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Results: 1 to 20 of 147

1.

Ago-TNRC6 triggers microRNA-mediated decay by promoting two deadenylation steps.

Chen CY, Zheng D, Xia Z, Shyu AB.

Nat Struct Mol Biol. 2009 Nov;16(11):1160-6. doi: 10.1038/nsmb.1709. Epub 2009 Oct 18.

PMID:
19838187
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Mammalian GW182 contains multiple Argonaute-binding sites and functions in microRNA-mediated translational repression.

Takimoto K, Wakiyama M, Yokoyama S.

RNA. 2009 Jun;15(6):1078-89. doi: 10.1261/rna.1363109. Epub 2009 Apr 27.

PMID:
19398495
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.

Fabian MR, Mathonnet G, Sundermeier T, Mathys H, Zipprich JT, Svitkin YV, Rivas F, Jinek M, Wohlschlegel J, Doudna JA, Chen CY, Shyu AB, Yates JR 3rd, Hannon GJ, Filipowicz W, Duchaine TF, Sonenberg N.

Mol Cell. 2009 Sep 24;35(6):868-80. doi: 10.1016/j.molcel.2009.08.004. Epub 2009 Aug 27.

PMID:
19716330
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

CCR4-NOT deadenylates mRNA associated with RNA-induced silencing complexes in human cells.

Piao X, Zhang X, Wu L, Belasco JG.

Mol Cell Biol. 2010 Mar;30(6):1486-94. doi: 10.1128/MCB.01481-09. Epub 2010 Jan 11.

PMID:
20065043
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4-NOT.

Fabian MR, Cieplak MK, Frank F, Morita M, Green J, Srikumar T, Nagar B, Yamamoto T, Raught B, Duchaine TF, Sonenberg N.

Nat Struct Mol Biol. 2011 Oct 7;18(11):1211-7. doi: 10.1038/nsmb.2149. Erratum in: Nat Struct Mol Biol. 2012 Mar;19(3):364.

PMID:
21984185
[PubMed - indexed for MEDLINE]
6.

Functional dissection of the human TNRC6 (GW182-related) family of proteins.

Baillat D, Shiekhattar R.

Mol Cell Biol. 2009 Aug;29(15):4144-55. doi: 10.1128/MCB.00380-09. Epub 2009 May 26.

PMID:
19470757
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The chicken or the egg: microRNA-mediated regulation of mRNA translation or mRNA stability.

Omer AD, Janas MM, Novina CD.

Mol Cell. 2009 Sep 24;35(6):739-40. doi: 10.1016/j.molcel.2009.09.003.

PMID:
19782024
[PubMed - indexed for MEDLINE]
Free Article
8.

Deadenylation is a widespread effect of miRNA regulation.

Eulalio A, Huntzinger E, Nishihara T, Rehwinkel J, Fauser M, Izaurralde E.

RNA. 2009 Jan;15(1):21-32. doi: 10.1261/rna.1399509. Epub 2008 Nov 24.

PMID:
19029310
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes.

Behm-Ansmant I, Rehwinkel J, Doerks T, Stark A, Bork P, Izaurralde E.

Genes Dev. 2006 Jul 15;20(14):1885-98. Epub 2006 Jun 30.

PMID:
16815998
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins.

Lazzaretti D, Tournier I, Izaurralde E.

RNA. 2009 Jun;15(6):1059-66. doi: 10.1261/rna.1606309. Epub 2009 Apr 21.

PMID:
19383768
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

miRISC recruits decapping factors to miRNA targets to enhance their degradation.

Nishihara T, Zekri L, Braun JE, Izaurralde E.

Nucleic Acids Res. 2013 Oct;41(18):8692-705. doi: 10.1093/nar/gkt619. Epub 2013 Jul 17.

PMID:
23863838
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

microRNA/Argonaute 2 regulates nonsense-mediated messenger RNA decay.

Choe J, Cho H, Lee HC, Kim YK.

EMBO Rep. 2010 May;11(5):380-6. doi: 10.1038/embor.2010.44. Epub 2010 Apr 16.

PMID:
20395958
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

The role of GW182 proteins in miRNA-mediated gene silencing.

Braun JE, Huntzinger E, Izaurralde E.

Adv Exp Med Biol. 2013;768:147-63. doi: 10.1007/978-1-4614-5107-5_9. Review.

PMID:
23224969
[PubMed - indexed for MEDLINE]
14.

A molecular link between miRISCs and deadenylases provides new insight into the mechanism of gene silencing by microRNAs.

Braun JE, Huntzinger E, Izaurralde E.

Cold Spring Harb Perspect Biol. 2012 Dec 1;4(12). pii: a012328. doi: 10.1101/cshperspect.a012328. Review.

PMID:
23209154
[PubMed - indexed for MEDLINE]
15.

Mapping of Ago2-GW182 functional interactions.

Yao B, Li S, Lian SL, Fritzler MJ, Chan EK.

Methods Mol Biol. 2011;725:45-62. doi: 10.1007/978-1-61779-046-1_4.

PMID:
21528446
[PubMed - indexed for MEDLINE]
16.

Function of GW182 and GW bodies in siRNA and miRNA pathways.

Yao B, Li S, Chan EK.

Adv Exp Med Biol. 2013;768:71-96. doi: 10.1007/978-1-4614-5107-5_6. Review.

PMID:
23224966
[PubMed - indexed for MEDLINE]
17.

Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover.

Yamashita A, Chang TC, Yamashita Y, Zhu W, Zhong Z, Chen CY, Shyu AB.

Nat Struct Mol Biol. 2005 Dec;12(12):1054-63. Epub 2005 Nov 13.

PMID:
16284618
[PubMed - indexed for MEDLINE]
18.

Defining a new role of GW182 in maintaining miRNA stability.

Yao B, La LB, Chen YC, Chang LJ, Chan EK.

EMBO Rep. 2012 Dec;13(12):1102-8. doi: 10.1038/embor.2012.160. Epub 2012 Oct 23.

PMID:
23090477
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Let-7 microRNA-mediated mRNA deadenylation and translational repression in a mammalian cell-free system.

Wakiyama M, Takimoto K, Ohara O, Yokoyama S.

Genes Dev. 2007 Aug 1;21(15):1857-62. Erratum in: Genes Dev. 2007 Oct 1;21(19):2509.

PMID:
17671087
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells.

Zheng D, Ezzeddine N, Chen CY, Zhu W, He X, Shyu AB.

J Cell Biol. 2008 Jul 14;182(1):89-101. doi: 10.1083/jcb.200801196.

PMID:
18625844
[PubMed - indexed for MEDLINE]
Free PMC Article

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