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Related Citations for PubMed (Select 19843788)


Isoflurane-induced changes in righting response and breathing are modulated by RGS proteins.

Icaza EE, Huang X, Fu Y, Neubig RR, Baghdoyan HA, Lydic R.

Anesth Analg. 2009 Nov;109(5):1500-5. doi: 10.1213/ANE.0b013e3181ba7815.


Gα(i2)-mediated protection from ischaemic injury is modulated by endogenous RGS proteins in the mouse heart.

Waterson RE, Thompson CG, Mabe NW, Kaur K, Talbot JN, Neubig RR, Rorabaugh BR.

Cardiovasc Res. 2011 Jul 1;91(1):45-52. doi: 10.1093/cvr/cvr054. Epub 2011 Feb 23.


Toll-like receptor-induced inflammatory cytokines are suppressed by gain of function or overexpression of Gα(i2) protein.

Li P, Neubig RR, Zingarelli B, Borg K, Halushka PV, Cook JA, Fan H.

Inflammation. 2012 Oct;35(5):1611-7. doi: 10.1007/s10753-012-9476-z.


RGS inhibition at G(alpha)i2 selectively potentiates 5-HT1A-mediated antidepressant effects.

Talbot JN, Jutkiewicz EM, Graves SM, Clemans CF, Nicol MR, Mortensen RM, Huang X, Neubig RR, Traynor JR.

Proc Natl Acad Sci U S A. 2010 Jun 15;107(24):11086-91. doi: 10.1073/pnas.1000003107. Epub 2010 Jun 2.


Resistance to diet-induced obesity and improved insulin sensitivity in mice with a regulator of G protein signaling-insensitive G184S Gnai2 allele.

Huang X, Charbeneau RA, Fu Y, Kaur K, Gerin I, MacDougald OA, Neubig RR.

Diabetes. 2008 Jan;57(1):77-85. Epub 2007 Oct 10.


Pleiotropic phenotype of a genomic knock-in of an RGS-insensitive G184S Gnai2 allele.

Huang X, Fu Y, Charbeneau RA, Saunders TL, Taylor DK, Hankenson KD, Russell MW, D'Alecy LG, Neubig RR.

Mol Cell Biol. 2006 Sep;26(18):6870-9.


Endogenous RGS proteins modulate SA and AV nodal functions in isolated heart: implications for sick sinus syndrome and AV block.

Fu Y, Huang X, Piao L, Lopatin AN, Neubig RR.

Am J Physiol Heart Circ Physiol. 2007 May;292(5):H2532-9. Epub 2007 Feb 2.


RGS/Gi2alpha interactions modulate platelet accumulation and thrombus formation at sites of vascular injury.

Signarvic RS, Cierniewska A, Stalker TJ, Fong KP, Chatterjee MS, Hess PR, Ma P, Diamond SL, Neubig RR, Brass LF.

Blood. 2010 Dec 23;116(26):6092-100. doi: 10.1182/blood-2010-05-283846. Epub 2010 Sep 17.


The loss of RGS protein-Gα(i2) interactions results in markedly impaired mouse neutrophil trafficking to inflammatory sites.

Cho H, Kamenyeva O, Yung S, Gao JL, Hwang IY, Park C, Murphy PM, Neubig RR, Kehrl JH.

Mol Cell Biol. 2012 Nov;32(22):4561-71. doi: 10.1128/MCB.00651-12. Epub 2012 Sep 10.


Conditional disruption of interactions between Gαi2 and regulator of G protein signaling (RGS) proteins protects the heart from ischemic injury.

Parra S, Huang X, Charbeneau RA, Wade SM, Kaur K, Rorabaugh BR, Neubig RR.

BMC Pharmacol Toxicol. 2014 Jun 5;15:29. doi: 10.1186/2050-6511-15-29.


Regulator of G protein signaling protein suppression of Galphao protein-mediated alpha2A adrenergic receptor inhibition of mouse hippocampal CA3 epileptiform activity.

Goldenstein BL, Nelson BW, Xu K, Luger EJ, Pribula JA, Wald JM, O'Shea LA, Weinshenker D, Charbeneau RA, Huang X, Neubig RR, Doze VA.

Mol Pharmacol. 2009 May;75(5):1222-30. doi: 10.1124/mol.108.054296. Epub 2009 Feb 18.


Gαi2 signaling: friend or foe in cardiac injury and heart failure?

Kaur K, Parra S, Chen R, Charbeneau RA, Wade SM, Jay PY, Neubig RR.

Naunyn Schmiedebergs Arch Pharmacol. 2012 May;385(5):443-53. doi: 10.1007/s00210-011-0705-z. Epub 2012 Mar 14.


Gαi2- and Gαi3-specific regulation of voltage-dependent L-type calcium channels in cardiomyocytes.

Dizayee S, Kaestner S, Kuck F, Hein P, Klein C, Piekorz RP, Meszaros J, Matthes J, Bjrnbaumer L, Nürnberg B, Herzig S.

PLoS One. 2011;6(9):e24979. doi: 10.1371/journal.pone.0024979. Epub 2011 Sep 26. Erratum in: PLoS One. 2013;8(8). doi:10.1371/annotation/7be097c0-9075-41ae-91e9-d2209de952cc. Bjrnbaumer, Lutz [added].


Differential control of opioid antinociception to thermal stimuli in a knock-in mouse expressing regulator of G-protein signaling-insensitive Gαo protein.

Lamberts JT, Smith CE, Li MH, Ingram SL, Neubig RR, Traynor JR.

J Neurosci. 2013 Mar 6;33(10):4369-77. doi: 10.1523/JNEUROSCI.5470-12.2013.


Gα subunit coordinates with ephrin-B to balance self-renewal and differentiation in neural progenitor cells.

Murai K, Qiu R, Zhang H, Wang J, Wu C, Neubig RR, Lu Q.

Stem Cells. 2010 Sep;28(9):1581-9. doi: 10.1002/stem.474.


Endogenous regulators of G protein signaling differentially modulate full and partial mu-opioid agonists at adenylyl cyclase as predicted by a collision coupling model.

Clark MJ, Linderman JJ, Traynor JR.

Mol Pharmacol. 2008 May;73(5):1538-48. doi: 10.1124/mol.107.043547. Epub 2008 Feb 19.


RGS-insensitive G-protein mutations to study the role of endogenous RGS proteins.

Fu Y, Zhong H, Nanamori M, Mortensen RM, Huang X, Lan K, Neubig RR.

Methods Enzymol. 2004;389:229-43. Review.


Endogenous RGS proteins and Galpha subtypes differentially control muscarinic and adenosine-mediated chronotropic effects.

Fu Y, Huang X, Zhong H, Mortensen RM, D'Alecy LG, Neubig RR.

Circ Res. 2006 Mar 17;98(5):659-66. Epub 2006 Feb 2.


Endogenous RGS proteins attenuate Galpha(i)-mediated lysophosphatidic acid signaling pathways in ovarian cancer cells.

Hurst JH, Henkel PA, Brown AL, Hooks SB.

Cell Signal. 2008 Feb;20(2):381-9. Epub 2007 Nov 7.

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