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Results: 1 to 20 of 109

1.

Cells deficient in the base excision repair protein, DNA polymerase beta, are hypersensitive to oxaliplatin chemotherapy.

Yang J, Parsons J, Nicolay NH, Caporali S, Harrington CF, Singh R, Finch D, D'Atri S, Farmer PB, Johnston PG, McKenna WG, Dianov G, Sharma RA.

Oncogene. 2010 Jan 21;29(3):463-8. doi: 10.1038/onc.2009.327. Epub 2009 Oct 19.

PMID:
19838217
[PubMed - indexed for MEDLINE]
2.

Human colon cancer cells surviving high doses of cisplatin or oxaliplatin in vitro are not defective in DNA mismatch repair proteins.

Sergent C, Franco N, Chapusot C, Lizard-Nacol S, Isambert N, Correia M, Chauffert B.

Cancer Chemother Pharmacol. 2002 Jun;49(6):445-52. Epub 2002 Apr 20.

PMID:
12107548
[PubMed - indexed for MEDLINE]
3.

A role for polymerase eta in the cellular tolerance to cisplatin-induced damage.

Albertella MR, Green CM, Lehmann AR, O'Connor MJ.

Cancer Res. 2005 Nov 1;65(21):9799-806.

PMID:
16267001
[PubMed - indexed for MEDLINE]
Free Article
4.

Hypersensitivity of DNA polymerase beta null mouse fibroblasts reflects accumulation of cytotoxic repair intermediates from site-specific alkyl DNA lesions.

Horton JK, Joyce-Gray DF, Pachkowski BF, Swenberg JA, Wilson SH.

DNA Repair (Amst). 2003 Jan 2;2(1):27-48.

PMID:
12509266
[PubMed - indexed for MEDLINE]
5.

The efficiency and fidelity of translesion synthesis past cisplatin and oxaliplatin GpG adducts by human DNA polymerase beta.

Vaisman A, Chaney SG.

J Biol Chem. 2000 Apr 28;275(17):13017-25.

PMID:
10777605
[PubMed - indexed for MEDLINE]
Free Article
6.

In vitro studies on the mechanisms of oxaliplatin resistance.

Hector S, Bolanowska-Higdon W, Zdanowicz J, Hitt S, Pendyala L.

Cancer Chemother Pharmacol. 2001 Nov;48(5):398-406.

PMID:
11761458
[PubMed - indexed for MEDLINE]
7.

'Knock down' of DNA polymerase beta by RNA interference: recapitulation of null phenotype.

Polosina YY, Rosenquist TA, Grollman AP, Miller H.

DNA Repair (Amst). 2004 Nov 2;3(11):1469-74.

PMID:
15380102
[PubMed - indexed for MEDLINE]
8.

DNA synthesis and dRPase activities of polymerase beta are both essential for single-nucleotide patch base excision repair in mammalian cell extracts.

Podlutsky AJ, Dianova II, Wilson SH, Bohr VA, Dianov GL.

Biochemistry. 2001 Jan 23;40(3):809-13.

PMID:
11170398
[PubMed - indexed for MEDLINE]
9.

DNA polymerases beta and lambda mediate overlapping and independent roles in base excision repair in mouse embryonic fibroblasts.

Braithwaite EK, Kedar PS, Stumpo DJ, Bertocci B, Freedman JH, Samson LD, Wilson SH.

PLoS One. 2010 Aug 18;5(8):e12229. doi: 10.1371/journal.pone.0012229.

PMID:
20805875
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Involvement of DNA polymerase beta in protection against the cytotoxicity of oxidative DNA damage.

Horton JK, Baker A, Berg BJ, Sobol RW, Wilson SH.

DNA Repair (Amst). 2002 Apr 29;1(4):317-33.

PMID:
12509250
[PubMed - indexed for MEDLINE]
11.

The role of base excision repair in the sensitivity and resistance to temozolomide-mediated cell death.

Trivedi RN, Almeida KH, Fornsaglio JL, Schamus S, Sobol RW.

Cancer Res. 2005 Jul 15;65(14):6394-400.

PMID:
16024643
[PubMed - indexed for MEDLINE]
Free Article
12.

MSH3 expression does not influence the sensitivity of colon cancer HCT116 cell line to oxaliplatin and poly(ADP-ribose) polymerase (PARP) inhibitor as monotherapy or in combination.

Tentori L, Muzi A, Dorio AS, Dolci S, Campolo F, Vernole P, Lacal PM, Praz F, Graziani G.

Cancer Chemother Pharmacol. 2013 Jul;72(1):117-25. doi: 10.1007/s00280-013-2175-0. Epub 2013 May 1.

PMID:
23636450
[PubMed - indexed for MEDLINE]
13.

MSH3 mismatch repair protein regulates sensitivity to cytotoxic drugs and a histone deacetylase inhibitor in human colon carcinoma cells.

Park JM, Huang S, Tougeron D, Sinicrope FA.

PLoS One. 2013 May 28;8(5):e65369. doi: 10.1371/journal.pone.0065369. Print 2013.

PMID:
23724141
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Efficiency of extension of mismatched primer termini across from cisplatin and oxaliplatin adducts by human DNA polymerases beta and eta in vitro.

Bassett E, Vaisman A, Havener JM, Masutani C, Hanaoka F, Chaney SG.

Biochemistry. 2003 Dec 9;42(48):14197-206.

PMID:
14640687
[PubMed - indexed for MEDLINE]
15.

Mammalian DNA beta-polymerase in base excision repair of alkylation damage.

Sobol RW, Wilson SH.

Prog Nucleic Acid Res Mol Biol. 2001;68:57-74. Review.

PMID:
11554313
[PubMed - indexed for MEDLINE]
16.

DNA polymerase β as a novel target for chemotherapeutic intervention of colorectal cancer.

Jaiswal AS, Banerjee S, Aneja R, Sarkar FH, Ostrov DA, Narayan S.

PLoS One. 2011 Feb 2;6(2):e16691. doi: 10.1371/journal.pone.0016691.

PMID:
21311763
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Frameshifts and deletions during in vitro translesion synthesis past Pt-DNA adducts by DNA polymerases beta and eta.

Bassett E, Vaisman A, Tropea KA, McCall CM, Masutani C, Hanaoka F, Chaney SG.

DNA Repair (Amst). 2002 Dec 5;1(12):1003-16.

PMID:
12531010
[PubMed - indexed for MEDLINE]
18.

Protein interactions with platinum-DNA adducts: from structure to function.

Chaney SG, Campbell SL, Temple B, Bassett E, Wu Y, Faldu M.

J Inorg Biochem. 2004 Oct;98(10):1551-9.

PMID:
15458816
[PubMed - indexed for MEDLINE]
19.

Cells deficient in DNA polymerase beta are hypersensitive to alkylating agent-induced apoptosis and chromosomal breakage.

Ochs K, Sobol RW, Wilson SH, Kaina B.

Cancer Res. 1999 Apr 1;59(7):1544-51.

PMID:
10197627
[PubMed - indexed for MEDLINE]
Free Article
20.

Recognition and processing of cisplatin- and oxaliplatin-DNA adducts.

Chaney SG, Campbell SL, Bassett E, Wu Y.

Crit Rev Oncol Hematol. 2005 Jan;53(1):3-11. Review.

PMID:
15607931
[PubMed - indexed for MEDLINE]

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