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Results: 1 to 20 of 143

1.

Role of beta3-adrenoceptors for intrahepatic resistance and portal hypertension in liver cirrhosis.

Trebicka J, Hennenberg M, Schulze Pröbsting A, Laleman W, Klein S, Granzow M, Nevens F, Zaagsma J, Heller J, Sauerbruch T.

Hepatology. 2009 Dec;50(6):1924-35. doi: 10.1002/hep.23222.

PMID:
19842096
[PubMed - indexed for MEDLINE]
2.

Atorvastatin lowers portal pressure in cirrhotic rats by inhibition of RhoA/Rho-kinase and activation of endothelial nitric oxide synthase.

Trebicka J, Hennenberg M, Laleman W, Shelest N, Biecker E, Schepke M, Nevens F, Sauerbruch T, Heller J.

Hepatology. 2007 Jul;46(1):242-53.

PMID:
17596891
[PubMed - indexed for MEDLINE]
3.

Hemodynamic effects of urotensin II and its specific receptor antagonist palosuran in cirrhotic rats.

Trebicka J, Leifeld L, Hennenberg M, Biecker E, Eckhardt A, Fischer N, Pröbsting AS, Clemens C, Lammert F, Sauerbruch T, Heller J.

Hepatology. 2008 Apr;47(4):1264-76. doi: 10.1002/hep.22170.

PMID:
18318439
[PubMed - indexed for MEDLINE]
4.

Spironolactone lowers portal hypertension by inhibiting liver fibrosis, ROCK-2 activity and activating NO/PKG pathway in the bile-duct-ligated rat.

Luo W, Meng Y, Ji HL, Pan CQ, Huang S, Yu CH, Xiao LM, Cui K, Ni SY, Zhang ZS, Li X.

PLoS One. 2012;7(3):e34230. doi: 10.1371/journal.pone.0034230. Epub 2012 Mar 30.

PMID:
22479572
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Intrahepatic upregulation of RhoA and Rho-kinase signalling contributes to increased hepatic vascular resistance in rats with secondary biliary cirrhosis.

Zhou Q, Hennenberg M, Trebicka J, Jochem K, Leifeld L, Biecker E, Sauerbruch T, Heller J.

Gut. 2006 Sep;55(9):1296-305. Epub 2006 Feb 21.

PMID:
16492715
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Portal hypertension and liver cirrhosis in rats: effect of the β3-adrenoceptor agonist SR58611A.

Vasina V, Giannone F, Domenicali M, Latorre R, Berzigotti A, Caraceni P, Zoli M, De Ponti F, Bernardi M.

Br J Pharmacol. 2012 Nov;167(5):1137-47. doi: 10.1111/j.1476-5381.2012.02074.x.

PMID:
22708587
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Activation of the MAS receptor by angiotensin-(1-7) in the renin-angiotensin system mediates mesenteric vasodilatation in cirrhosis.

Grace JA, Klein S, Herath CB, Granzow M, Schierwagen R, Masing N, Walther T, Sauerbruch T, Burrell LM, Angus PW, Trebicka J.

Gastroenterology. 2013 Oct;145(4):874-884.e5. doi: 10.1053/j.gastro.2013.06.036. Epub 2013 Jun 22.

PMID:
23796456
[PubMed - indexed for MEDLINE]
8.

Treatment of bile duct-ligated rats with the nitric oxide synthase transcription enhancer AVE 9488 ameliorates portal hypertension.

Biecker E, Trebicka J, Kang A, Hennenberg M, Sauerbruch T, Heller J.

Liver Int. 2008 Mar;28(3):331-8. doi: 10.1111/j.1478-3231.2008.01664.x.

PMID:
18290775
[PubMed - indexed for MEDLINE]
9.

HSC-specific inhibition of Rho-kinase reduces portal pressure in cirrhotic rats without major systemic effects.

Klein S, Van Beuge MM, Granzow M, Beljaars L, Schierwagen R, Kilic S, Heidari I, Huss S, Sauerbruch T, Poelstra K, Trebicka J.

J Hepatol. 2012 Dec;57(6):1220-7. doi: 10.1016/j.jhep.2012.07.033. Epub 2012 Aug 6.

PMID:
22878469
[PubMed - indexed for MEDLINE]
10.

Terutroban, a TP-receptor antagonist, reduces portal pressure in cirrhotic rats.

Rosado E, Rodríguez-Vilarrupla A, Gracia-Sancho J, Tripathi D, García-Calderó H, Bosch J, García-Pagán JC.

Hepatology. 2013 Oct;58(4):1424-35. doi: 10.1002/hep.26520. Epub 2013 Aug 7.

PMID:
23703868
[PubMed - indexed for MEDLINE]
11.

Beneficial effects of sorafenib on splanchnic, intrahepatic, and portocollateral circulations in portal hypertensive and cirrhotic rats.

