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Results: 1 to 20 of 126

1.

Mismatch repair system decreases cell survival by stabilizing the tetraploid G1 arrest in response to SN-38.

Bhonde MR, Hanski ML, Stehr J, Jebautzke B, Peiró-Jordán R, Fechner H, Yokoyama KK, Lin WC, Zeitz M, Hanski C.

Int J Cancer. 2010 Jun 15;126(12):2813-25. doi: 10.1002/ijc.24893.

PMID:
19739070
[PubMed - indexed for MEDLINE]
2.

Cellular effects of CPT-11 on colon carcinoma cells: dependence on p53 and hMLH1 status.

Magrini R, Bhonde MR, Hanski ML, Notter M, Scherübl H, Boland CR, Zeitz M, Hanski C.

Int J Cancer. 2002 Sep 1;101(1):23-31.

PMID:
12209584
[PubMed - indexed for MEDLINE]
3.

Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine-mediated cell death and cell cycle responses.

Meyers M, Wagner MW, Hwang HS, Kinsella TJ, Boothman DA.

Cancer Res. 2001 Jul 1;61(13):5193-201.

PMID:
11431359
[PubMed - indexed for MEDLINE]
Free Article
4.

Phosphorylation of chk1 at serine-345 affected by topoisomerase I poison SN-38.

Hapke G, Yin MB, Wu J, Frank C, Rustum YM.

Int J Oncol. 2002 Nov;21(5):1059-66.

PMID:
12370755
[PubMed - indexed for MEDLINE]
5.

CHK1 and CHK2 are differentially involved in mismatch repair-mediated 6-thioguanine-induced cell cycle checkpoint responses.

Yan T, Desai AB, Jacobberger JW, Sramkoski RM, Loh T, Kinsella TJ.

Mol Cancer Ther. 2004 Sep;3(9):1147-57.

PMID:
15367709
[PubMed - indexed for MEDLINE]
Free Article
6.

CPT-11 (SN-38) chemotherapy may be selectively applicable to biliary tract cancer with low hMLH1 expression.

Sato K, Kitajima Y, Kohya N, Koga Y, Ohtaka K, Miyazaki K.

Anticancer Res. 2007 Mar-Apr;27(2):865-72.

PMID:
17465213
[PubMed - indexed for MEDLINE]
Free Article
7.

DNA mismatch repair (MMR) mediates 6-thioguanine genotoxicity by introducing single-strand breaks to signal a G2-M arrest in MMR-proficient RKO cells.

Yan T, Berry SE, Desai AB, Kinsella TJ.

Clin Cancer Res. 2003 Jun;9(6):2327-34.

PMID:
12796402
[PubMed - indexed for MEDLINE]
Free Article
8.
9.

CDK4 inhibition restores G(1)-S arrest in MYCN-amplified neuroblastoma cells in the context of doxorubicin-induced DNA damage.

Gogolin S, Ehemann V, Becker G, Brueckner LM, Dreidax D, Bannert S, Nolte I, Savelyeva L, Bell E, Westermann F.

Cell Cycle. 2013 Apr 1;12(7):1091-104. doi: 10.4161/cc.24091. Epub 2013 Mar 5.

PMID:
23462184
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Loss of DNA mismatch repair imparts defective cdc2 signaling and G(2) arrest responses without altering survival after ionizing radiation.

Yan T, Schupp JE, Hwang HS, Wagner MW, Berry SE, Strickfaden S, Veigl ML, Sedwick WD, Boothman DA, Kinsella TJ.

Cancer Res. 2001 Nov 15;61(22):8290-7.

PMID:
11719462
[PubMed - indexed for MEDLINE]
Free Article
11.

Role of hMLH1 in sterigmatocystin-induced G₂ phase arrest in human esophageal epithelial Het-1A cells in vitro.

Wang J, Huang S, Xing L, Shen H, Yan X, Wang J, Zhang X.

