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Results: 1 to 20 of 97

1.

Inhibition of HDAC9 increases T regulatory cell function and prevents colitis in mice.

de Zoeten EF, Wang L, Sai H, Dillmann WH, Hancock WW.

Gastroenterology. 2010 Feb;138(2):583-94. doi: 10.1053/j.gastro.2009.10.037. Epub 2009 Oct 29.

PMID:
19879272
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Histone deacetylases 6 and 9 and sirtuin-1 control Foxp3+ regulatory T cell function through shared and isoform-specific mechanisms.

Beier UH, Wang L, Han R, Akimova T, Liu Y, Hancock WW.

Sci Signal. 2012 Jun 19;5(229):ra45. doi: 10.1126/scisignal.2002873.

PMID:
22715468
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Histone deacetylase 6 and heat shock protein 90 control the functions of Foxp3(+) T-regulatory cells.

de Zoeten EF, Wang L, Butler K, Beier UH, Akimova T, Sai H, Bradner JE, Mazitschek R, Kozikowski AP, Matthias P, Hancock WW.

Mol Cell Biol. 2011 May;31(10):2066-78. doi: 10.1128/MCB.05155-11. Epub 2011 Mar 28.

PMID:
21444725
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression.

Fantini MC, Rizzo A, Fina D, Caruso R, Sarra M, Stolfi C, Becker C, Macdonald TT, Pallone F, Neurath MF, Monteleone G.

Gastroenterology. 2009 Apr;136(4):1308-16, e1-3. doi: 10.1053/j.gastro.2008.12.053. Epub 2008 Dec 27.

PMID:
19192480
[PubMed - indexed for MEDLINE]
5.

Type I interferons maintain Foxp3 expression and T-regulatory cell functions under inflammatory conditions in mice.

Lee SE, Li X, Kim JC, Lee J, González-Navajas JM, Hong SH, Park IK, Rhee JH, Raz E.

Gastroenterology. 2012 Jul;143(1):145-54. doi: 10.1053/j.gastro.2012.03.042. Epub 2012 Apr 1. Erratum in: Gastroenterology. 2013 May;144(5):1157.

PMID:
22475534
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Deacetylase inhibition promotes the generation and function of regulatory T cells.

Tao R, de Zoeten EF, Ozkaynak E, Chen C, Wang L, Porrett PM, Li B, Turka LA, Olson EN, Greene MI, Wells AD, Hancock WW.

Nat Med. 2007 Nov;13(11):1299-307. Epub 2007 Oct 7.

PMID:
17922010
[PubMed - indexed for MEDLINE]
7.

Transient local depletion of Foxp3+ regulatory T cells during recovery from colitis via Fas/Fas ligand-induced death.

Reardon C, Wang A, McKay DM.

J Immunol. 2008 Jun 15;180(12):8316-26.

PMID:
18523298
[PubMed - indexed for MEDLINE]
Free Article
8.

Deacetylase inhibition increases regulatory T cell function and decreases incidence and severity of collagen-induced arthritis.

Saouaf SJ, Li B, Zhang G, Shen Y, Furuuchi N, Hancock WW, Greene MI.

Exp Mol Pathol. 2009 Oct;87(2):99-104. doi: 10.1016/j.yexmp.2009.06.003. Epub 2009 Jul 3.

PMID:
19577564
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Redirection of regulatory T cells with predetermined specificity for the treatment of experimental colitis in mice.

Elinav E, Waks T, Eshhar Z.

Gastroenterology. 2008 Jun;134(7):2014-24. doi: 10.1053/j.gastro.2008.02.060. Epub 2008 Mar 4.

PMID:
18424268
[PubMed - indexed for MEDLINE]
10.

Foxp3 processing by proprotein convertases and control of regulatory T cell function.

de Zoeten EF, Lee I, Wang L, Chen C, Ge G, Wells AD, Hancock WW, Ozkaynak E.

J Biol Chem. 2009 Feb 27;284(9):5709-16. doi: 10.1074/jbc.M807322200. Epub 2008 Dec 24.

PMID:
19117830
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Histone/protein deacetylase inhibitors increase suppressive functions of human FOXP3+ Tregs.

Akimova T, Ge G, Golovina T, Mikheeva T, Wang L, Riley JL, Hancock WW.

