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Pattern of normal age-related regional differences in white matter microstructure is modified by vascular risk.

Kennedy KM, Raz N.

Brain Res. 2009 Nov 10;1297:41-56. doi: 10.1016/j.brainres.2009.08.058. Epub 2009 Aug 25.


Quantitative fiber tracking of lateral and interhemispheric white matter systems in normal aging: relations to timed performance.

Sullivan EV, Rohlfing T, Pfefferbaum A.

Neurobiol Aging. 2010 Mar;31(3):464-81. doi: 10.1016/j.neurobiolaging.2008.04.007. Epub 2008 May 20.


Association between white matter microstructure, executive functions, and processing speed in older adults: the impact of vascular health.

Jacobs HI, Leritz EC, Williams VJ, Van Boxtel MP, van der Elst W, Jolles J, Verhey FR, McGlinchey RE, Milberg WP, Salat DH.

Hum Brain Mapp. 2013 Jan;34(1):77-95. doi: 10.1002/hbm.21412. Epub 2011 Sep 23.


Effects of systolic blood pressure on white-matter integrity in young adults in the Framingham Heart Study: a cross-sectional study.

Maillard P, Seshadri S, Beiser A, Himali JJ, Au R, Fletcher E, Carmichael O, Wolf PA, DeCarli C.

Lancet Neurol. 2012 Dec;11(12):1039-47. doi: 10.1016/S1474-4422(12)70241-7. Epub 2012 Nov 2.


Age-related differences in multiple measures of white matter integrity: A diffusion tensor imaging study of healthy aging.

Bennett IJ, Madden DJ, Vaidya CJ, Howard DV, Howard JH Jr.

Hum Brain Mapp. 2010 Mar;31(3):378-90. doi: 10.1002/hbm.20872.


Inter-individual variation in blood pressure is associated with regional white matter integrity in generally healthy older adults.

Salat DH, Williams VJ, Leritz EC, Schnyer DM, Rudolph JL, Lipsitz LA, McGlinchey RE, Milberg WP.

Neuroimage. 2012 Jan 2;59(1):181-92. doi: 10.1016/j.neuroimage.2011.07.033. Epub 2011 Jul 23.


Differential vulnerability of anterior white matter in nondemented aging with minimal acceleration in dementia of the Alzheimer type: evidence from diffusion tensor imaging.

Head D, Buckner RL, Shimony JS, Williams LE, Akbudak E, Conturo TE, McAvoy M, Morris JC, Snyder AZ.

Cereb Cortex. 2004 Apr;14(4):410-23.


Interindividual variation in serum cholesterol is associated with regional white matter tissue integrity in older adults.

Williams VJ, Leritz EC, Shepel J, McGlinchey RE, Milberg WP, Rudolph JL, Lipsitz LA, Salat DH.

Hum Brain Mapp. 2013 Aug;34(8):1826-41. doi: 10.1002/hbm.22030. Epub 2012 Mar 22.


Cigarette smoking is associated with reduced microstructural integrity of cerebral white matter.

Gons RA, van Norden AG, de Laat KF, van Oudheusden LJ, van Uden IW, Zwiers MP, Norris DG, de Leeuw FE.

Brain. 2011 Jul;134(Pt 7):2116-24. doi: 10.1093/brain/awr145.


Associations between T1 white matter lesion volume and regional white matter microstructure in aging.

Leritz EC, Shepel J, Williams VJ, Lipsitz LA, McGlinchey RE, Milberg WP, Salat DH.

Hum Brain Mapp. 2014 Mar;35(3):1085-100. doi: 10.1002/hbm.22236. Epub 2013 Jan 30.


Loss of white matter integrity is associated with gait disorders in cerebral small vessel disease.

de Laat KF, Tuladhar AM, van Norden AG, Norris DG, Zwiers MP, de Leeuw FE.

Brain. 2011 Jan;134(Pt 1):73-83. doi: 10.1093/brain/awq343. Epub 2010 Dec 14.


White matter integrity and cortical metabolic associations in aging and dementia.

Kuczynski B, Targan E, Madison C, Weiner M, Zhang Y, Reed B, Chui HC, Jagust W.

Alzheimers Dement. 2010 Jan;6(1):54-62. doi: 10.1016/j.jalz.2009.04.1228.


Vascular dementia in leukoaraiosis may be a consequence of capillary loss not only in the lesions, but in normal-appearing white matter and cortex as well.

Brown WR, Moody DM, Thore CR, Challa VR, Anstrom JA.

J Neurol Sci. 2007 Jun 15;257(1-2):62-6. Epub 2007 Feb 23.


Multiple indicators of age-related differences in cerebral white matter and the modifying effects of hypertension.

Burgmans S, van Boxtel MP, Gronenschild EH, Vuurman EF, Hofman P, Uylings HB, Jolles J, Raz N.

Neuroimage. 2010 Feb 1;49(3):2083-93. doi: 10.1016/j.neuroimage.2009.10.035. Epub 2009 Oct 19. Erratum in: Neuroimage. 2010 Nov 1;53(2):800.


Life-span changes of the human brain white matter: diffusion tensor imaging (DTI) and volumetry.

Westlye LT, Walhovd KB, Dale AM, Bjørnerud A, Due-Tønnessen P, Engvig A, Grydeland H, Tamnes CK, Ostby Y, Fjell AM.

Cereb Cortex. 2010 Sep;20(9):2055-68. doi: 10.1093/cercor/bhp280. Epub 2009 Dec 23.


Hypertension and cerebral white matter lesions in a prospective cohort study.

de Leeuw FE, de Groot JC, Oudkerk M, Witteman JC, Hofman A, van Gijn J, Breteler MM.

Brain. 2002 Apr;125(Pt 4):765-72.


Longitudinal study of callosal microstructure in the normal adult aging brain using quantitative DTI fiber tracking.

Sullivan EV, Rohlfing T, Pfefferbaum A.

Dev Neuropsychol. 2010;35(3):233-56. doi: 10.1080/87565641003689556. Review.


Testing the white matter retrogenesis hypothesis of cognitive aging.

Brickman AM, Meier IB, Korgaonkar MS, Provenzano FA, Grieve SM, Siedlecki KL, Wasserman BT, Williams LM, Zimmerman ME.

Neurobiol Aging. 2012 Aug;33(8):1699-715. doi: 10.1016/j.neurobiolaging.2011.06.001. Epub 2011 Jul 23.


Vascular and degenerative processes differentially affect regional interhemispheric connections in normal aging, mild cognitive impairment, and Alzheimer disease.

Lee DY, Fletcher E, Martinez O, Zozulya N, Kim J, Tran J, Buonocore M, Carmichael O, DeCarli C.

Stroke. 2010 Aug;41(8):1791-7. doi: 10.1161/STROKEAHA.110.582163. Epub 2010 Jul 1.

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