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Results: 1 to 20 of 102

1.

Evidence for a novel mechanism for gene amplification in multiple myeloma: 1q12 pericentromeric heterochromatin mediates breakage-fusion-bridge cycles of a 1q12 approximately 23 amplicon.

Sawyer JR, Tian E, Thomas E, Koller M, Stangeby C, Sammartino G, Goosen L, Swanson C, Binz RL, Barlogie B, Shaughnessy J.

Br J Haematol. 2009 Nov;147(4):484-94. doi: 10.1111/j.1365-2141.2009.07869.x. Epub 2009 Sep 9.

PMID:
19744130
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Novel evidence of a role for chromosome 1 pericentric heterochromatin in the pathogenesis of B-cell lymphoma and multiple myeloma.

Le Baccon P, Leroux D, Dascalescu C, Duley S, Marais D, Esmenjaud E, Sotto JJ, Callanan M.

Genes Chromosomes Cancer. 2001 Nov;32(3):250-64.

PMID:
11579465
[PubMed - indexed for MEDLINE]
3.

Analysis of a breakpoint cluster reveals insight into the mechanism of intrachromosomal amplification in a lymphoid malignancy.

Sinclair PB, Parker H, An Q, Rand V, Ensor H, Harrison CJ, Strefford JC.

Hum Mol Genet. 2011 Jul 1;20(13):2591-602. doi: 10.1093/hmg/ddr159. Epub 2011 Apr 12.

PMID:
21487021
[PubMed - indexed for MEDLINE]
Free Article
4.

Molecular cytogenetic analysis of genomic instability at the 1q12-22 chromosomal site in B-cell non-Hodgkin lymphoma.

Itoyama T, Nanjungud G, Chen W, Dyomin VG, Teruya-Feldstein J, Jhanwar SC, Zelenetz AD, Chaganti RS.

Genes Chromosomes Cancer. 2002 Dec;35(4):318-28.

PMID:
12378526
[PubMed - indexed for MEDLINE]
5.

A role for common fragile site induction in amplification of human oncogenes.

Hellman A, Zlotorynski E, Scherer SW, Cheung J, Vincent JB, Smith DI, Trakhtenbrot L, Kerem B.

Cancer Cell. 2002 Feb;1(1):89-97.

PMID:
12086891
[PubMed - indexed for MEDLINE]
Free Article
6.

Jumping translocations of 1q12 in multiple myeloma: a novel mechanism for deletion of 17p in cytogenetically defined high-risk disease.

Sawyer JR, Tian E, Heuck CJ, Epstein J, Johann DJ, Swanson CM, Lukacs JL, Johnson M, Binz R, Boast A, Sammartino G, Usmani S, Zangari M, Waheed S, van Rhee F, Barlogie B.

Blood. 2014 Apr 17;123(16):2504-12. doi: 10.1182/blood-2013-12-546077. Epub 2014 Feb 4.

PMID:
24497533
[PubMed - indexed for MEDLINE]
7.

Amplification of the pericentromeric region of chromosome 1 in a newly established colon carcinoma cell line.

Neglia M, Bertoni L, Zoli W, Giulotto E.

Cancer Genet Cytogenet. 2003 Apr 15;142(2):99-106.

PMID:
12699884
[PubMed - indexed for MEDLINE]
8.

Hypomethylation of chromosome 1 heterochromatin DNA correlates with q-arm copy gain in human hepatocellular carcinoma.

Wong N, Lam WC, Lai PB, Pang E, Lau WY, Johnson PJ.

Am J Pathol. 2001 Aug;159(2):465-71.

PMID:
11485905
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Molecular cytogenetic characterization of the 11q13 amplicon in head and neck squamous cell carcinoma.

Jin C, Jin Y, Gisselsson D, Wennerberg J, Wah TS, Strömbäck B, Kwong YL, Mertens F.

Cytogenet Genome Res. 2006;115(2):99-106.

PMID:
17065789
[PubMed - indexed for MEDLINE]
10.

Homology-mediated end-capping as a primary step of sister chromatid fusion in the breakage-fusion-bridge cycles.

