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Results: 1 to 20 of 79

1.

On-line coupling of anion exchange and ion-pair chromatography for measurement of intracellular triphosphate metabolites of reverse transcriptase inhibitors.

Kuklenyik Z, Martin A, Pau CP, Holder A, Youngpairoj AS, Zheng Q, Cong ME, Garcia-Lerma JG, Heneine W, Pirkle JL, Barr JR.

J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Nov 1;877(29):3659-66. doi: 10.1016/j.jchromb.2009.09.007. Epub 2009 Sep 11.

PMID:
19783232
[PubMed - indexed for MEDLINE]
2.

Simultaneous quantification of emtricitabine and tenofovir nucleotides in peripheral blood mononuclear cells using weak anion-exchange liquid chromatography coupled with tandem mass spectrometry.

Jansen RS, Rosing H, Kromdijk W, ter Heine R, Schellens JH, Beijnen JH.

J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Mar 1;878(7-8):621-7. doi: 10.1016/j.jchromb.2010.01.002. Epub 2010 Jan 14.

PMID:
20122883
[PubMed - indexed for MEDLINE]
3.

In vitro evaluation of the anti-HIV activity and metabolic interactions of tenofovir and emtricitabine.

Borroto-Esoda K, Vela JE, Myrick F, Ray AS, Miller MD.

Antivir Ther. 2006;11(3):377-84.

PMID:
16759055
[PubMed - indexed for MEDLINE]
4.

Intracellular pharmacokinetics of tenofovir diphosphate, carbovir triphosphate, and lamivudine triphosphate in patients receiving triple-nucleoside regimens.

Hawkins T, Veikley W, St Claire RL 3rd, Guyer B, Clark N, Kearney BP.

J Acquir Immune Defic Syndr. 2005 Aug 1;39(4):406-11.

PMID:
16010161
[PubMed - indexed for MEDLINE]
5.

Tenofovir disoproxil fumarate-emtricitabine coformulation for once-daily dual NRTI backbone.

Muñoz de Benito RM, Arribas López JR.

Expert Rev Anti Infect Ther. 2006 Aug;4(4):523-35. Review.

PMID:
17009933
[PubMed - indexed for MEDLINE]
7.

Tenofovir diphosphate and emtricitabine triphosphate concentrations in blood cells compared with isolated peripheral blood mononuclear cells: a new measure of antiretroviral adherence?

Adams JL, Sykes C, Menezes P, Prince HM, Patterson KB, Fransen K, Crucitti T, De Baetselier I, Van Damme L, Kashuba AD.

J Acquir Immune Defic Syndr. 2013 Mar 1;62(3):260-6. doi: 10.1097/QAI.0b013e3182794723.

PMID:
23111578
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Determination of nucleoside analog mono-, di-, and tri-phosphates in cellular matrix by solid phase extraction and ultra-sensitive LC-MS/MS detection.

Bushman LR, Kiser JJ, Rower JE, Klein B, Zheng JH, Ray ML, Anderson PL.

J Pharm Biomed Anal. 2011 Sep 10;56(2):390-401. doi: 10.1016/j.jpba.2011.05.039. Epub 2011 Jun 6.

PMID:
21715120
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Liquid chromatography-tandem mass spectrometric determination of tenofovir-diphosphate in human peripheral blood mononuclear cells.

King T, Bushman L, Kiser J, Anderson PL, Ray M, Delahunty T, Fletcher CV.

J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Nov 7;843(2):147-56. Epub 2006 Jul 7.

PMID:
16828350
[PubMed - indexed for MEDLINE]
10.

The simultaneous assay of tenofovir and emtricitabine in plasma using LC/MS/MS and isotopically labeled internal standards.

Delahunty T, Bushman L, Robbins B, Fletcher CV.

J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Jul 1;877(20-21):1907-14. doi: 10.1016/j.jchromb.2009.05.029. Epub 2009 May 21.

PMID:
19493710
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for simultaneous determination of tenofovir and emtricitabine in human plasma and its application to a bioequivalence study.

