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Results: 1 to 20 of 68

1.
2.

Pattern of genes influenced by conditional expression of the transcription factors HNF6, HNF4alpha and HNF1beta in a pancreatic beta-cell line.

Thomas H, Senkel S, Erdmann S, Arndt T, Turan G, Klein-Hitpass L, Ryffel GU.

Nucleic Acids Res. 2004 Nov 1;32(19):e150.

PMID:
15520459
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Tissue-specific transcription factor HNF4alpha inhibits cell proliferation and induces apoptosis in the pancreatic INS-1 beta-cell line.

Erdmann S, Senkel S, Arndt T, Lucas B, Lausen J, Klein-Hitpass L, Ryffel GU, Thomas H.

Biol Chem. 2007 Jan;388(1):91-106.

PMID:
17214554
[PubMed - indexed for MEDLINE]
4.

Optimization of tetracycline-responsive recombinant protein production and effect on cell growth and ER stress in mammalian cells.

Jones J, Nivitchanyong T, Giblin C, Ciccarone V, Judd D, Gorfien S, Krag SS, Betenbaugh MJ.

Biotechnol Bioeng. 2005 Sep 20;91(6):722-32.

PMID:
15981277
[PubMed - indexed for MEDLINE]
5.

Hepatocyte nuclear factor 4alpha regulates the expression of pancreatic beta -cell genes implicated in glucose metabolism and nutrient-induced insulin secretion.

Wang H, Maechler P, Antinozzi PA, Hagenfeldt KA, Wollheim CB.

J Biol Chem. 2000 Nov 17;275(46):35953-9.

PMID:
10967120
[PubMed - indexed for MEDLINE]
Free Article
6.

HNF4alpha and HNF1alpha dysfunction as a molecular rational for cyclosporine induced posttransplantation diabetes mellitus.

Borlak J, Niehof M.

PLoS One. 2009;4(3):e4662. doi: 10.1371/journal.pone.0004662. Epub 2009 Mar 2.

PMID:
19252740
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Functional characterization of the HNF4alpha isoform (HNF4alpha8) expressed in pancreatic beta-cells.

Ihara A, Yamagata K, Nammo T, Miura A, Yuan M, Tanaka T, Sladek FM, Matsuzawa Y, Miyagawa J, Shimomura I.

Biochem Biophys Res Commun. 2005 Apr 15;329(3):984-90.

PMID:
15752752
[PubMed - indexed for MEDLINE]
8.

Down-regulation of hepatic nuclear factor 4alpha on expression of human hepatic stimulator substance via its action on the proximal promoter in HepG2 cells.

Guo D, Dong LY, Wu Y, Yang L, An W.

Biochem J. 2008 Oct 1;415(1):111-21. doi: 10.1042/BJ20080221.

PMID:
18513187
[PubMed - indexed for MEDLINE]
Free Article
9.

Conditional transformation of a pancreatic beta-cell line derived from transgenic mice expressing a tetracycline-regulated oncogene.

Efrat S, Fusco-DeMane D, Lemberg H, al Emran O, Wang X.

Proc Natl Acad Sci U S A. 1995 Apr 11;92(8):3576-80.

PMID:
7724601
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

HNF4alpha reduces proliferation of kidney cells and affects genes deregulated in renal cell carcinoma.

Lucas B, Grigo K, Erdmann S, Lausen J, Klein-Hitpass L, Ryffel GU.

Oncogene. 2005 Sep 22;24(42):6418-31.

PMID:
16007190
[PubMed - indexed for MEDLINE]
12.

H2S, endoplasmic reticulum stress, and apoptosis of insulin-secreting beta cells.

Yang G, Yang W, Wu L, Wang R.

J Biol Chem. 2007 Jun 1;282(22):16567-76. Epub 2007 Apr 12.

PMID:
17430888
[PubMed - indexed for MEDLINE]
Free Article
13.

DNA damage and cytotoxicity in pancreatic beta-cells expressing human CYP2E1.

Lees Murdock DJ, Barnett YA, Barnett CR.

Biochem Pharmacol. 2004 Aug 1;68(3):523-30.

PMID:
15242818
[PubMed - indexed for MEDLINE]
14.

On the use of the T-REx tetracycline-inducible gene expression system in vivo.

Dobrovolsky VN, Heflich RH.

Biotechnol Bioeng. 2007 Oct 15;98(3):719-23.

PMID:
17421042
[PubMed - indexed for MEDLINE]
15.

Tumor-specific adenovirus-mediated PUMA gene transfer using the survivin promoter enhances radiosensitivity of breast cancer cells in vitro and in vivo.

Wang R, Wang X, Li B, Lin F, Dong K, Gao P, Zhang HZ.

Breast Cancer Res Treat. 2009 Sep;117(1):45-54. doi: 10.1007/s10549-008-0163-6. Epub 2008 Sep 13.

PMID:
18791823
[PubMed - indexed for MEDLINE]
16.

A self-inactivating retrovector incorporating the IL-2 promoter for activation-induced transgene expression in genetically engineered T-cells.

Jaalouk DE, Lejeune L, Couture C, Galipeau J.

Virol J. 2006 Nov 21;3:97.

PMID:
17118192
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Dominant-negative suppression of HNF-1 alpha results in mitochondrial dysfunction, INS-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell death.

Wobser H, Düssmann H, Kögel D, Wang H, Reimertz C, Wollheim CB, Byrne MM, Prehn JH.

J Biol Chem. 2002 Feb 22;277(8):6413-21. Epub 2001 Nov 27.

PMID:
11724785
[PubMed - indexed for MEDLINE]
Free Article
18.

Inducible and reversible transgene expression in human stem cells after efficient and stable gene transfer.

Zhou BY, Ye Z, Chen G, Gao ZP, Zhang YA, Cheng L.

Stem Cells. 2007 Mar;25(3):779-89. Epub 2006 Dec 7.

PMID:
17158240
[PubMed - indexed for MEDLINE]
Free Article
19.

Hypoxic regulation of PFKFB-3 and PFKFB-4 gene expression in gastric and pancreatic cancer cell lines and expression of PFKFB genes in gastric cancers.

Bobarykina AY, Minchenko DO, Opentanova IL, Moenner M, Caro J, Esumi H, Minchenko OH.

Acta Biochim Pol. 2006;53(4):789-99. Epub 2006 Dec 4.

PMID:
17143338
[PubMed - indexed for MEDLINE]
Free Article
20.

Growth arrest- and DNA-damage-inducible 45beta gene inhibits c-Jun N-terminal kinase and extracellular signal-regulated kinase and decreases IL-1beta-induced apoptosis in insulin-producing INS-1E cells.

Larsen CM, Døssing MG, Papa S, Franzoso G, Billestrup N, Mandrup-Poulsen T.

Diabetologia. 2006 May;49(5):980-9. Epub 2006 Mar 10.

PMID:
16528573
[PubMed - indexed for MEDLINE]

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