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Results: 1 to 20 of 136

1.

Ror2 receptor requires tyrosine kinase activity to mediate Wnt5A signaling.

Mikels A, Minami Y, Nusse R.

J Biol Chem. 2009 Oct 30;284(44):30167-76. doi: 10.1074/jbc.M109.041715. Epub 2009 Aug 31.

PMID:
19720827
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Purified Wnt5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context.

Mikels AJ, Nusse R.

PLoS Biol. 2006 Apr;4(4):e115. Epub 2006 Apr 4.

PMID:
16602827
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The Wnt5a/Ror2 noncanonical signaling pathway inhibits canonical Wnt signaling in K562 cells.

Yuan Y, Niu CC, Deng G, Li ZQ, Pan J, Zhao C, Yang ZL, Si WK.

Int J Mol Med. 2011 Jan;27(1):63-9. doi: 10.3892/ijmm.2010.560. Epub 2010 Nov 10.

PMID:
21069266
[PubMed - indexed for MEDLINE]
4.

Wnt5a induces homodimerization and activation of Ror2 receptor tyrosine kinase.

Liu Y, Rubin B, Bodine PV, Billiard J.

J Cell Biochem. 2008 Oct 1;105(2):497-502. doi: 10.1002/jcb.21848.

PMID:
18615587
[PubMed - indexed for MEDLINE]
5.

Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis.

Maeda K, Kobayashi Y, Udagawa N, Uehara S, Ishihara A, Mizoguchi T, Kikuchi Y, Takada I, Kato S, Kani S, Nishita M, Marumo K, Martin TJ, Minami Y, Takahashi N.

Nat Med. 2012 Feb 19;18(3):405-12. doi: 10.1038/nm.2653.

PMID:
22344299
[PubMed - indexed for MEDLINE]
6.

Myeloma cells inhibit non-canonical wnt co-receptor ror2 expression in human bone marrow osteoprogenitor cells: effect of wnt5a/ror2 pathway activation on the osteogenic differentiation impairment induced by myeloma cells.

Bolzoni M, Donofrio G, Storti P, Guasco D, Toscani D, Lazzaretti M, Bonomini S, Agnelli L, Capocefalo A, Dalla Palma B, Neri A, Nicolini F, Lisignoli G, Russo F, Colla S, Aversa F, Giuliani N.

Leukemia. 2013 Feb;27(2):451-63. doi: 10.1038/leu.2012.190. Epub 2012 Jul 11.

PMID:
22781592
[PubMed - indexed for MEDLINE]
7.

Ror2/Frizzled complex mediates Wnt5a-induced AP-1 activation by regulating Dishevelled polymerization.

Nishita M, Itsukushima S, Nomachi A, Endo M, Wang Z, Inaba D, Qiao S, Takada S, Kikuchi A, Minami Y.

Mol Cell Biol. 2010 Jul;30(14):3610-9. doi: 10.1128/MCB.00177-10. Epub 2010 May 10.

PMID:
20457807
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Prognostic significance of Ror2 and Wnt5a expression in medulloblastoma.

Lee SE, Lim SD, Kang SY, Suh SB, Suh YL.

Brain Pathol. 2013 Jul;23(4):445-53. doi: 10.1111/bpa.12017. Epub 2013 Jan 25.

PMID:
23278988
[PubMed - indexed for MEDLINE]
9.

The orphan tyrosine kinase receptor, ROR2, mediates Wnt5A signaling in metastatic melanoma.

O'Connell MP, Fiori JL, Xu M, Carter AD, Frank BP, Camilli TC, French AD, Dissanayake SK, Indig FE, Bernier M, Taub DD, Hewitt SM, Weeraratna AT.

Oncogene. 2010 Jan 7;29(1):34-44. doi: 10.1038/onc.2009.305. Epub 2009 Oct 5.

PMID:
19802008
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Dissection of Wnt5a-Ror2 signaling leading to matrix metalloproteinase (MMP-13) expression.

Yamagata K, Li X, Ikegaki S, Oneyama C, Okada M, Nishita M, Minami Y.

J Biol Chem. 2012 Jan 6;287(2):1588-99. doi: 10.1074/jbc.M111.315127. Epub 2011 Nov 28.

PMID:
22128168
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Loss of Wnt5a and Ror2 protein in hepatocellular carcinoma associated with poor prognosis.