Clin Immunol. 2010 Sep;136(3):348-63. doi: 10.1016/j.clim.2010.04.018. Epub 2010 May 15.

PMID:
20478744
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Class I histone deacetylase inhibitor entinostat suppresses regulatory T cells and enhances immunotherapies in renal and prostate cancer models.

Shen L, Ciesielski M, Ramakrishnan S, Miles KM, Ellis L, Sotomayor P, Shrikant P, Fenstermaker R, Pili R.

PLoS One. 2012;7(1):e30815. doi: 10.1371/journal.pone.0030815. Epub 2012 Jan 27.

PMID:
22303460
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Histone deacetylase inhibitors and transplantation.

Tao R, de Zoeten EF, Ozkaynak E, Wang L, Li B, Greene MI, Wells AD, Hancock WW.

Curr Opin Immunol. 2007 Oct;19(5):589-95. Epub 2007 Aug 24. Review.

PMID:
17719760
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The influence of excessive IL-6 production in vivo on the development and function of Foxp3+ regulatory T cells.

Fujimoto M, Nakano M, Terabe F, Kawahata H, Ohkawara T, Han Y, Ripley B, Serada S, Nishikawa T, Kimura A, Nomura S, Kishimoto T, Naka T.

J Immunol. 2011 Jan 1;186(1):32-40. doi: 10.4049/jimmunol.0903314. Epub 2010 Nov 24.

PMID:
21106853
[PubMed - indexed for MEDLINE]
Free Article
15.

The effects of Foxp3-expressing regulatory T cells expanded with CD28 superagonist antibody in DSS-induced mice colitis.

Chen J, Xie L, Toyama S, Hünig T, Takahara S, Li XK, Zhong L.

Int Immunopharmacol. 2011 May;11(5):610-7. doi: 10.1016/j.intimp.2010.11.034. Epub 2010 Dec 14.

PMID:
21163250
[PubMed - indexed for MEDLINE]
16.

Histone deacetylase 9 deficiency protects against effector T cell-mediated systemic autoimmunity.

Yan K, Cao Q, Reilly CM, Young NL, Garcia BA, Mishra N.

J Biol Chem. 2011 Aug 19;286(33):28833-43. doi: 10.1074/jbc.M111.233932. Epub 2011 Jun 27.

PMID:
21708950
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Nonfunctional regulatory T cells and defective control of Th2 cytokine production in natural scurfy mutant mice.

Lahl K, Mayer CT, Bopp T, Huehn J, Loddenkemper C, Eberl G, Wirnsberger G, Dornmair K, Geffers R, Schmitt E, Buer J, Sparwasser T.

J Immunol. 2009 Nov 1;183(9):5662-72. doi: 10.4049/jimmunol.0803762. Epub 2009 Oct 7.

PMID:
19812199
[PubMed - indexed for MEDLINE]
Free Article
18.

Foxp3+ T-regulatory cells require DNA methyltransferase 1 expression to prevent development of lethal autoimmunity.

Wang L, Liu Y, Beier UH, Han R, Bhatti TR, Akimova T, Hancock WW.

Blood. 2013 May 2;121(18):3631-9. doi: 10.1182/blood-2012-08-451765. Epub 2013 Feb 26.

PMID:
23444399
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

CD8+CD122+ regulatory T cells (Tregs) and CD4+ Tregs cooperatively prevent and cure CD4+ cell-induced colitis.

Endharti AT, Okuno Y, Shi Z, Misawa N, Toyokuni S, Ito M, Isobe K, Suzuki H.

J Immunol. 2011 Jan 1;186(1):41-52. doi: 10.4049/jimmunol.1000800. Epub 2010 Nov 22.

PMID:
21098236
[PubMed - indexed for MEDLINE]
Free Article
20.

Specific control of pancreatic endocrine β- and δ-cell mass by class IIa histone deacetylases HDAC4, HDAC5, and HDAC9.

Lenoir O, Flosseau K, Ma FX, Blondeau B, Mai A, Bassel-Duby R, Ravassard P, Olson EN, Haumaitre C, Scharfmann R.

Diabetes. 2011 Nov;60(11):2861-71. doi: 10.2337/db11-0440. Epub 2011 Sep 27.

PMID:
21953612
[PubMed - indexed for MEDLINE]
Free PMC Article

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