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Items: 1 to 20 of 92

1.

Identification and functional characterization of phosphorylation sites on GTP cyclohydrolase I.

Du J, Wei N, Xu H, Ge Y, Vásquez-Vivar J, Guan T, Oldham KT, Pritchard KA Jr, Shi Y.

Arterioscler Thromb Vasc Biol. 2009 Dec;29(12):2161-8. doi: 10.1161/ATVBAHA.109.194464. Epub 2009 Sep 17.

2.

Quantitative regulation of intracellular endothelial nitric-oxide synthase (eNOS) coupling by both tetrahydrobiopterin-eNOS stoichiometry and biopterin redox status: insights from cells with tet-regulated GTP cyclohydrolase I expression.

Crabtree MJ, Tatham AL, Al-Wakeel Y, Warrick N, Hale AB, Cai S, Channon KM, Alp NJ.

J Biol Chem. 2009 Jan 9;284(2):1136-44. doi: 10.1074/jbc.M805403200. Epub 2008 Nov 14.

3.

[V-1, a catecholamine biosynthesis regulatory protein, enhances GTP cyclohydrolase I gene transcription in a cAMP-responsive element dependent manner].

Yamakuni T, Suzuki T, Inagaki H, Ohizumi Y, Nagatsu T, Ichinose H.

Nihon Yakurigaku Zasshi. 2002 Nov;120(1):82P-84P. Japanese.

PMID:
12491788
4.

cGMP inhibits GTP cyclohydrolase I activity and biosynthesis of tetrahydrobiopterin in human umbilical vein endothelial cells.

Shiraishi H, Kato T, Atsuta K, Sumi-Ichinose C, Ohtsuki M, Itoh M, Hishida H, Tada S, Udagawa Y, Nagatsu T, Hagino Y, Ichinose H, Nomura T.

J Pharmacol Sci. 2003 Nov;93(3):265-71.

5.

Identification of proteins interacting with GTP cyclohydrolase I.

Du J, Xu H, Wei N, Wakim B, Halligan B, Pritchard KA Jr, Shi Y.

Biochem Biophys Res Commun. 2009 Jul 24;385(2):143-7. doi: 10.1016/j.bbrc.2009.05.026. Epub 2009 May 12.

6.

Enhanced expression of GTP cyclohydrolase I in V-1-overexpressing PC12D cells.

Suzuki T, Inagaki H, Yamakuni T, Nagatsu T, Ichinose H.

Biochem Biophys Res Commun. 2002 May 10;293(3):962-8.

PMID:
12051753
7.

Endothelium-specific GTP cyclohydrolase I overexpression attenuates blood pressure progression in salt-sensitive low-renin hypertension.

Du YH, Guan YY, Alp NJ, Channon KM, Chen AF.

Circulation. 2008 Feb 26;117(8):1045-54. doi: 10.1161/CIRCULATIONAHA.107.748236. Epub 2008 Feb 11.

8.
9.

GTP cyclohydrolase regulation: implications for brain development and function.

Ichinose H, Homma D, Sumi-Ichinose C, Nomura T, Kondo K.

Adv Pharmacol. 2013;68:23-35. doi: 10.1016/B978-0-12-411512-5.00003-8. Review.

PMID:
24054139
10.

Cloning, expression, purification, and characterization of Nocardia sp. GTP cyclohydrolase I.

He A, Simpson DR, Daniels L, Rosazza JP.

Protein Expr Purif. 2004 Jun;35(2):171-80.

PMID:
15135390
11.

A new use for a familiar fold: the X-ray crystal structure of GTP-bound GTP cyclohydrolase III from Methanocaldococcus jannaschii reveals a two metal ion catalytic mechanism.

Morrison SD, Roberts SA, Zegeer AM, Montfort WR, Bandarian V.

Biochemistry. 2008 Jan 8;47(1):230-42. Epub 2007 Dec 4.

PMID:
18052207
12.
13.

Regulation of pteridine-requiring enzymes by the cofactor tetrahydrobiopterin.

Nagatsu T, Ichinose H.

Mol Neurobiol. 1999 Feb;19(1):79-96. Review.

PMID:
10321973
14.

Interaction of human GTP cyclohydrolase I with its splice variants.

Pandya MJ, Golderer G, Werner ER, Werner-Felmayer G.

Biochem J. 2006 Nov 15;400(1):75-80.

15.

Down-regulation of GTP cyclohydrolase I and tetrahydrobiopterin by melatonin.

Jang YJ, Hong HN, Lee JD, Hwang O.

Neuroreport. 2000 Nov 9;11(16):3627-30.

PMID:
11095532
16.
17.

Expression of GTP cyclohydrolase I in murine locus ceruleus is enhanced by peripheral administration of lipopolysaccharide.

Kaneko YS, Ikemoto K, Mori K, Nakashima A, Nagatsu I, Ota A.

Brain Res. 2001 Feb 2;890(2):203-10.

PMID:
11164786
18.

GTP cyclohydrolase I/BH4 pathway protects EPCs via suppressing oxidative stress and thrombospondin-1 in salt-sensitive hypertension.

Xie HH, Zhou S, Chen DD, Channon KM, Su DF, Chen AF.

Hypertension. 2010 Dec;56(6):1137-44. doi: 10.1161/HYPERTENSIONAHA.110.160622. Epub 2010 Nov 8.

19.

Immunocytochemical localization of GTP cyclohydrolase I in the brain, adrenal gland, and liver of mice.

Nagatsu I, Ichinose H, Sakai M, Titani K, Suzuki M, Nagatsu T.

J Neural Transm Gen Sect. 1995;102(3):175-188.

PMID:
8788067
20.

Identification of an enhancer region for immune activation in the human GTP cyclohydrolase I gene.

Liang Y, Inagaki H, Hao Q, Sakamoto M, Ohye T, Suzuki T, Ichinose H.

Biochem Biophys Res Commun. 2013 Dec 6;442(1-2):72-8. doi: 10.1016/j.bbrc.2013.11.002. Epub 2013 Nov 9.

PMID:
24220333
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