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Results: 1 to 20 of 125

1.

Inhibition of carboxylesterase activity of THP1 monocytes/macrophages and recombinant human carboxylesterase 1 by oxysterols and fatty acids.

Crow JA, Herring KL, Xie S, Borazjani A, Potter PM, Ross MK.

Biochim Biophys Acta. 2010 Jan;1801(1):31-41. doi: 10.1016/j.bbalip.2009.09.002. Epub 2009 Sep 15.

PMID:
19761868
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Inactivation of lipid glyceryl ester metabolism in human THP1 monocytes/macrophages by activated organophosphorus insecticides: role of carboxylesterases 1 and 2.

Xie S, Borazjani A, Hatfield MJ, Edwards CC, Potter PM, Ross MK.

Chem Res Toxicol. 2010 Dec 20;23(12):1890-904. doi: 10.1021/tx1002194.

PMID:
21049984
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Identification of palmitoyl protein thioesterase 1 in human THP1 monocytes and macrophages and characterization of unique biochemical activities for this enzyme.

Wang R, Borazjani A, Matthews AT, Mangum LC, Edelmann MJ, Ross MK.

Biochemistry. 2013 Oct 29;52(43):7559-74. doi: 10.1021/bi401138s. Epub 2013 Oct 18.

PMID:
24083319
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Catabolism of 4-hydroxy-2-trans-nonenal by THP1 monocytes/macrophages and inactivation of carboxylesterases by this lipid electrophile.

Borazjani A, Edelmann MJ, Hardin KL, Herring KL, Allen Crow J, Ross MK.

Chem Biol Interact. 2011 Oct 15;194(1):1-12. doi: 10.1016/j.cbi.2011.08.007. Epub 2011 Aug 22.

PMID:
21878322
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Identification of a novel intracellular cholesteryl ester hydrolase (carboxylesterase 3) in human macrophages: compensatory increase in its expression after carboxylesterase 1 silencing.

Zhao B, Bie J, Wang J, Marqueen SA, Ghosh S.

Am J Physiol Cell Physiol. 2012 Aug 15;303(4):C427-35. doi: 10.1152/ajpcell.00103.2012. Epub 2012 Jun 13.

PMID:
22700792
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Characterization of recombinant human carboxylesterases: fluorescein diacetate as a probe substrate for human carboxylesterase 2.

Wang J, Williams ET, Bourgea J, Wong YN, Patten CJ.

Drug Metab Dispos. 2011 Aug;39(8):1329-33. doi: 10.1124/dmd.111.039628. Epub 2011 May 3.

PMID:
21540359
[PubMed - indexed for MEDLINE]
Free Article
7.

Inhibition of carboxylesterase 1 is associated with cholesteryl ester retention in human THP-1 monocyte/macrophages.

Crow JA, Middleton BL, Borazjani A, Hatfield MJ, Potter PM, Ross MK.

Biochim Biophys Acta. 2008 Oct;1781(10):643-54. doi: 10.1016/j.bbalip.2008.07.005. Epub 2008 Aug 5.

PMID:
18762277
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Inhibition of recombinant human carboxylesterase 1 and 2 and monoacylglycerol lipase by chlorpyrifos oxon, paraoxon and methyl paraoxon.

Crow JA, Bittles V, Herring KL, Borazjani A, Potter PM, Ross MK.

Toxicol Appl Pharmacol. 2012 Jan 1;258(1):145-50. doi: 10.1016/j.taap.2011.10.017. Epub 2011 Nov 4.

PMID:
22100607
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Covalent inhibition of recombinant human carboxylesterase 1 and 2 and monoacylglycerol lipase by the carbamates JZL184 and URB597.

Crow JA, Bittles V, Borazjani A, Potter PM, Ross MK.

Biochem Pharmacol. 2012 Nov 1;84(9):1215-22. doi: 10.1016/j.bcp.2012.08.017. Epub 2012 Aug 27.

PMID:
22943979
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Examination of the carboxylesterase phenotype in human liver.