Gomes NA, Vaidya VV, Pudage A, Joshi SS, Parekh SA.

J Pharm Biomed Anal. 2008 Nov 4;48(3):918-26. doi: 10.1016/j.jpba.2008.07.022. Epub 2008 Aug 5.

PMID:
18783908
[PubMed - indexed for MEDLINE]
12.

Novel direct detection method for quantitative determination of intracellular nucleoside triphosphates using weak anion exchange liquid chromatography/tandem mass spectrometry.

Shi G, Wu JT, Li Y, Geleziunas R, Gallagher K, Emm T, Olah T, Unger S.

Rapid Commun Mass Spectrom. 2002;16(11):1092-9.

PMID:
11992513
[PubMed - indexed for MEDLINE]
13.

In vitro interactions between apricitabine and other deoxycytidine analogues.

Bethell R, De Muys J, Lippens J, Richard A, Hamelin B, Ren C, Collins P.

Antimicrob Agents Chemother. 2007 Aug;51(8):2948-53. Epub 2007 May 21.

PMID:
17517847
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Effect of mobile phase pH and organic content on LC-MS analysis of nucleoside and nucleotide HIV reverse transcriptase inhibitors.

Kuklenyik Z, Martin A, Pau CP, Garcia-Lerma JG, Heneine W, Pirkle JL, Barr JR.

J Chromatogr Sci. 2009 May-Jun;47(5):365-72.

PMID:
19476704
[PubMed - indexed for MEDLINE]
Free Article
15.

Simultaneous measurement of intracellular triphosphate metabolites of zidovudine, lamivudine and abacavir (carbovir) in human peripheral blood mononuclear cells by combined anion exchange solid phase extraction and LC-MS/MS.

Robbins BL, Poston PA, Neal EF, Slaughter C, Rodman JH.

J Chromatogr B Analyt Technol Biomed Life Sci. 2007 May 1;850(1-2):310-7. Epub 2006 Dec 17.

PMID:
17197254
[PubMed - indexed for MEDLINE]
16.

Characterization of emtricitabine related substances by liquid chromatography coupled to an ion trap mass spectrometer.

Pendela M, Mamade DA, Hoogmartens J, Van Schepdael A, Adams E.

Talanta. 2010 Jun 30;82(1):125-8. doi: 10.1016/j.talanta.2010.04.004. Epub 2010 Apr 13.

PMID:
20685446
[PubMed - indexed for MEDLINE]
17.

Measurement of intracellular didanosine and tenofovir phosphorylated metabolites and possible interaction of the two drugs in human immunodeficiency virus-infected patients.

Pruvost A, Negredo E, Benech H, Theodoro F, Puig J, Grau E, García E, Moltó J, Grassi J, Clotet B.

Antimicrob Agents Chemother. 2005 May;49(5):1907-14.

PMID:
15855513
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Quantitation of zidovudine triphosphate concentrations from human peripheral blood mononuclear cells by anion exchange solid phase extraction and liquid chromatography-tandem mass spectroscopy; an indirect quantitation methodology.

King T, Bushman L, Anderson PL, Delahunty T, Ray M, Fletcher CV.

J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Feb 2;831(1-2):248-57. Epub 2006 Jan 10.

PMID:
16412710
[PubMed - indexed for MEDLINE]
19.

Metabolic activation of nucleoside and nucleotide reverse transcriptase inhibitors in dendritic and Langerhans cells.

Balzarini J, Van Herrewege Y, Vanham G.

AIDS. 2002 Nov 8;16(16):2159-63.

PMID:
12409737
[PubMed - indexed for MEDLINE]
20.

Molecular assessment of the potential for renal drug interactions between tenofovir and HIV protease inhibitors.

Cihlar T, Ray AS, Laflamme G, Vela JE, Tong L, Fuller MD, Roy A, Rhodes GR.

Antivir Ther. 2007;12(2):267-72.

PMID:
17503669
[PubMed - indexed for MEDLINE]

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