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Items: 1 to 20 of 295

1.

Nicotine activates the chemosensory cation channel TRPA1.

Talavera K, Gees M, Karashima Y, Meseguer VM, Vanoirbeek JA, Damann N, Everaerts W, Benoit M, Janssens A, Vennekens R, Viana F, Nemery B, Nilius B, Voets T.

Nat Neurosci. 2009 Oct;12(10):1293-9. doi: 10.1038/nn.2379. Epub 2009 Sep 13.

PMID:
19749751
2.

Nicotine inhibits voltage-dependent sodium channels and sensitizes vanilloid receptors.

Liu L, Zhu W, Zhang ZS, Yang T, Grant A, Oxford G, Simon SA.

J Neurophysiol. 2004 Apr;91(4):1482-91. Epub 2003 Dec 3.

3.

Enhanced activation of the transient receptor potential channel TRPA1 by ajoene, an allicin derivative.

Yassaka RT, Inagaki H, Fujino T, Nakatani K, Kubo T.

Neurosci Res. 2010 Jan;66(1):99-105. doi: 10.1016/j.neures.2009.09.1712. Epub 2009 Oct 4.

PMID:
19808063
4.

Bimodal action of menthol on the transient receptor potential channel TRPA1.

Karashima Y, Damann N, Prenen J, Talavera K, Segal A, Voets T, Nilius B.

J Neurosci. 2007 Sep 12;27(37):9874-84.

5.

TRPA1-mediated responses in trigeminal sensory neurons: interaction between TRPA1 and TRPV1.

Salas MM, Hargreaves KM, Akopian AN.

Eur J Neurosci. 2009 Apr;29(8):1568-78. doi: 10.1111/j.1460-9568.2009.06702.x.

6.

Transient receptor potential V1 regulates activation and modulation of transient receptor potential A1 by Ca2+.

Patil MJ, Jeske NA, Akopian AN.

Neuroscience. 2010 Dec 29;171(4):1109-19. doi: 10.1016/j.neuroscience.2010.09.031. Epub 2010 Sep 25.

7.

Modulation of the transient receptor potential channel TRPA1 by phosphatidylinositol 4,5-biphosphate manipulators.

Karashima Y, Prenen J, Meseguer V, Owsianik G, Voets T, Nilius B.

Pflugers Arch. 2008 Oct;457(1):77-89. doi: 10.1007/s00424-008-0493-6. Epub 2008 May 7.

PMID:
18461353
8.

Chronic alteration in phosphatidylinositol 4,5-biphosphate levels regulates capsaicin and mustard oil responses.

Patil MJ, Belugin S, Akopian AN.

J Neurosci Res. 2011 Jun;89(6):945-54. doi: 10.1002/jnr.22597. Epub 2011 Feb 17.

9.

More than cool: promiscuous relationships of menthol and other sensory compounds.

Macpherson LJ, Hwang SW, Miyamoto T, Dubin AE, Patapoutian A, Story GM.

Mol Cell Neurosci. 2006 Aug;32(4):335-43. Epub 2006 Jul 7.

PMID:
16829128
10.

Direct action and modulating effect of (+)- and (-)-nicotine on ion channels expressed in trigeminal sensory neurons.

Schreiner BS, Lehmann R, Thiel U, Ziemba PM, Beltrán LR, Sherkheli MA, Jeanbourquin P, Hugi A, Werner M, Gisselmann G, Hatt H.

Eur J Pharmacol. 2014 Apr 5;728:48-58. doi: 10.1016/j.ejphar.2014.01.060. Epub 2014 Feb 7.

PMID:
24512725
11.

Bimodal concentration-response of nicotine involves the nicotinic acetylcholine receptor, transient receptor potential vanilloid type 1, and transient receptor potential ankyrin 1 channels in mouse trachea and sensory neurons.

Kichko TI, Lennerz J, Eberhardt M, Babes RM, Neuhuber W, Kobal G, Reeh PW.

J Pharmacol Exp Ther. 2013 Nov;347(2):529-39. doi: 10.1124/jpet.113.205971. Epub 2013 Aug 7.

12.

Cannabinoids desensitize capsaicin and mustard oil responses in sensory neurons via TRPA1 activation.

Akopian AN, Ruparel NB, Patwardhan A, Hargreaves KM.

J Neurosci. 2008 Jan 30;28(5):1064-75. doi: 10.1523/JNEUROSCI.1565-06.2008.

13.

Transient receptor potential channels in sensory neurons are targets of the antimycotic agent clotrimazole.

Meseguer V, Karashima Y, Talavera K, D'Hoedt D, Donovan-Rodríguez T, Viana F, Nilius B, Voets T.

J Neurosci. 2008 Jan 16;28(3):576-86. doi: 10.1523/JNEUROSCI.4772-07.2008.

14.

Isopentenyl pyrophosphate is a novel antinociceptive substance that inhibits TRPV3 and TRPA1 ion channels.

Bang S, Yoo S, Yang TJ, Cho H, Hwang SW.

Pain. 2011 May;152(5):1156-64. doi: 10.1016/j.pain.2011.01.044. Epub 2011 Feb 24.

PMID:
21353389
15.

TRPM3 is a nociceptor channel involved in the detection of noxious heat.

Vriens J, Owsianik G, Hofmann T, Philipp SE, Stab J, Chen X, Benoit M, Xue F, Janssens A, Kerselaers S, Oberwinkler J, Vennekens R, Gudermann T, Nilius B, Voets T.

Neuron. 2011 May 12;70(3):482-94. doi: 10.1016/j.neuron.2011.02.051.

16.

Differentiation dependent expression of TRPA1 and TRPM8 channels in IMR-32 human neuroblastoma cells.

Louhivuori LM, Bart G, Larsson KP, Louhivuori V, Näsman J, Nordström T, Koivisto AP, Akerman KE.

J Cell Physiol. 2009 Oct;221(1):67-74. doi: 10.1002/jcp.21828.

PMID:
19507192
17.

Primary alcohols activate human TRPA1 channel in a carbon chain length-dependent manner.

Komatsu T, Uchida K, Fujita F, Zhou Y, Tominaga M.

Pflugers Arch. 2012 Apr;463(4):549-59. doi: 10.1007/s00424-011-1069-4. Epub 2012 Jan 6.

PMID:
22222967
18.

Hydroxy-alpha-sanshool activates TRPV1 and TRPA1 in sensory neurons.

Koo JY, Jang Y, Cho H, Lee CH, Jang KH, Chang YH, Shin J, Oh U.

Eur J Neurosci. 2007 Sep;26(5):1139-47.

PMID:
17767493
19.

TRPA1 acts as a cold sensor in vitro and in vivo.

Karashima Y, Talavera K, Everaerts W, Janssens A, Kwan KY, Vennekens R, Nilius B, Voets T.

Proc Natl Acad Sci U S A. 2009 Jan 27;106(4):1273-8. doi: 10.1073/pnas.0808487106. Epub 2009 Jan 14.

20.

Activation of transient receptor potential A1 channels by mustard oil, tetrahydrocannabinol and Ca2+ reveals different functional channel states.

Cavanaugh EJ, Simkin D, Kim D.

Neuroscience. 2008 Jul 17;154(4):1467-76. doi: 10.1016/j.neuroscience.2008.04.048. Epub 2008 May 2.

PMID:
18515013
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