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Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.

Holt LJ, Tuch BB, Villén J, Johnson AD, Gygi SP, Morgan DO.

Science. 2009 Sep 25;325(5948):1682-6. doi: 10.1126/science.1172867.


Targets of the cyclin-dependent kinase Cdk1.

Ubersax JA, Woodbury EL, Quang PN, Paraz M, Blethrow JD, Shah K, Shokat KM, Morgan DO.

Nature. 2003 Oct 23;425(6960):859-64.


Dynamics of Cdk1 substrate specificity during the cell cycle.

Kõivomägi M, Valk E, Venta R, Iofik A, Lepiku M, Morgan DO, Loog M.

Mol Cell. 2011 Jun 10;42(5):610-23. doi: 10.1016/j.molcel.2011.05.016.


Protein kinases display minimal interpositional dependence on substrate sequence: potential implications for the evolution of signalling networks.

Joughin BA, Liu C, Lauffenburger DA, Hogue CW, Yaffe MB.

Philos Trans R Soc Lond B Biol Sci. 2012 Sep 19;367(1602):2574-83. doi: 10.1098/rstb.2012.0010.


Covalent capture of kinase-specific phosphopeptides reveals Cdk1-cyclin B substrates.

Blethrow JD, Glavy JS, Morgan DO, Shokat KM.

Proc Natl Acad Sci U S A. 2008 Feb 5;105(5):1442-7. doi: 10.1073/pnas.0708966105. Epub 2008 Jan 30.


Multisite phosphorylation networks as signal processors for Cdk1.

Kõivomägi M, Ord M, Iofik A, Valk E, Venta R, Faustova I, Kivi R, Balog ER, Rubin SM, Loog M.

Nat Struct Mol Biol. 2013 Dec;20(12):1415-24. doi: 10.1038/nsmb.2706. Epub 2013 Nov 3.


Differential regulation of CDP/Cux p110 by cyclin A/Cdk2 and cyclin A/Cdk1.

Santaguida M, Nepveu A.

J Biol Chem. 2005 Sep 23;280(38):32712-21. Epub 2005 Aug 3.


Yeast IME2 functions early in meiosis upstream of cell cycle-regulated SBF and MBF targets.

Brush GS, Najor NA, Dombkowski AA, Cukovic D, Sawarynski KE.

PLoS One. 2012;7(2):e31575. doi: 10.1371/journal.pone.0031575. Epub 2012 Feb 29.


Rapid Cdc13 turnover and telomere length homeostasis are controlled by Cdk1-mediated phosphorylation of Cdc13.

Tseng SF, Shen ZJ, Tsai HJ, Lin YH, Teng SC.

Nucleic Acids Res. 2009 Jun;37(11):3602-11. doi: 10.1093/nar/gkp235. Epub 2009 Apr 9.


Identification of Clb2 residues required for Swe1 regulation of Clb2-Cdc28 in Saccharomyces cerevisiae.

Hu F, Gan Y, Aparicio OM.

Genetics. 2008 Jun;179(2):863-74. doi: 10.1534/genetics.108.086611.


The cyclin-dependent kinase Cdk1 directly regulates vacuole inheritance.

Peng Y, Weisman LS.

Dev Cell. 2008 Sep;15(3):478-85. doi: 10.1016/j.devcel.2008.07.007.


Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases.

Hao B, Oehlmann S, Sowa ME, Harper JW, Pavletich NP.

Mol Cell. 2007 Apr 13;26(1):131-43.


Cascades of multisite phosphorylation control Sic1 destruction at the onset of S phase.

Kõivomägi M, Valk E, Venta R, Iofik A, Lepiku M, Balog ER, Rubin SM, Morgan DO, Loog M.

Nature. 2011 Oct 12;480(7375):128-31. doi: 10.1038/nature10560.


Systematic identification of cell cycle-dependent yeast nucleocytoplasmic shuttling proteins by prediction of composite motifs.

Kosugi S, Hasebe M, Tomita M, Yanagawa H.

Proc Natl Acad Sci U S A. 2009 Jun 23;106(25):10171-6. doi: 10.1073/pnas.0900604106. Epub 2009 Jun 11. Erratum in: Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):13142.


Phosphoproteomic analysis of protein kinase C signaling in Saccharomyces cerevisiae reveals Slt2 mitogen-activated protein kinase (MAPK)-dependent phosphorylation of eisosome core components.

Mascaraque V, Hernáez ML, Jiménez-Sánchez M, Hansen R, Gil C, Martín H, Cid VJ, Molina M.

Mol Cell Proteomics. 2013 Mar;12(3):557-74. doi: 10.1074/mcp.M112.020438. Epub 2012 Dec 9.


Cdk1-dependent regulation of the mitotic inhibitor Wee1.

Harvey SL, Charlet A, Haas W, Gygi SP, Kellogg DR.

Cell. 2005 Aug 12;122(3):407-20.


A phosphatase threshold sets the level of Cdk1 activity in early mitosis in budding yeast.

Harvey SL, Enciso G, Dephoure N, Gygi SP, Gunawardena J, Kellogg DR.

Mol Biol Cell. 2011 Oct;22(19):3595-608. doi: 10.1091/mbc.E11-04-0340. Epub 2011 Aug 17.


Cdk1-dependent control of membrane-trafficking dynamics.

McCusker D, Royou A, Velours C, Kellogg D.

Mol Biol Cell. 2012 Sep;23(17):3336-47. doi: 10.1091/mbc.E11-10-0834. Epub 2012 Jul 5.

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