Mejias M, Garcia-Pras E, Tiani C, Miquel R, Bosch J, Fernandez M.

Hepatology. 2009 Apr;49(4):1245-56. doi: 10.1002/hep.22758.

PMID:
19137587
[PubMed - indexed for MEDLINE]
12.

Relaxin modulates human and rat hepatic myofibroblast function and ameliorates portal hypertension in vivo.

Fallowfield JA, Hayden AL, Snowdon VK, Aucott RL, Stutchfield BM, Mole DJ, Pellicoro A, Gordon-Walker TT, Henke A, Schrader J, Trivedi PJ, Princivalle M, Forbes SJ, Collins JE, Iredale JP.

Hepatology. 2014 Apr;59(4):1492-504. doi: 10.1002/hep.26627. Epub 2014 Mar 3.

PMID:
23873655
[PubMed - indexed for MEDLINE]
13.

Antagonism of sphingosine 1-phosphate receptor 2 causes a selective reduction of portal vein pressure in bile duct-ligated rodents.

Kageyama Y, Ikeda H, Watanabe N, Nagamine M, Kusumoto Y, Yashiro M, Satoh Y, Shimosawa T, Shinozaki K, Tomiya T, Inoue Y, Nishikawa T, Ohtomo N, Tanoue Y, Yokota H, Koyama T, Ishimaru K, Okamoto Y, Takuwa Y, Koike K, Yatomi Y.

Hepatology. 2012 Oct;56(4):1427-38. doi: 10.1002/hep.25780.

PMID:
22505286
[PubMed - indexed for MEDLINE]
14.

Zolmitriptan: a novel portal hypotensive agent which synergizes with propranolol in lowering portal pressure.

Reboredo M, Chang HC, Barbero R, Rodríguez-Ortigosa CM, Pérez-Vizcaíno F, Morán A, García M, Banales JM, Carreño N, Alegre F, Herrero I, Quiroga J, Prieto J, Sangro B.

PLoS One. 2013;8(1):e52683. doi: 10.1371/journal.pone.0052683. Epub 2013 Jan 16.

PMID:
23341903
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Droxidopa, an oral norepinephrine precursor, improves hemodynamic and renal alterations of portal hypertensive rats.

Coll M, Rodriguez S, Raurell I, Ezkurdia N, Brull A, Augustin S, Guardia J, Esteban R, Martell M, Genescà J.

Hepatology. 2012 Nov;56(5):1849-60. doi: 10.1002/hep.25845. Epub 2012 Oct 14.

PMID:
22610782
[PubMed - indexed for MEDLINE]
16.

Role of adenylate and guanylate cyclases in beta1-, beta2-, and beta3-adrenoceptor-mediated relaxation of internal anal sphincter smooth muscle.

Li F, De Godoy M, Rattan S.

J Pharmacol Exp Ther. 2004 Mar;308(3):1111-20. Epub 2004 Jan 7.

PMID:
14711933
[PubMed - indexed for MEDLINE]
Free Article
17.

Sorafenib targets dysregulated Rho kinase expression and portal hypertension in rats with secondary biliary cirrhosis.

Hennenberg M, Trebicka J, Stark C, Kohistani AZ, Heller J, Sauerbruch T.

Br J Pharmacol. 2009 May;157(2):258-70. doi: 10.1111/j.1476-5381.2009.00158.x. Epub 2009 Mar 26.

PMID:
19338580
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Lack of effect of norfloxacin on hyperdynamic circulation in bile duct-ligated rats despite reduction of endothelial nitric oxide synthase function: result of unchanged vascular Rho-kinase?

Hennenberg M, Trebicka J, Buecher D, Heller J, Sauerbruch T.

Liver Int. 2009 Jul;29(6):933-41. doi: 10.1111/j.1478-3231.2009.02010.x. Epub 2009 Mar 20.

PMID:
19490424
[PubMed - indexed for MEDLINE]
19.

Hepatic and HSC-specific sorafenib effects in rats with established secondary biliary cirrhosis.

Hennenberg M, Trebicka J, Kohistani Z, Stark C, Nischalke HD, Krämer B, Körner C, Klein S, Granzow M, Fischer HP, Heller J, Sauerbruch T.

Lab Invest. 2011 Feb;91(2):241-51. doi: 10.1038/labinvest.2010.148. Epub 2010 Oct 4.

PMID:
20921950
[PubMed - indexed for MEDLINE]
Free Article
20.

Amelioration of portal hypertension and the hyperdynamic circulatory syndrome in cirrhotic rats by neuropeptide Y via pronounced splanchnic vasoaction.

Moleda L, Trebicka J, Dietrich P, Gäbele E, Hellerbrand C, Straub RH, Sauerbruch T, Schoelmerich J, Wiest R.

Gut. 2011 Aug;60(8):1122-32. doi: 10.1136/gut.2010.226407. Epub 2011 Feb 12.

PMID:
21317421
[PubMed - indexed for MEDLINE]

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