Toxicol Lett. 2013 Mar 13;217(3):226-34. doi: 10.1016/j.toxlet.2012.12.020. Epub 2013 Jan 4.

PMID:
23296099
[PubMed - indexed for MEDLINE]
12.

Equivalent effect of DNA damage-induced apoptotic cell death or long-term cell cycle arrest on colon carcinoma cell proliferation and tumour growth.

Bhonde MR, Hanski ML, Notter M, Gillissen BF, Daniel PT, Zeitz M, Hanski C.

Oncogene. 2006 Jan 12;25(2):165-75.

PMID:
16170360
[PubMed - indexed for MEDLINE]
13.

DNA damage induced by temozolomide signals to both ATM and ATR: role of the mismatch repair system.

Caporali S, Falcinelli S, Starace G, Russo MT, Bonmassar E, Jiricny J, D'Atri S.

Mol Pharmacol. 2004 Sep;66(3):478-91.

PMID:
15322239
[PubMed - indexed for MEDLINE]
Free Article
14.

The impact of S- and G2-checkpoint response on the fidelity of G1-arrest by cisplatin and its comparison to a non-cross-resistant platinum(IV) analog.

He G, Kuang J, Khokhar AR, Siddik ZH.

Gynecol Oncol. 2011 Aug;122(2):402-9. doi: 10.1016/j.ygyno.2011.04.034. Epub 2011 May 18.

PMID:
21592546
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

DNA damage-induced expression of p53 suppresses mitotic checkpoint kinase hMps1: the lack of this suppression in p53MUT cells contributes to apoptosis.

Bhonde MR, Hanski ML, Budczies J, Cao M, Gillissen B, Moorthy D, Simonetta F, Scherübl H, Truss M, Hagemeier C, Mewes HW, Daniel PT, Zeitz M, Hanski C.

J Biol Chem. 2006 Mar 31;281(13):8675-85. Epub 2006 Jan 30.

PMID:
16446370
[PubMed - indexed for MEDLINE]
Free Article
16.

MSH3 mismatch repair protein regulates sensitivity to cytotoxic drugs and a histone deacetylase inhibitor in human colon carcinoma cells.

Park JM, Huang S, Tougeron D, Sinicrope FA.

PLoS One. 2013 May 28;8(5):e65369. doi: 10.1371/journal.pone.0065369. Print 2013.

PMID:
23724141
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Selenium compounds activate ATM-dependent DNA damage response via the mismatch repair protein hMLH1 in colorectal cancer cells.

Qi Y, Schoene NW, Lartey FM, Cheng WH.

J Biol Chem. 2010 Oct 22;285(43):33010-7. doi: 10.1074/jbc.M110.137406. Epub 2010 Aug 6.

PMID:
20709753
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Effect of H(2)O(2) on cell cycle and survival in DNA mismatch repair-deficient and -proficient cell lines.

Chang DK, Goel A, Ricciardiello L, Lee DH, Chang CL, Carethers JM, Boland CR.

Cancer Lett. 2003 Jun 10;195(2):243-51.

PMID:
12767533
[PubMed - indexed for MEDLINE]
19.

Role of the mismatch repair system and p53 in the clastogenicity and cytotoxicity induced by bleomycin.

Vernole P, Tedeschi B, Tentori L, Levati L, Argentin G, Cicchetti R, Forini O, Graziani G, D'Atri S.

Mutat Res. 2006 Feb 22;594(1-2):63-77. Epub 2005 Sep 1.

PMID:
16139849
[PubMed - indexed for MEDLINE]
20.

Mismatch repair and p53 independently affect sensitivity to N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosourea.

Aquilina G, Ceccotti S, Martinelli S, Soddu S, Crescenzi M, Branch P, Karran P, Bignami M.

Clin Cancer Res. 2000 Feb;6(2):671-80.

PMID:
10690553
[PubMed - indexed for MEDLINE]
Free Article

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