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Items: 1 to 20 of 162

1.

Long-term effects of losartan on structure and function of the thoracic aorta in a mouse model of Marfan syndrome.

Yang HH, Kim JM, Chum E, van Breemen C, Chung AW.

Br J Pharmacol. 2009 Nov;158(6):1503-12. doi: 10.1111/j.1476-5381.2009.00443.x. Epub 2009 Oct 8.

2.

Effectiveness of combination of losartan potassium and doxycycline versus single-drug treatments in the secondary prevention of thoracic aortic aneurysm in Marfan syndrome.

Yang HH, Kim JM, Chum E, van Breemen C, Chung AW.

J Thorac Cardiovasc Surg. 2010 Aug;140(2):305-312.e2. doi: 10.1016/j.jtcvs.2009.10.039. Epub 2010 Feb 26.

PMID:
20189193
3.

Endothelial dysfunction and compromised eNOS/Akt signaling in the thoracic aorta during the progression of Marfan syndrome.

Chung AW, Au Yeung K, Cortes SF, Sandor GG, Judge DP, Dietz HC, van Breemen C.

Br J Pharmacol. 2007 Apr;150(8):1075-83. Epub 2007 Mar 5.

4.

Long-term doxycycline is more effective than atenolol to prevent thoracic aortic aneurysm in marfan syndrome through the inhibition of matrix metalloproteinase-2 and -9.

Chung AW, Yang HH, Radomski MW, van Breemen C.

Circ Res. 2008 Apr 25;102(8):e73-85. doi: 10.1161/CIRCRESAHA.108.174367. Epub 2008 Apr 3.

6.
7.

Doxycycline delays aneurysm rupture in a mouse model of Marfan syndrome.

Xiong W, Knispel RA, Dietz HC, Ramirez F, Baxter BT.

J Vasc Surg. 2008 Jan;47(1):166-72; discussion 172. doi: 10.1016/j.jvs.2007.09.016.

8.

Dimorphic effects of transforming growth factor-β signaling during aortic aneurysm progression in mice suggest a combinatorial therapy for Marfan syndrome.

Cook JR, Clayton NP, Carta L, Galatioto J, Chiu E, Smaldone S, Nelson CA, Cheng SH, Wentworth BM, Ramirez F.

Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):911-7. doi: 10.1161/ATVBAHA.114.305150. Epub 2015 Jan 22.

9.

Impaired vascular contractility and aortic wall degeneration in fibulin-4 deficient mice: effect of angiotensin II type 1 (AT1) receptor blockade.

Moltzer E, te Riet L, Swagemakers SM, van Heijningen PM, Vermeij M, van Veghel R, Bouhuizen AM, van Esch JH, Lankhorst S, Ramnath NW, de Waard MC, Duncker DJ, van der Spek PJ, Rouwet EV, Danser AH, Essers J.

PLoS One. 2011;6(8):e23411. doi: 10.1371/journal.pone.0023411. Epub 2011 Aug 9.

10.

miR-29b participates in early aneurysm development in Marfan syndrome.

Merk DR, Chin JT, Dake BA, Maegdefessel L, Miller MO, Kimura N, Tsao PS, Iosef C, Berry GJ, Mohr FW, Spin JM, Alvira CM, Robbins RC, Fischbein MP.

Circ Res. 2012 Jan 20;110(2):312-24. doi: 10.1161/CIRCRESAHA.111.253740. Epub 2011 Nov 23.

11.

Pravastatin reduces Marfan aortic dilation.

McLoughlin D, McGuinness J, Byrne J, Terzo E, Huuskonen V, McAllister H, Black A, Kearney S, Kay E, Hill AD, Dietz HC, Redmond JM.

Circulation. 2011 Sep 13;124(11 Suppl):S168-73. doi: 10.1161/CIRCULATIONAHA.110.012187.

12.

