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Items: 1 to 20 of 160

1.

Crystal structure of albaflavenone monooxygenase containing a moonlighting terpene synthase active site.

Zhao B, Lei L, Vassylyev DG, Lin X, Cane DE, Kelly SL, Yuan H, Lamb DC, Waterman MR.

J Biol Chem. 2009 Dec 25;284(52):36711-9. doi: 10.1074/jbc.M109.064683. Epub 2009 Oct 26.

2.

Investigating conservation of the albaflavenone biosynthetic pathway and CYP170 bifunctionality in streptomycetes.

Moody SC, Zhao B, Lei L, Nelson DR, Mullins JG, Waterman MR, Kelly SL, Lamb DC.

FEBS J. 2012 May;279(9):1640-9. doi: 10.1111/j.1742-4658.2011.08447.x. Epub 2012 Jan 27.

3.

Biosynthesis of the sesquiterpene antibiotic albaflavenone in Streptomyces coelicolor A3(2).

Zhao B, Lin X, Lei L, Lamb DC, Kelly SL, Waterman MR, Cane DE.

J Biol Chem. 2008 Mar 28;283(13):8183-9. doi: 10.1074/jbc.M710421200. Epub 2008 Jan 30.

4.

Characterization of a silent sesquiterpenoid biosynthetic pathway in Streptomyces avermitilis controlling epi-isozizaene albaflavenone biosynthesis and isolation of a new oxidized epi-isozizaene metabolite.

Takamatsu S, Lin X, Nara A, Komatsu M, Cane DE, Ikeda H.

Microb Biotechnol. 2011 Mar;4(2):184-91. doi: 10.1111/j.1751-7915.2010.00209.x. Epub 2010 Sep 27.

5.

Moonlighting cytochrome P450 monooxygenases.

Zhao B, Waterman MR.

IUBMB Life. 2011 Jul;63(7):473-7. doi: 10.1002/iub.501.

6.

X-ray crystal structure of aristolochene synthase from Aspergillus terreus and evolution of templates for the cyclization of farnesyl diphosphate.

Shishova EY, Di Costanzo L, Cane DE, Christianson DW.

Biochemistry. 2007 Feb 20;46(7):1941-51. Epub 2007 Jan 30.

7.

Structural analysis of cytochrome P450 105N1 involved in the biosynthesis of the zincophore, coelibactin.

Zhao B, Moody SC, Hider RC, Lei L, Kelly SL, Waterman MR, Lamb DC.

Int J Mol Sci. 2012;13(7):8500-13. doi: 10.3390/ijms13078500. Epub 2012 Jun 1.

8.
9.

Identification of sesquiterpene synthases from Nostoc punctiforme PCC 73102 and Nostoc sp. strain PCC 7120.

Agger SA, Lopez-Gallego F, Hoye TR, Schmidt-Dannert C.

J Bacteriol. 2008 Sep;190(18):6084-96. doi: 10.1128/JB.00759-08. Epub 2008 Jul 25.

10.

The Structure of Mycobacterium tuberculosis CYP125: molecular basis for cholesterol binding in a P450 needed for host infection.

McLean KJ, Lafite P, Levy C, Cheesman MR, Mast N, Pikuleva IA, Leys D, Munro AW.

J Biol Chem. 2009 Dec 18;284(51):35524-33. doi: 10.1074/jbc.M109.032706. Epub .

11.
12.

Structure of epi-isozizaene synthase from Streptomyces coelicolor A3(2), a platform for new terpenoid cyclization templates.

Aaron JA, Lin X, Cane DE, Christianson DW.

Biochemistry. 2010 Mar 2;49(8):1787-97. doi: 10.1021/bi902088z.

13.

Defining the potassium binding region in an apple terpene synthase.

Green S, Squire CJ, Nieuwenhuizen NJ, Baker EN, Laing W.

J Biol Chem. 2009 Mar 27;284(13):8661-9. doi: 10.1074/jbc.M807140200. Epub 2009 Jan 29.

15.

Structural basis for cyclic terpene biosynthesis by tobacco 5-epi-aristolochene synthase.

Starks CM, Back K, Chappell J, Noel JP.

Science. 1997 Sep 19;277(5333):1815-20.

16.

Crystal structure of cytochrome P450 CYP105N1 from Streptomyces coelicolor, an oxidase in the coelibactin siderophore biosynthetic pathway.

Lim YR, Hong MK, Kim JK, Doan TT, Kim DH, Yun CH, Chun YJ, Kang LW, Kim D.

Arch Biochem Biophys. 2012 Dec 15;528(2):111-7. doi: 10.1016/j.abb.2012.09.001. Epub 2012 Sep 18.

PMID:
23000034
17.

Different binding modes of two flaviolin substrate molecules in cytochrome P450 158A1 (CYP158A1) compared to CYP158A2.

Zhao B, Lamb DC, Lei L, Kelly SL, Yuan H, Hachey DL, Waterman MR.

Biochemistry. 2007 Jul 31;46(30):8725-33. Epub 2007 Jul 6.

PMID:
17614370
18.

Inhibition of a multiproduct terpene synthase from Medicago truncatula by 3-bromoprenyl diphosphates.

Vattekkatte A, Gatto N, Schulze E, Brandt W, Boland W.

Org Biomol Chem. 2015 Apr 28;13(16):4776-84. doi: 10.1039/c5ob00506j.

PMID:
25807032
19.

Reprogramming the chemodiversity of terpenoid cyclization by remolding the active site contour of epi-isozizaene synthase.

Li R, Chou WK, Himmelberger JA, Litwin KM, Harris GG, Cane DE, Christianson DW.

Biochemistry. 2014 Feb 25;53(7):1155-68. doi: 10.1021/bi401643u. Epub 2014 Feb 11.

20.
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