Marotta M, Chen X, Watanabe T, Faber PW, Diede SJ, Tapscott S, Tubbs R, Kondratova A, Stephens R, Tanaka H.

Nucleic Acids Res. 2013 Nov;41(21):9732-40. doi: 10.1093/nar/gkt762. Epub 2013 Aug 23.

PMID:
23975201
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Monosomy 1p36 breakpoint junctions suggest pre-meiotic breakage-fusion-bridge cycles are involved in generating terminal deletions.

Ballif BC, Yu W, Shaw CA, Kashork CD, Shaffer LG.

Hum Mol Genet. 2003 Sep 1;12(17):2153-65. Epub 2003 Jul 15.

PMID:
12915474
[PubMed - indexed for MEDLINE]
Free Article
12.

Low level of DNA repair in human chromosome 1 heterochromatin.

Surrallés J, Darroudi F, Natarajan AT.

Genes Chromosomes Cancer. 1997 Oct;20(2):173-84.

PMID:
9331568
[PubMed - indexed for MEDLINE]
13.

Genomic instability in multiple myeloma: evidence for jumping segmental duplications of chromosome arm 1q.

Sawyer JR, Tricot G, Lukacs JL, Binz RL, Tian E, Barlogie B, Shaughnessy J Jr.

Genes Chromosomes Cancer. 2005 Jan;42(1):95-106.

PMID:
15472896
[PubMed - indexed for MEDLINE]
14.

Overexpression of PDZK1 within the 1q12-q22 amplicon is likely to be associated with drug-resistance phenotype in multiple myeloma.

Inoue J, Otsuki T, Hirasawa A, Imoto I, Matsuo Y, Shimizu S, Taniwaki M, Inazawa J.

Am J Pathol. 2004 Jul;165(1):71-81.

PMID:
15215163
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

A consistent pattern of RIN1 rearrangements in oral squamous cell carcinoma cell lines supports a breakage-fusion-bridge cycle model for 11q13 amplification.

Shuster MI, Han L, Le Beau MM, Davis E, Sawicki M, Lese CM, Park NH, Colicelli J, Gollin SM.

Genes Chromosomes Cancer. 2000 Jun;28(2):153-63.

PMID:
10825000
[PubMed - indexed for MEDLINE]
16.

Jumping translocations of chromosome 1q in multiple myeloma: evidence for a mechanism involving decondensation of pericentromeric heterochromatin.

Sawyer JR, Tricot G, Mattox S, Jagannath S, Barlogie B.

Blood. 1998 Mar 1;91(5):1732-41.

PMID:
9473240
[PubMed - indexed for MEDLINE]
Free Article
17.

Differences in nuclear positioning of 1q12 pericentric heterochromatin in normal and tumor B lymphocytes with 1q rearrangements.

Barki-Celli L, Lefebvre C, Le Baccon P, Nadeau G, Bonnefoix T, Usson Y, Vourc'h C, Khochbin S, Leroux D, Callanan M.

Genes Chromosomes Cancer. 2005 Aug;43(4):339-49.

PMID:
15846776
[PubMed - indexed for MEDLINE]
18.

The origin of chromosome rearrangements at early stages of AMPD2 gene amplification in Chinese hamster cells.

Toledo F, Buttin G, Debatisse M.

Curr Biol. 1993 May 1;3(5):255-64.

PMID:
15335745
[PubMed]
19.

Amplification of the ABCB1 region accompanied by a short sequence of 200bp from chromosome 2 in lung cancer cells.

Kitada K, Yamasaki T, Aikawa S.

Cancer Genet Cytogenet. 2009 Oct;194(1):4-11. doi: 10.1016/j.cancergencyto.2009.05.002.

PMID:
19737648
[PubMed - indexed for MEDLINE]
20.

Chromosomal organization of amplified chromosome 12 sequences in mesenchymal tumors detected by fluorescence in situ hybridization.

Gisselsson D, Höglund M, Mertens F, Mitelman F, Mandahl N.

Genes Chromosomes Cancer. 1998 Nov;23(3):203-12.

PMID:
9790500
[PubMed - indexed for MEDLINE]

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