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Results: 1 to 20 of 121

1.

Titin isoforms, extracellular matrix, and global chamber remodeling in experimental dilated cardiomyopathy: functional implications and mechanistic insight.

Jaber WA, Maniu C, Krysiak J, Shapiro BP, Meyer DM, Linke WA, Redfield MM.

Circ Heart Fail. 2008 Sep;1(3):192-9. doi: 10.1161/CIRCHEARTFAILURE.108.768465. Epub 2008 Jun 25.

PMID:
19808289
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Altered titin expression, myocardial stiffness, and left ventricular function in patients with dilated cardiomyopathy.

Nagueh SF, Shah G, Wu Y, Torre-Amione G, King NM, Lahmers S, Witt CC, Becker K, Labeit S, Granzier HL.

Circulation. 2004 Jul 13;110(2):155-62. Epub 2004 Jul 6.

PMID:
15238456
[PubMed - indexed for MEDLINE]
Free Article
3.

Changes in titin isoform expression in pacing-induced cardiac failure give rise to increased passive muscle stiffness.

Wu Y, Bell SP, Trombitas K, Witt CC, Labeit S, LeWinter MM, Granzier H.

Circulation. 2002 Sep 10;106(11):1384-9.

PMID:
12221057
[PubMed - indexed for MEDLINE]
Free Article
4.

Hypophosphorylation of the Stiff N2B titin isoform raises cardiomyocyte resting tension in failing human myocardium.

Borbély A, Falcao-Pires I, van Heerebeek L, Hamdani N, Edes I, Gavina C, Leite-Moreira AF, Bronzwaer JG, Papp Z, van der Velden J, Stienen GJ, Paulus WJ.

Circ Res. 2009 Mar 27;104(6):780-6. doi: 10.1161/CIRCRESAHA.108.193326. Epub 2009 Jan 29.

PMID:
19179657
[PubMed - indexed for MEDLINE]
Free Article
5.

Passive stiffness changes caused by upregulation of compliant titin isoforms in human dilated cardiomyopathy hearts.

Makarenko I, Opitz CA, Leake MC, Neagoe C, Kulke M, Gwathmey JK, del Monte F, Hajjar RJ, Linke WA.

Circ Res. 2004 Oct 1;95(7):708-16. Epub 2004 Sep 2.

PMID:
15345656
[PubMed - indexed for MEDLINE]
Free Article
6.

Hyperphosphorylation of mouse cardiac titin contributes to transverse aortic constriction-induced diastolic dysfunction.

Hudson B, Hidalgo C, Saripalli C, Granzier H.

Circ Res. 2011 Sep 30;109(8):858-66. doi: 10.1161/CIRCRESAHA.111.246819. Epub 2011 Aug 11.

PMID:
21835910
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Titin isoform switch in ischemic human heart disease.

Neagoe C, Kulke M, del Monte F, Gwathmey JK, de Tombe PP, Hajjar RJ, Linke WA.

Circulation. 2002 Sep 10;106(11):1333-41.

PMID:
12221049
[PubMed - indexed for MEDLINE]
Free Article
8.

Deranged myofilament phosphorylation and function in experimental heart failure with preserved ejection fraction.

Hamdani N, Bishu KG, von Frieling-Salewsky M, Redfield MM, Linke WA.

Cardiovasc Res. 2013 Mar 1;97(3):464-71. doi: 10.1093/cvr/cvs353. Epub 2012 Dec 4.

PMID:
23213108
[PubMed - indexed for MEDLINE]
Free Article
9.

Cellular and molecular mechanisms of systolic and diastolic dysfunction in an avian model of dilated cardiomyopathy.

Wu Y, Tobias AH, Bell K, Barry W, Helmes M, Trombitas K, Tucker R, Campbell KB, Granzier HL.

J Mol Cell Cardiol. 2004 Jul;37(1):111-9.

PMID:
15242741
[PubMed - indexed for MEDLINE]
10.

Protein kinase G modulates human myocardial passive stiffness by phosphorylation of the titin springs.

Krüger M, Kötter S, Grützner A, Lang P, Andresen C, Redfield MM, Butt E, dos Remedios CG, Linke WA.

