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Results: 1 to 20 of 101

1.

Metabolic glycoengineering: sialic acid and beyond.

Du J, Meledeo MA, Wang Z, Khanna HS, Paruchuri VD, Yarema KJ.

Glycobiology. 2009 Dec;19(12):1382-401. doi: 10.1093/glycob/cwp115. Epub 2009 Aug 12. Review.

PMID:
19675091
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Engineering sialic acid synthetic ability into insect cells: identifying metabolic bottlenecks and devising strategies to overcome them.

Viswanathan K, Lawrence S, Hinderlich S, Yarema KJ, Lee YC, Betenbaugh MJ.

Biochemistry. 2003 Dec 30;42(51):15215-25.

PMID:
14690432
[PubMed - indexed for MEDLINE]
3.

Characterization of the metabolic flux and apoptotic effects of O-hydroxyl- and N-acyl-modified N-acetylmannosamine analogs in Jurkat cells.

Kim EJ, Sampathkumar SG, Jones MB, Rhee JK, Baskaran G, Goon S, Yarema KJ.

J Biol Chem. 2004 Apr 30;279(18):18342-52. Epub 2004 Feb 13.

PMID:
14966124
[PubMed - indexed for MEDLINE]
Free Article
4.

Experimental Design Considerations for In Vitro Non-Natural Glycan Display via Metabolic Oligosaccharide Engineering.

Tan E, Almaraz RT, Khanna HS, Du J, Yarema KJ.

Curr Protoc Chem Biol. 2010 Sep 1;2(3):171-94. doi: 10.1002/9780470559277.ch100059.

PMID:
23839968
[PubMed]
5.

Metabolism of vertebrate amino sugars with N-glycolyl groups: incorporation of N-glycolylhexosamines into mammalian glycans by feeding N-glycolylgalactosamine.

Bergfeld AK, Pearce OM, Diaz SL, Lawrence R, Vocadlo DJ, Choudhury B, Esko JD, Varki A.

J Biol Chem. 2012 Aug 17;287(34):28898-916. doi: 10.1074/jbc.M112.363499. Epub 2012 Jun 12.

PMID:
22692203
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Metabolic oligosaccharide engineering with N-Acyl functionalized ManNAc analogs: cytotoxicity, metabolic flux, and glycan-display considerations.

Almaraz RT, Aich U, Khanna HS, Tan E, Bhattacharya R, Shah S, Yarema KJ.

Biotechnol Bioeng. 2012 Apr;109(4):992-1006. doi: 10.1002/bit.24363. Epub 2011 Nov 21.

PMID:
22068462
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Metabolic glycoengineering through the mammalian GalNAc salvage pathway.

Pouilly S, Piller V, Piller F.

FEBS J. 2012 Feb;279(4):586-98. doi: 10.1111/j.1742-4658.2011.08448.x. Epub 2012 Jan 13.

PMID:
22151230
[PubMed - indexed for MEDLINE]
8.

Metabolic glycoengineering of mesenchymal stromal cells with N-propanoylmannosamine.

Natunen S, Lampinen M, Suila H, Ritamo I, Pitkänen V, Nairn AV, Räbinä J, Laitinen S, Moremen KW, Reutter W, Valmu L.

Glycobiology. 2013 Aug;23(8):1004-12. doi: 10.1093/glycob/cwt039. Epub 2013 May 25.

PMID:
23708401
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Sialic acid metabolism and sialyltransferases: natural functions and applications.

Li Y, Chen X.

Appl Microbiol Biotechnol. 2012 May;94(4):887-905. doi: 10.1007/s00253-012-4040-1. Epub 2012 Apr 13. Review.

PMID:
22526796
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Substrate specificity of the sialic acid biosynthetic pathway.

Jacobs CL, Goon S, Yarema KJ, Hinderlich S, Hang HC, Chai DH, Bertozzi CR.

Biochemistry. 2001 Oct 30;40(43):12864-74.

PMID:
11669623
[PubMed - indexed for MEDLINE]
11.

Selective exo-enzymatic labeling of N-glycans on the surface of living cells by recombinant ST6Gal I.