Vasomotor dysfunction in the thoracic aorta of Marfan syndrome is associated with accumulation of oxidative stress.

Yang HH, van Breemen C, Chung AW.

Vascul Pharmacol. 2010 Jan-Feb;52(1-2):37-45. doi: 10.1016/j.vph.2009.10.005. Epub 2009 Oct 29.

PMID:
19879959
13.

Altered tissue behavior of a non-aneurysmal descending thoracic aorta in the mouse model of Marfan syndrome.

Haskett D, Doyle JJ, Gard C, Chen H, Ball C, Estabrook MA, Encinas AC, Dietz HC, Utzinger U, Vande Geest JP, Azhar M.

Cell Tissue Res. 2012 Jan;347(1):267-77. doi: 10.1007/s00441-011-1270-y. Epub 2011 Nov 22.

PMID:
22105919
14.

Aortic remodeling after transverse aortic constriction in mice is attenuated with AT1 receptor blockade.

Kuang SQ, Geng L, Prakash SK, Cao JM, Guo S, Villamizar C, Kwartler CS, Peters AM, Brasier AR, Milewicz DM.

Arterioscler Thromb Vasc Biol. 2013 Sep;33(9):2172-9. doi: 10.1161/ATVBAHA.113.301624. Epub 2013 Jul 18.

15.

MMP-2 regulates Erk1/2 phosphorylation and aortic dilatation in Marfan syndrome.

Xiong W, Meisinger T, Knispel R, Worth JM, Baxter BT.

Circ Res. 2012 Jun 8;110(12):e92-e101. doi: 10.1161/CIRCRESAHA.112.268268. Epub 2012 May 1.

16.

Dysfunction of endothelial and smooth muscle cells in small arteries of a mouse model of Marfan syndrome.

Syyong HT, Chung AW, Yang HH, van Breemen C.

Br J Pharmacol. 2009 Nov;158(6):1597-608. doi: 10.1111/j.1476-5381.2009.00439.x. Epub 2009 Oct 8.

17.

The role of β-arrestin2-dependent signaling in thoracic aortic aneurysm formation in a murine model of Marfan syndrome.

Wisler JW, Harris EM, Raisch M, Mao L, Kim J, Rockman HA, Lefkowitz RJ.

Am J Physiol Heart Circ Physiol. 2015 Nov;309(9):H1516-27. doi: 10.1152/ajpheart.00291.2015. Epub 2015 Sep 14.

18.

Losartan improves aortic endothelium-dependent relaxation via proline-rich tyrosine kinase 2/Src/Akt pathway in type 2 diabetic Goto-Kakizaki rats.

Nemoto S, Kobayashi T, Taguchi K, Matsumoto T, Kamata K.

Am J Physiol Heart Circ Physiol. 2011 Dec;301(6):H2383-94. doi: 10.1152/ajpheart.00178.2011. Epub 2011 Sep 16.

19.

Angiotensin II type 2 receptors contribute to vascular responses in spontaneously hypertensive rats treated with angiotensin II type 1 receptor antagonists.

Cosentino F, Savoia C, De Paolis P, Francia P, Russo A, Maffei A, Venturelli V, Schiavoni M, Lembo G, Volpe M.

Am J Hypertens. 2005 Apr;18(4 Pt 1):493-9.

PMID:
15831358
20.

Enhanced caspase activity contributes to aortic wall remodeling and early aneurysm development in a murine model of Marfan syndrome.

Emrich FC, Okamura H, Dalal AR, Penov K, Merk DR, Raaz U, Hennigs JK, Chin JT, Miller MO, Pedroza AJ, Craig JK, Koyano TK, Blankenberg FG, Connolly AJ, Mohr FW, Alvira CM, Rabinovitch M, Fischbein MP.

Arterioscler Thromb Vasc Biol. 2015 Jan;35(1):146-54. doi: 10.1161/ATVBAHA.114.304364. Epub 2014 Oct 30.

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