16324214
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Molecular conformation of the full-length tumor suppressor NF2/Merlin--a small-angle neutron scattering study.

Ali Khajeh J, Ju JH, Atchiba M, Allaire M, Stanley C, Heller WT, Callaway DJ, Bu Z.

J Mol Biol. 2014 Jul 29;426(15):2755-68. doi: 10.1016/j.jmb.2014.05.011. Epub 2014 May 29.

PMID:
24882693
[PubMed - indexed for MEDLINE]
13.

The structure of the FERM domain of merlin, the neurofibromatosis type 2 gene product.

Kang BS, Cooper DR, Devedjiev Y, Derewenda U, Derewenda ZS.

Acta Crystallogr D Biol Crystallogr. 2002 Mar;58(Pt 3):381-91. Epub 2002 Feb 21.

PMID:
11856822
[PubMed - indexed for MEDLINE]
14.

Homotypic and heterotypic interaction of the neurofibromatosis 2 tumor suppressor protein merlin and the ERM protein ezrin.

Grönholm M, Sainio M, Zhao F, Heiska L, Vaheri A, Carpén O.

J Cell Sci. 1999 Mar;112 ( Pt 6):895-904.

PMID:
10036239
[PubMed - indexed for MEDLINE]
Free Article
15.

Interdomain interaction of merlin isoforms and its influence on intermolecular binding to NHE-RF.

Gonzalez-Agosti C, Wiederhold T, Herndon ME, Gusella J, Ramesh V.

J Biol Chem. 1999 Nov 26;274(48):34438-42.

PMID:
10567424
[PubMed - indexed for MEDLINE]
Free Article
16.

FERM domain phosphoinositide binding targets merlin to the membrane and is essential for its growth-suppressive function.

Mani T, Hennigan RF, Foster LA, Conrady DG, Herr AB, Ip W.

Mol Cell Biol. 2011 May;31(10):1983-96. doi: 10.1128/MCB.00609-10. Epub 2011 Mar 14.

PMID:
21402777
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The NF2 tumor suppressor Merlin and the ERM proteins interact with N-WASP and regulate its actin polymerization function.

Manchanda N, Lyubimova A, Ho HY, James MF, Gusella JF, Ramesh N, Snapper SB, Ramesh V.

J Biol Chem. 2005 Apr 1;280(13):12517-22. Epub 2005 Feb 7.

PMID:
15699051
[PubMed - indexed for MEDLINE]
Free Article
18.

Effect of merlin phosphorylation on neurofibromatosis 2 (NF2) gene function.

Surace EI, Haipek CA, Gutmann DH.

Oncogene. 2004 Jan 15;23(2):580-7.

PMID:
14724586
[PubMed - indexed for MEDLINE]
19.

Functional analysis of the neurofibromatosis type 2 protein by means of disease-causing point mutations.

Stokowski RP, Cox DR.

Am J Hum Genet. 2000 Mar;66(3):873-91.

PMID:
10712203
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling.

Shaw RJ, Paez JG, Curto M, Yaktine A, Pruitt WM, Saotome I, O'Bryan JP, Gupta V, Ratner N, Der CJ, Jacks T, McClatchey AI.

Dev Cell. 2001 Jul;1(1):63-72.

PMID:
11703924
[PubMed - indexed for MEDLINE]
Free Article

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