Format
Sort by

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 115

1.

Gene therapy with neurogenin 3 and betacellulin reverses major metabolic problems in insulin-deficient diabetic mice.

Yechoor V, Liu V, Paul A, Lee J, Buras E, Ozer K, Samson S, Chan L.

Endocrinology. 2009 Nov;150(11):4863-73. doi: 10.1210/en.2009-0527. Epub 2009 Oct 9.

2.

Neo-islet formation in liver of diabetic mice by helper-dependent adenoviral vector-mediated gene transfer.

Li R, Oka K, Yechoor V.

J Vis Exp. 2012 Oct 10;(68). pii: 4321. doi: 10.3791/4321.

3.

Hydrodynamics-based transfection of the combination of betacellulin and neurogenic differentiation 1 DNA ameliorates hyperglycemia in mice with streptozotocin-induced diabetes.

Sung CM, Yeh CT, Shiau SS, Liang CK, Chang ML.

Diabetes Technol Ther. 2011 May;13(5):519-25. doi: 10.1089/dia.2010.0140. Epub 2011 Mar 15.

PMID:
21406008
4.

NeuroD-betacellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice.

Kojima H, Fujimiya M, Matsumura K, Younan P, Imaeda H, Maeda M, Chan L.

Nat Med. 2003 May;9(5):596-603. Epub 2003 Apr 21.

PMID:
12704384
5.

Neurogenin3 is sufficient for transdetermination of hepatic progenitor cells into neo-islets in vivo but not transdifferentiation of hepatocytes.

Yechoor V, Liu V, Espiritu C, Paul A, Oka K, Kojima H, Chan L.

Dev Cell. 2009 Mar;16(3):358-73. doi: 10.1016/j.devcel.2009.01.012.

6.
7.

PD-L1-driven tolerance protects neurogenin3-induced islet neogenesis to reverse established type 1 diabetes in NOD mice.

Li R, Lee J, Kim MS, Liu V, Moulik M, Li H, Yi Q, Xie A, Chen W, Yang L, Li Y, Tsai TH, Oka K, Chan L, Yechoor V.

Diabetes. 2015 Feb;64(2):529-40. doi: 10.2337/db13-1737. Epub 2014 Oct 20. Erratum in: Diabetes. 2015 Jul;64(7):2685.

8.

Long-term reversal of diabetes in non-obese diabetic mice by liver-directed gene therapy.

Ren B, O'Brien BA, Byrne MR, Ch'ng E, Gatt PN, Swan MA, Nassif NT, Wei MQ, Gijsbers R, Debyser Z, Simpson AM.

J Gene Med. 2013 Jan;15(1):28-41. doi: 10.1002/jgm.2692.

PMID:
23293075
9.

Transplantation of betacellulin-transduced islets improves glucose intolerance in diabetic mice.

Song MY, Bae UJ, Jang KY, Park BH.

Exp Mol Med. 2014 May 30;46:e98. doi: 10.1038/emm.2014.24.

10.

Gene therapy with neurogenin3, betacellulin and SOCS1 reverses diabetes in NOD mice.

Li R, Buras E, Lee J, Liu R, Liu V, Espiritu C, Ozer K, Thompson B, Nally L, Yuan G, Oka K, Chang B, Samson S, Yechoor V, Chan L.

Gene Ther. 2015 Nov;22(11):876-82. doi: 10.1038/gt.2015.62. Epub 2015 Jul 14.

11.

Betacellulin overexpression in mesenchymal stem cells induces insulin secretion in vitro and ameliorates streptozotocin-induced hyperglycemia in rats.

Paz AH, Salton GD, Ayala-Lugo A, Gomes C, Terraciano P, Scalco R, Laurino CC, Passos EP, Schneider MR, Meurer L, Cirne-Lima E.

Stem Cells Dev. 2011 Feb;20(2):223-32. doi: 10.1089/scd.2009.0490. Epub 2010 Oct 26.

PMID:
20836700
12.

Betacellulin overexpression in transgenic mice improves glucose tolerance and enhances insulin secretion by isolated islets in vitro.

Dahlhoff M, Dames PM, Lechner A, Herbach N, van Bürck L, Wanke R, Wolf E, Schneider MR.

Mol Cell Endocrinol. 2009 Feb 27;299(2):188-93. doi: 10.1016/j.mce.2008.11.022. Epub 2008 Nov 28.

PMID:
19100309
13.
14.

Reversal of streptozotocin-induced diabetes in rats by gene therapy with betacellulin and pancreatic duodenal homeobox-1.

Chen S, Ding J, Yu C, Yang B, Wood DR, Grayburn PA.

Gene Ther. 2007 Jul;14(14):1102-10. Epub 2007 Apr 26.

PMID:
17460716
15.
16.

Characterization of vector-based delivery of neurogenin-3 in murine diabetes.

Phillips N, Kay MA.

Hum Gene Ther. 2014 Jul;25(7):651-61. doi: 10.1089/hum.2013.206. Epub 2014 Apr 14.

17.

Remission of diabetes by beta-cell regeneration in diabetic mice treated with a recombinant adenovirus expressing betacellulin.

Shin S, Li N, Kobayashi N, Yoon JW, Jun HS.

Mol Ther. 2008 May;16(5):854-61. doi: 10.1038/mt.2008.22. Epub 2008 Mar 18. Erratum in: Mol Ther. 2008 Jul;16(7):1347.

PMID:
18388935
18.

Notch signalling suppresses apoptosis in adult human and mouse pancreatic islet cells.

Dror V, Nguyen V, Walia P, Kalynyak TB, Hill JA, Johnson JD.

Diabetologia. 2007 Dec;50(12):2504-15. Epub 2007 Oct 6.

PMID:
17922104
19.

The orphan nuclear receptor small heterodimer partner negatively regulates pancreatic beta cell survival and hyperglycemia in multiple low-dose streptozotocin-induced type 1 diabetic mice.

Noh JR, Hwang JH, Kim YH, Kim KS, Gang GT, Kim SW, Kim DK, Shong M, Lee IK, Choi HS, Lee CH.

Int J Biochem Cell Biol. 2013 Aug;45(8):1538-45. doi: 10.1016/j.biocel.2013.05.004. Epub 2013 May 13.

PMID:
23680671
20.

PDX1- and NGN3-mediated in vitro reprogramming of human bone marrow-derived mesenchymal stromal cells into pancreatic endocrine lineages.

Limbert C, Päth G, Ebert R, Rothhammer V, Kassem M, Jakob F, Seufert J.

Cytotherapy. 2011 Aug;13(7):802-13. doi: 10.3109/14653249.2011.571248. Epub 2011 Apr 21.

PMID:
21506889
Items per page

Supplemental Content

Write to the Help Desk