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Results: 1 to 20 of 96

1.

Mass spectral characterization of organophosphate-labeled, tyrosine-containing peptides: characteristic mass fragments and a new binding motif for organophosphates.

Schopfer LM, Grigoryan H, Li B, Nachon F, Masson P, Lockridge O.

J Chromatogr B Analyt Technol Biomed Life Sci. 2010 May 15;878(17-18):1297-311. doi: 10.1016/j.jchromb.2009.07.026. Epub 2009 Jul 24.

PMID:
19762289
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Covalent binding of the organophosphorus agent FP-biotin to tyrosine in eight proteins that have no active site serine.

Grigoryan H, Li B, Anderson EK, Xue W, Nachon F, Lockridge O, Schopfer LM.

Chem Biol Interact. 2009 Aug 14;180(3):492-8. doi: 10.1016/j.cbi.2009.03.018. Epub 2009 Apr 2.

PMID:
19539807
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Five tyrosines and two serines in human albumin are labeled by the organophosphorus agent FP-biotin.

Ding SJ, Carr J, Carlson JE, Tong L, Xue W, Li Y, Schopfer LM, Li B, Nachon F, Asojo O, Thompson CM, Hinrichs SH, Masson P, Lockridge O.

Chem Res Toxicol. 2008 Sep;21(9):1787-94. doi: 10.1021/tx800144z. Epub 2008 Aug 16.

PMID:
18707141
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Mass spectral characterization of organophosphate-labeled lysine in peptides.

Grigoryan H, Li B, Xue W, Grigoryan M, Schopfer LM, Lockridge O.

Anal Biochem. 2009 Nov 1;394(1):92-100. doi: 10.1016/j.ab.2009.07.008. Epub 2009 Jul 9.

PMID:
19596251
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Mass spectrometry identifies multiple organophosphorylated sites on tubulin.

Grigoryan H, Schopfer LM, Peeples ES, Duysen EG, Grigoryan M, Thompson CM, Lockridge O.

Toxicol Appl Pharmacol. 2009 Oct 15;240(2):149-58. doi: 10.1016/j.taap.2009.07.020. Epub 2009 Jul 24.

PMID:
19632257
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Tyrosines of human and mouse transferrin covalently labeled by organophosphorus agents: a new motif for binding to proteins that have no active site serine.

Li B, Schopfer LM, Grigoryan H, Thompson CM, Hinrichs SH, Masson P, Lockridge O.

Toxicol Sci. 2009 Jan;107(1):144-55. doi: 10.1093/toxsci/kfn211. Epub 2008 Oct 16.

PMID:
18930948
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Mass spectrometry identifies covalent binding of soman, sarin, chlorpyrifos oxon, diisopropyl fluorophosphate, and FP-biotin to tyrosines on tubulin: a potential mechanism of long term toxicity by organophosphorus agents.

Grigoryan H, Schopfer LM, Thompson CM, Terry AV, Masson P, Lockridge O.

Chem Biol Interact. 2008 Sep 25;175(1-3):180-6. doi: 10.1016/j.cbi.2008.04.013. Epub 2008 Apr 22.

PMID:
18502412
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Interactions of organophosphates with keratins in the cornified epithelium of human skin.

Verstappen DR, Hulst AG, Fidder A, Vermeulen NP, Noort D.

Chem Biol Interact. 2012 May 30;197(2-3):93-102. doi: 10.1016/j.cbi.2012.04.001. Epub 2012 Apr 13.

PMID:
22521715
[PubMed - indexed for MEDLINE]
9.

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry assay for organophosphorus toxicants bound to human albumin at Tyr411.

Li B, Schopfer LM, Hinrichs SH, Masson P, Lockridge O.

Anal Biochem. 2007 Feb 15;361(2):263-72. Epub 2006 Dec 4.

PMID:
17188226
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Review of tyrosine and lysine as new motifs for organophosphate binding to proteins that have no active site serine.

Lockridge O, Schopfer LM.

