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Items: 1 to 20 of 99

1.

Mass spectral characterization of organophosphate-labeled, tyrosine-containing peptides: characteristic mass fragments and a new binding motif for organophosphates.

Schopfer LM, Grigoryan H, Li B, Nachon F, Masson P, Lockridge O.

J Chromatogr B Analyt Technol Biomed Life Sci. 2010 May 15;878(17-18):1297-311. doi: 10.1016/j.jchromb.2009.07.026. Epub 2009 Jul 24.

2.

Covalent binding of the organophosphorus agent FP-biotin to tyrosine in eight proteins that have no active site serine.

Grigoryan H, Li B, Anderson EK, Xue W, Nachon F, Lockridge O, Schopfer LM.

Chem Biol Interact. 2009 Aug 14;180(3):492-8. doi: 10.1016/j.cbi.2009.03.018. Epub 2009 Apr 2.

3.

Five tyrosines and two serines in human albumin are labeled by the organophosphorus agent FP-biotin.

Ding SJ, Carr J, Carlson JE, Tong L, Xue W, Li Y, Schopfer LM, Li B, Nachon F, Asojo O, Thompson CM, Hinrichs SH, Masson P, Lockridge O.

Chem Res Toxicol. 2008 Sep;21(9):1787-94. doi: 10.1021/tx800144z. Epub 2008 Aug 16.

4.

Mass spectral characterization of organophosphate-labeled lysine in peptides.

Grigoryan H, Li B, Xue W, Grigoryan M, Schopfer LM, Lockridge O.

Anal Biochem. 2009 Nov 1;394(1):92-100. doi: 10.1016/j.ab.2009.07.008. Epub 2009 Jul 9.

5.

Mass spectrometry identifies multiple organophosphorylated sites on tubulin.

Grigoryan H, Schopfer LM, Peeples ES, Duysen EG, Grigoryan M, Thompson CM, Lockridge O.

Toxicol Appl Pharmacol. 2009 Oct 15;240(2):149-58. doi: 10.1016/j.taap.2009.07.020. Epub 2009 Jul 24.

6.

Tyrosines of human and mouse transferrin covalently labeled by organophosphorus agents: a new motif for binding to proteins that have no active site serine.

Li B, Schopfer LM, Grigoryan H, Thompson CM, Hinrichs SH, Masson P, Lockridge O.

Toxicol Sci. 2009 Jan;107(1):144-55. doi: 10.1093/toxsci/kfn211. Epub 2008 Oct 16.

7.

Mass spectrometry identifies covalent binding of soman, sarin, chlorpyrifos oxon, diisopropyl fluorophosphate, and FP-biotin to tyrosines on tubulin: a potential mechanism of long term toxicity by organophosphorus agents.

Grigoryan H, Schopfer LM, Thompson CM, Terry AV, Masson P, Lockridge O.

Chem Biol Interact. 2008 Sep 25;175(1-3):180-6. doi: 10.1016/j.cbi.2008.04.013. Epub 2008 Apr 22.

8.

Interactions of organophosphates with keratins in the cornified epithelium of human skin.

Verstappen DR, Hulst AG, Fidder A, Vermeulen NP, Noort D.

Chem Biol Interact. 2012 May 30;197(2-3):93-102. doi: 10.1016/j.cbi.2012.04.001. Epub 2012 Apr 13.

PMID:
22521715
9.

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry assay for organophosphorus toxicants bound to human albumin at Tyr411.

Li B, Schopfer LM, Hinrichs SH, Masson P, Lockridge O.

Anal Biochem. 2007 Feb 15;361(2):263-72. Epub 2006 Dec 4.

10.

Review of tyrosine and lysine as new motifs for organophosphate binding to proteins that have no active site serine.

Lockridge O, Schopfer LM.

Chem Biol Interact. 2010 Sep 6;187(1-3):344-8. doi: 10.1016/j.cbi.2010.03.002. Epub 2010 Mar 6. Review.

11.

Characteristic mass spectral fragments of the organophosphorus agent FP-biotin and FP-biotinylated peptides from trypsin and bovine albumin (Tyr410).

Schopfer LM, Champion MM, Tamblyn N, Thompson CM, Lockridge O.

Anal Biochem. 2005 Oct 1;345(1):122-32.

PMID:
16125664
12.

Mice treated with a nontoxic dose of chlorpyrifos oxon have diethoxyphosphotyrosine labeled proteins in blood up to 4 days post exposure, detected by mass spectrometry.

Jiang W, Duysen EG, Lockridge O.

Toxicology. 2012 May 16;295(1-3):15-22. doi: 10.1016/j.tox.2012.03.001. Epub 2012 Mar 8.

PMID:
22406659
13.

Nerve agent analogues that produce authentic soman, sarin, tabun, and cyclohexyl methylphosphonate-modified human butyrylcholinesterase.

Gilley C, MacDonald M, Nachon F, Schopfer LM, Zhang J, Cashman JR, Lockridge O.

Chem Res Toxicol. 2009 Oct;22(10):1680-8. doi: 10.1021/tx900090m.

14.

Albumin, a new biomarker of organophosphorus toxicant exposure, identified by mass spectrometry.

Peeples ES, Schopfer LM, Duysen EG, Spaulding R, Voelker T, Thompson CM, Lockridge O.

Toxicol Sci. 2005 Feb;83(2):303-12. Epub 2004 Nov 3.

15.

Identification of protein ubiquitylation by electrospray ionization tandem mass spectrometric analysis of sulfonated tryptic peptides.

Wang D, Kalume D, Pickart C, Pandey A, Cotter RJ.

Anal Chem. 2006 Jun 1;78(11):3681-7.

PMID:
16737224
16.

The extent and effects of peptide sequence scrambling via formation of macrocyclic B ions in model proteins.

Saminathan IS, Wang XS, Guo Y, Krakovska O, Voisin S, Hopkinson AC, Siu KW.

J Am Soc Mass Spectrom. 2010 Dec;21(12):2085-94. doi: 10.1016/j.jasms.2010.09.001. Epub 2010 Sep 9.

18.
19.

Characterization of metal-labelled peptides by matrix-assisted laser desorption/ionization mass spectrometry and tandem mass spectrometry.

Gregorius B, Schaumlöffel D, Hildebrandt A, Tholey A.

Rapid Commun Mass Spectrom. 2010 Nov 30;24(22):3279-89. doi: 10.1002/rcm.4771.

PMID:
20973002
20.

Capillary electrophoresis tandem mass spectrometry of bromine-containing charged derivatives of peptides.

Ferenc G, Pádár P, Janáky T, Szabó Z, Tóth GK, Kovács L, Kele Z.

J Chromatogr A. 2007 Aug 3;1159(1-2):119-24. Epub 2007 May 5.

PMID:
17517418
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