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Items: 1 to 20 of 118

1.

Extracellular signal-regulated kinase 1/2 activation counteracts morphine tolerance in the periaqueductal gray of the rat.

Macey TA, Bobeck EN, Hegarty DM, Aicher SA, Ingram SL, Morgan MM.

J Pharmacol Exp Ther. 2009 Nov;331(2):412-8. doi: 10.1124/jpet.109.152157. Epub 2009 Aug 14.

2.

Ligand-biased activation of extracellular signal-regulated kinase 1/2 leads to differences in opioid induced antinociception and tolerance.

Bobeck EN, Ingram SL, Hermes SM, Aicher SA, Morgan MM.

Behav Brain Res. 2016 Feb 1;298(Pt B):17-24. doi: 10.1016/j.bbr.2015.10.032. Epub 2015 Oct 20.

PMID:
26497105
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Glutamate modulation of antinociception, but not tolerance, produced by morphine microinjection into the periaqueductal gray of the rat.

Morgan MM, Bobeck EN, Ingram SL.

Brain Res. 2009 Oct 27;1295:59-66. doi: 10.1016/j.brainres.2009.07.100. Epub 2009 Aug 5.

5.

Functionally selective signaling for morphine and fentanyl antinociception and tolerance mediated by the rat periaqueductal gray.

Morgan MM, Reid RA, Saville KA.

PLoS One. 2014 Dec 11;9(12):e114269. doi: 10.1371/journal.pone.0114269. eCollection 2014.

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Chronic inflammatory pain prevents tolerance to the antinociceptive effect of morphine microinjected into the ventrolateral periaqueductal gray of the rat.

Mehalick ML, Ingram SL, Aicher SA, Morgan MM.

J Pain. 2013 Dec;14(12):1601-10. doi: 10.1016/j.jpain.2013.08.003. Epub 2013 Oct 22.

9.

Repeated cannabinoid injections into the rat periaqueductal gray enhance subsequent morphine antinociception.

Wilson AR, Maher L, Morgan MM.

Neuropharmacology. 2008 Dec;55(7):1219-25. doi: 10.1016/j.neuropharm.2008.07.038. Epub 2008 Aug 5.

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Differential development of antinociceptive tolerance to morphine and fentanyl is not linked to efficacy in the ventrolateral periaqueductal gray of the rat.

Bobeck EN, Haseman RA, Hong D, Ingram SL, Morgan MM.

J Pain. 2012 Aug;13(8):799-807. doi: 10.1016/j.jpain.2012.05.005. Epub 2012 Jul 3.

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Antinociceptive tolerance revealed by cumulative intracranial microinjections of morphine into the periaqueductal gray in the rat.

Morgan MM, Fossum EN, Levine CS, Ingram SL.

Pharmacol Biochem Behav. 2006 Sep;85(1):214-9. Epub 2006 Sep 18.

PMID:
16979226
15.

Change in functional selectivity of morphine with the development of antinociceptive tolerance.

Macey TA, Bobeck EN, Suchland KL, Morgan MM, Ingram SL.

Br J Pharmacol. 2015 Jan;172(2):549-61. doi: 10.1111/bph.12703. Epub 2014 Jul 1.

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Tolerance induced by non-opioid analgesic microinjections into rat's periaqueductal gray and nucleus raphe.

Tsiklauri N, Nozadze I, Gurtskaia G, Berishvili V, Abzianidze E, Tsagareli M.

Georgian Med News. 2010 Mar;(180):47-55.

PMID:
20413817
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The periaqueductal gray contributes to bidirectional enhancement of antinociception between morphine and cannabinoids.

Wilson-Poe AR, Pocius E, Herschbach M, Morgan MM.

Pharmacol Biochem Behav. 2013 Jan;103(3):444-9. doi: 10.1016/j.pbb.2012.10.002. Epub 2012 Oct 10.

20.

Morphine mediates a proinflammatory phenotype via μ-opioid receptor-PKCɛ-Akt-ERK1/2 signaling pathway in activated microglial cells.

Merighi S, Gessi S, Varani K, Fazzi D, Stefanelli A, Borea PA.

Biochem Pharmacol. 2013 Aug 15;86(4):487-96. doi: 10.1016/j.bcp.2013.05.027. Epub 2013 Jun 21.

PMID:
23796752
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