Chem Biol Interact. 2010 Sep 6;187(1-3):344-8. doi: 10.1016/j.cbi.2010.03.002. Epub 2010 Mar 6. Review.

PMID:
20211158
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Characteristic mass spectral fragments of the organophosphorus agent FP-biotin and FP-biotinylated peptides from trypsin and bovine albumin (Tyr410).

Schopfer LM, Champion MM, Tamblyn N, Thompson CM, Lockridge O.

Anal Biochem. 2005 Oct 1;345(1):122-32.

PMID:
16125664
[PubMed - indexed for MEDLINE]
12.

Mice treated with a nontoxic dose of chlorpyrifos oxon have diethoxyphosphotyrosine labeled proteins in blood up to 4 days post exposure, detected by mass spectrometry.

Jiang W, Duysen EG, Lockridge O.

Toxicology. 2012 May 16;295(1-3):15-22. doi: 10.1016/j.tox.2012.03.001. Epub 2012 Mar 8.

PMID:
22406659
[PubMed - indexed for MEDLINE]
13.

Identification of protein ubiquitylation by electrospray ionization tandem mass spectrometric analysis of sulfonated tryptic peptides.

Wang D, Kalume D, Pickart C, Pandey A, Cotter RJ.

Anal Chem. 2006 Jun 1;78(11):3681-7.

PMID:
16737224
[PubMed - indexed for MEDLINE]
14.

Albumin, a new biomarker of organophosphorus toxicant exposure, identified by mass spectrometry.

Peeples ES, Schopfer LM, Duysen EG, Spaulding R, Voelker T, Thompson CM, Lockridge O.

Toxicol Sci. 2005 Feb;83(2):303-12. Epub 2004 Nov 3.

PMID:
15525694
[PubMed - indexed for MEDLINE]
Free Article
15.

The extent and effects of peptide sequence scrambling via formation of macrocyclic B ions in model proteins.

Saminathan IS, Wang XS, Guo Y, Krakovska O, Voisin S, Hopkinson AC, Siu KW.

J Am Soc Mass Spectrom. 2010 Dec;21(12):2085-94. doi: 10.1016/j.jasms.2010.09.001. Epub 2010 Sep 9.

PMID:
20947370
[PubMed - indexed for MEDLINE]
Free Article
17.

Characterization of metal-labelled peptides by matrix-assisted laser desorption/ionization mass spectrometry and tandem mass spectrometry.

Gregorius B, Schaumlöffel D, Hildebrandt A, Tholey A.

Rapid Commun Mass Spectrom. 2010 Nov 30;24(22):3279-89. doi: 10.1002/rcm.4771.

PMID:
20973002
[PubMed - indexed for MEDLINE]
18.

Lysine residues direct the chlorination of tyrosines in YXXK motifs of apolipoprotein A-I when hypochlorous acid oxidizes high density lipoprotein.

Bergt C, Fu X, Huq NP, Kao J, Heinecke JW.

J Biol Chem. 2004 Feb 27;279(9):7856-66. Epub 2003 Dec 3.

PMID:
14660678
[PubMed - indexed for MEDLINE]
Free Article
19.

Capillary electrophoresis tandem mass spectrometry of bromine-containing charged derivatives of peptides.

Ferenc G, Pádár P, Janáky T, Szabó Z, Tóth GK, Kovács L, Kele Z.

J Chromatogr A. 2007 Aug 3;1159(1-2):119-24. Epub 2007 May 5.

PMID:
17517418
[PubMed - indexed for MEDLINE]
20.

PHOS-select iron affinity beads enrich peptides for the detection of organophosphorus adducts on albumin.

Jiang W, Dubrovskii YA, Podolskaya EP, Murashko EA, Babakov V, Nachon F, Masson P, Schopfer LM, Lockridge O.

Chem Res Toxicol. 2013 Dec 16;26(12):1917-25. doi: 10.1021/tx400352h. Epub 2013 Nov 14.

PMID:
24187955
[PubMed - in process]

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