Geng M, Cao YC, Chen YJ, Jiang H, Bi LQ, Liu XH.

World J Gastroenterol. 2012 Mar 28;18(12):1328-38. doi: 10.3748/wjg.v18.i12.1328.

PMID:
22493546
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway.

Oishi I, Suzuki H, Onishi N, Takada R, Kani S, Ohkawara B, Koshida I, Suzuki K, Yamada G, Schwabe GC, Mundlos S, Shibuya H, Takada S, Minami Y.

Genes Cells. 2003 Jul;8(7):645-54.

PMID:
12839624
[PubMed - indexed for MEDLINE]
13.

Wnt5a/Ror2-induced upregulation of xPAPC requires xShcA.

Feike AC, Rachor K, Gentzel M, Schambony A.

Biochem Biophys Res Commun. 2010 Oct 1;400(4):500-6. doi: 10.1016/j.bbrc.2010.08.074. Epub 2010 Aug 21.

PMID:
20732301
[PubMed - indexed for MEDLINE]
14.

Negative regulation of Wnt signaling mediated by CK1-phosphorylated Dishevelled via Ror2.

Witte F, Bernatik O, Kirchner K, Masek J, Mahl A, Krejci P, Mundlos S, Schambony A, Bryja V, Stricker S.

FASEB J. 2010 Jul;24(7):2417-26. doi: 10.1096/fj.09-150615. Epub 2010 Mar 9.

PMID:
20215527
[PubMed - indexed for MEDLINE]
Free Article
15.

The orphan receptor tyrosine kinase Ror2 modulates canonical Wnt signaling in osteoblastic cells.

Billiard J, Way DS, Seestaller-Wehr LM, Moran RA, Mangine A, Bodine PV.

Mol Endocrinol. 2005 Jan;19(1):90-101. Epub 2004 Sep 23.

PMID:
15388793
[PubMed - indexed for MEDLINE]
16.

Filopodia formation mediated by receptor tyrosine kinase Ror2 is required for Wnt5a-induced cell migration.

Nishita M, Yoo SK, Nomachi A, Kani S, Sougawa N, Ohta Y, Takada S, Kikuchi A, Minami Y.

J Cell Biol. 2006 Nov 20;175(4):555-62. Epub 2006 Nov 13.

PMID:
17101698
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Epigenetic identification of receptor tyrosine kinase-like orphan receptor 2 as a functional tumor suppressor inhibiting β-catenin and AKT signaling but frequently methylated in common carcinomas.

Li L, Ying J, Tong X, Zhong L, Su X, Xiang T, Shu X, Rong R, Xiong L, Li H, Chan AT, Ambinder RF, Guo Y, Tao Q.

Cell Mol Life Sci. 2014 Jun;71(11):2179-92. doi: 10.1007/s00018-013-1485-z. Epub 2013 Oct 25.

PMID:
24158497
[PubMed - indexed for MEDLINE]
18.

Receptor tyrosine kinase-like orphan receptor 2 (Ror2) expression creates a poised state of Wnt signaling in renal cancer.

Rasmussen NR, Wright TM, Brooks SA, Hacker KE, Debebe Z, Sendor AB, Walker MP, Major MB, Green J, Wahl GM, Rathmell WK.

J Biol Chem. 2013 Sep 6;288(36):26301-10. doi: 10.1074/jbc.M113.466086. Epub 2013 Jul 26.

PMID:
23893409
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Autonomous regulation of osteosarcoma cell invasiveness by Wnt5a/Ror2 signaling.

Enomoto M, Hayakawa S, Itsukushima S, Ren DY, Matsuo M, Tamada K, Oneyama C, Okada M, Takumi T, Nishita M, Minami Y.

Oncogene. 2009 Sep 10;28(36):3197-208. doi: 10.1038/onc.2009.175. Epub 2009 Jun 29.

PMID:
19561643
[PubMed - indexed for MEDLINE]
20.

Wnt5a modulates glycogen synthase kinase 3 to induce phosphorylation of receptor tyrosine kinase Ror2.

Yamamoto H, Yoo SK, Nishita M, Kikuchi A, Minami Y.

Genes Cells. 2007 Nov;12(11):1215-23.

PMID:
17986005
[PubMed - indexed for MEDLINE]

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