Mbua NE, Li X, Flanagan-Steet HR, Meng L, Aoki K, Moremen KW, Wolfert MA, Steet R, Boons GJ.

Angew Chem Int Ed Engl. 2013 Dec 2;52(49):13012-5. doi: 10.1002/anie.201307095. Epub 2013 Oct 15.

PMID:
24129959
[PubMed - indexed for MEDLINE]
12.

Engineering intracellular CMP-sialic acid metabolism into insect cells and methods to enhance its generation.

Viswanathan K, Narang S, Hinderlich S, Lee YC, Betenbaugh MJ.

Biochemistry. 2005 May 24;44(20):7526-34.

PMID:
15895995
[PubMed - indexed for MEDLINE]
13.

Importance of sialic acid residues illuminated by live animal imaging using phosphorylcholine self-assembled monolayer-coated quantum dots.

Ohyanagi T, Nagahori N, Shimawaki K, Hinou H, Yamashita T, Sasaki A, Jin T, Iwanaga T, Kinjo M, Nishimura S.

J Am Chem Soc. 2011 Aug 17;133(32):12507-17. doi: 10.1021/ja111201c. Epub 2011 Jul 25.

PMID:
21740000
[PubMed - indexed for MEDLINE]
14.

Characterization of the cellular uptake and metabolic conversion of acetylated N-acetylmannosamine (ManNAc) analogues to sialic acids.

Jones MB, Teng H, Rhee JK, Lahar N, Baskaran G, Yarema KJ.

Biotechnol Bioeng. 2004 Feb 20;85(4):394-405.

PMID:
14755557
[PubMed - indexed for MEDLINE]
15.

Cloning and expression of human sialic acid pathway genes to generate CMP-sialic acids in insect cells.

Lawrence SM, Huddleston KA, Tomiya N, Nguyen N, Lee YC, Vann WF, Coleman TA, Betenbaugh MJ.

Glycoconj J. 2001 Mar;18(3):205-13.

PMID:
11602804
[PubMed - indexed for MEDLINE]
16.

GlcNAc 2-epimerase can serve a catabolic role in sialic acid metabolism.

Luchansky SJ, Yarema KJ, Takahashi S, Bertozzi CR.

J Biol Chem. 2003 Mar 7;278(10):8035-42. Epub 2002 Dec 23.

PMID:
12499362
[PubMed - indexed for MEDLINE]
Free Article
17.

Biochemical engineering of the N-acyl side chain of sialic acid: biological implications.

Keppler OT, Horstkorte R, Pawlita M, Schmidt C, Reutter W.

Glycobiology. 2001 Feb;11(2):11R-18R. Review.

PMID:
11287396
[PubMed - indexed for MEDLINE]
Free Article
18.

Tumour suppressor p16(INK4a) - anoikis-favouring decrease in N/O-glycan/cell surface sialylation by down-regulation of enzymes in sialic acid biosynthesis in tandem in a pancreatic carcinoma model.

Amano M, Eriksson H, Manning JC, Detjen KM, André S, Nishimura S, Lehtiö J, Gabius HJ.

FEBS J. 2012 Nov;279(21):4062-80. doi: 10.1111/febs.12001.

PMID:
22943525
[PubMed - indexed for MEDLINE]
19.

Construction of a functional CMP-sialic acid biosynthesis pathway in Arabidopsis.

Castilho A, Pabst M, Leonard R, Veit C, Altmann F, Mach L, Glössl J, Strasser R, Steinkellner H.

Plant Physiol. 2008 May;147(1):331-9. doi: 10.1104/pp.108.117572. Epub 2008 Mar 7.

PMID:
18326787
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Sialic acids attached to O-glycans modulate voltage-gated potassium channel gating.

Schwetz TA, Norring SA, Ednie AR, Bennett ES.

J Biol Chem. 2011 Feb 11;286(6):4123-32. doi: 10.1074/jbc.M110.171322. Epub 2010 Nov 29.

PMID:
21115483
[PubMed - indexed for MEDLINE]
Free PMC Article
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