Ross MK, Borazjani A, Wang R, Crow JA, Xie S.

Arch Biochem Biophys. 2012 Jun 1;522(1):44-56. doi: 10.1016/j.abb.2012.04.010. Epub 2012 Apr 16.

PMID:
22525521
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Role of carboxylesterase 1 and impact of natural genetic variants on the hydrolysis of trandolapril.

Zhu HJ, Appel DI, Johnson JA, Chavin KD, Markowitz JS.

Biochem Pharmacol. 2009 Apr 1;77(7):1266-72. doi: 10.1016/j.bcp.2008.12.017. Epub 2009 Jan 6.

PMID:
19185566
[PubMed - indexed for MEDLINE]
12.

Carboxylesterases 1 and 2 hydrolyze phospho-nonsteroidal anti-inflammatory drugs: relevance to their pharmacological activity.

Wong CC, Cheng KW, Xie G, Zhou D, Zhu CH, Constantinides PP, Rigas B.

J Pharmacol Exp Ther. 2012 Feb;340(2):422-32. doi: 10.1124/jpet.111.188508. Epub 2011 Nov 15.

PMID:
22085648
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Biochemical and molecular analysis of carboxylesterase-mediated hydrolysis of cocaine and heroin.

Hatfield MJ, Tsurkan L, Hyatt JL, Yu X, Edwards CC, Hicks LD, Wadkins RM, Potter PM.

Br J Pharmacol. 2010 Aug;160(8):1916-28. doi: 10.1111/j.1476-5381.2010.00700.x.

PMID:
20649590
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Identification of carboxylesterase-dependent dabigatran etexilate hydrolysis.

Laizure SC, Parker RB, Herring VL, Hu ZY.

Drug Metab Dispos. 2014 Feb;42(2):201-6. doi: 10.1124/dmd.113.054353. Epub 2013 Nov 8.

PMID:
24212379
[PubMed - indexed for MEDLINE]
15.

Conclusive identification of the oxybutynin-hydrolyzing enzyme in human liver.

Sato Y, Miyashita A, Iwatsubo T, Usui T.

Drug Metab Dispos. 2012 May;40(5):902-6. doi: 10.1124/dmd.111.043208. Epub 2012 Jan 31.

PMID:
22293119
[PubMed - indexed for MEDLINE]
Free Article
16.

Carboxylesterase-2 is a highly sensitive target of the antiobesity agent orlistat with profound implications in the activation of anticancer prodrugs.

Xiao D, Shi D, Yang D, Barthel B, Koch TH, Yan B.

Biochem Pharmacol. 2013 Feb 1;85(3):439-47. doi: 10.1016/j.bcp.2012.11.026. Epub 2012 Dec 7.

PMID:
23228697
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

In vitro drug metabolism by human carboxylesterase 1: focus on angiotensin-converting enzyme inhibitors.

Thomsen R, Rasmussen HB, Linnet K; INDICES Consortium.

Drug Metab Dispos. 2014 Jan;42(1):126-33. doi: 10.1124/dmd.113.053512. Epub 2013 Oct 18.

PMID:
24141856
[PubMed - indexed for MEDLINE]
19.

Age- and sex-related expression and activity of carboxylesterase 1 and 2 in mouse and human liver.

Zhu HJ, Appel DI, Jiang Y, Markowitz JS.

Drug Metab Dispos. 2009 Sep;37(9):1819-25. doi: 10.1124/dmd.109.028209. Epub 2009 Jun 1.

PMID:
19487248
[PubMed - indexed for MEDLINE]
Free Article
20.

Opossum carboxylesterases: sequences, phylogeny and evidence for CES gene duplication events predating the marsupial-eutherian common ancestor.

Holmes RS, Chan J, Cox LA, Murphy WJ, VandeBerg JL.

BMC Evol Biol. 2008 Feb 20;8:54. doi: 10.1186/1471-2148-8-54.

PMID:
18289373
[PubMed - indexed for MEDLINE]
Free PMC Article

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