Circ Res. 2009 Jan 2;104(1):87-94. doi: 10.1161/CIRCRESAHA.108.184408. Epub 2008 Nov 20.

PMID:
19023132
[PubMed - indexed for MEDLINE]
Free Article
11.

Changes in titin and collagen underlie diastolic stiffness diversity of cardiac muscle.

Wu Y, Cazorla O, Labeit D, Labeit S, Granzier H.

J Mol Cell Cardiol. 2000 Dec;32(12):2151-62.

PMID:
11112991
[PubMed - indexed for MEDLINE]
12.

Differential expression of cardiac titin isoforms and modulation of cellular stiffness.

Cazorla O, Freiburg A, Helmes M, Centner T, McNabb M, Wu Y, Trombitás K, Labeit S, Granzier H.

Circ Res. 2000 Jan 7-21;86(1):59-67.

PMID:
10625306
[PubMed - indexed for MEDLINE]
Free Article
13.

Insulin signaling regulates cardiac titin properties in heart development and diabetic cardiomyopathy.

Krüger M, Babicz K, von Frieling-Salewsky M, Linke WA.

J Mol Cell Cardiol. 2010 May;48(5):910-6. doi: 10.1016/j.yjmcc.2010.02.012. Epub 2010 Feb 23.

PMID:
20184888
[PubMed - indexed for MEDLINE]
14.

Passive stiffness of myocardium from congenital heart disease and implications for diastole.

Chaturvedi RR, Herron T, Simmons R, Shore D, Kumar P, Sethia B, Chua F, Vassiliadis E, Kentish JC.

Circulation. 2010 Mar 2;121(8):979-88. doi: 10.1161/CIRCULATIONAHA.109.850677. Epub 2010 Feb 16.

PMID:
20159832
[PubMed - indexed for MEDLINE]
Free Article
15.

Plasticity of cardiac titin/connectin in heart development.

Opitz CA, Linke WA.

J Muscle Res Cell Motil. 2005;26(6-8):333-42.

PMID:
16465471
[PubMed - indexed for MEDLINE]
16.

Titin isoform switching is a major cardiac adaptive response in hibernating grizzly bears.

Nelson OL, Robbins CT, Wu Y, Granzier H.

Am J Physiol Heart Circ Physiol. 2008 Jul;295(1):H366-71. doi: 10.1152/ajpheart.00234.2008. Epub 2008 May 23.

PMID:
18502907
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Developmental changes in passive stiffness and myofilament Ca2+ sensitivity due to titin and troponin-I isoform switching are not critically triggered by birth.

Krüger M, Kohl T, Linke WA.

Am J Physiol Heart Circ Physiol. 2006 Aug;291(2):H496-506. Epub 2006 May 5. Erratum in: Am J Physiol Heart Circ Physiol. 2007 Jan;292(1):H726.

PMID:
16679402
[PubMed - indexed for MEDLINE]
Free Article
18.

Chronic heart failure selectively induces regional heterogeneity of insulin-responsive glucose transporters.

Ware B, Bevier M, Nishijima Y, Rogers S, Carnes CA, Lacombe VA.

Am J Physiol Regul Integr Comp Physiol. 2011 Nov;301(5):R1300-6. doi: 10.1152/ajpregu.00822.2010. Epub 2011 Aug 17.

PMID:
21849635
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Titin-isoform dependence of titin-actin interaction and its regulation by S100A1/Ca2+ in skinned myocardium.

Fukushima H, Chung CS, Granzier H.

J Biomed Biotechnol. 2010;2010:727239. doi: 10.1155/2010/727239. Epub 2010 Apr 14.

PMID:
20414336
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Development of dilated cardiomyopathy in Bmal1-deficient mice.

Lefta M, Campbell KS, Feng HZ, Jin JP, Esser KA.

Am J Physiol Heart Circ Physiol. 2012 Aug 15;303(4):H475-85. doi: 10.1152/ajpheart.00238.2012. Epub 2012 Jun 15.

PMID:
22707558
[PubMed - indexed for MEDLINE]
Free PMC Article

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