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Items: 1 to 20 of 537


Small molecule antagonists of Tcf4/beta-catenin complex inhibit the growth of HCC cells in vitro and in vivo.

Wei W, Chua MS, Grepper S, So S.

Int J Cancer. 2010 May 15;126(10):2426-36. doi: 10.1002/ijc.24810.


Blockade of Wnt-1 signaling leads to anti-tumor effects in hepatocellular carcinoma cells.

Wei W, Chua MS, Grepper S, So SK.

Mol Cancer. 2009 Sep 24;8:76. doi: 10.1186/1476-4598-8-76.


Antitumor activity of natural compounds, curcumin and PKF118-310, as Wnt/β-catenin antagonists against human osteosarcoma cells.

Leow PC, Tian Q, Ong ZY, Yang Z, Ee PL.

Invest New Drugs. 2010 Dec;28(6):766-82. doi: 10.1007/s10637-009-9311-z.


Interferon-α2b and transforming growth factor-β1 treatments on HCC cell lines: Are Wnt/β-catenin pathway and Smads signaling connected in hepatocellular carcinoma?

Ceballos MP, Parody JP, Alvarez Mde L, Ingaramo PI, Carnovale CE, Carrillo MC.

Biochem Pharmacol. 2011 Dec 1;82(11):1682-91. doi: 10.1016/j.bcp.2011.08.001. Epub 2011 Aug 6.


Soluble Frizzled-7 receptor inhibits Wnt signaling and sensitizes hepatocellular carcinoma cells towards doxorubicin.

Wei W, Chua MS, Grepper S, So SK.

Mol Cancer. 2011 Feb 11;10:16. doi: 10.1186/1476-4598-10-16.


Aberrant expression and function of TCF4 in the proliferation of hepatocellular carcinoma cell line BEL-7402.

Zhao DH, Hong JJ, Guo SY, Yang RL, Yuan J, Wen CY, Zhou KY, Li CJ.

Cell Res. 2004 Feb;14(1):74-80.


Proliferation and migration mediated by Dkk-1/Wnt/beta-catenin cascade in a model of hepatocellular carcinoma cells.

Qin X, Zhang H, Zhou X, Wang C, Zhang H, Zhang X, Ye L.

Transl Res. 2007 Nov;150(5):281-94. Epub 2007 Jul 18.


Analysis of the Wnt/B-catenin/TCF4 pathway using SAGE, genome-wide microarray and promoter analysis: Identification of BRI3 and HSF2 as novel targets.

Kavak E, Najafov A, Ozturk N, Seker T, Cavusoglu K, Aslan T, Duru AD, Saygili T, Hoxhaj G, Hiz MC, Unal DO, Birgül-Iyison N, Ozturk M, Koman A.

Cell Signal. 2010 Oct;22(10):1523-35. doi: 10.1016/j.cellsig.2010.05.021. Epub 2010 Jun 9.


Cadmium induces Wnt signaling to upregulate proliferation and survival genes in sub-confluent kidney proximal tubule cells.

Chakraborty PK, Lee WK, Molitor M, Wolff NA, Thévenod F.

Mol Cancer. 2010 May 8;9:102. doi: 10.1186/1476-4598-9-102.


[Study on the role of Wnt/beta-catenin signaling transduction pathway in hepatocellular carcinoma cell line HepG2 and L02 cell line].

Wang QM, Jia LQ, Zhou HY, Li YS.

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2007 Oct;23(10):926-8. Chinese.


Krüppel-like factor 8 is a new Wnt/beta-catenin signaling target gene and regulator in hepatocellular carcinoma.

Yang T, Cai SY, Zhang J, Lu JH, Lin C, Zhai J, Wu MC, Shen F.

PLoS One. 2012;7(6):e39668. doi: 10.1371/journal.pone.0039668. Epub 2012 Jun 27.


Tbx3 is a downstream target of the Wnt/beta-catenin pathway and a critical mediator of beta-catenin survival functions in liver cancer.

Renard CA, Labalette C, Armengol C, Cougot D, Wei Y, Cairo S, Pineau P, Neuveut C, de Reyniès A, Dejean A, Perret C, Buendia MA.

Cancer Res. 2007 Feb 1;67(3):901-10.


Wnt/beta-catenin signaling pathway may regulate cell cycle and expression of cyclin A and cyclin E protein in hepatocellular carcinoma cells.

Wang X, Meng X, Sun X, Liu M, Gao S, Zhao J, Pei F, Yu H.

Cell Cycle. 2009 May 15;8(10):1567-70. Epub 2009 May 19.


Indomethacin induces differential expression of beta-catenin, gamma-catenin and T-cell factor target genes in human colorectal cancer cells.

Hawcroft G, D'Amico M, Albanese C, Markham AF, Pestell RG, Hull MA.

Carcinogenesis. 2002 Jan;23(1):107-14.


Preclinical evaluation of destruxin B as a novel Wnt signaling target suppressing proliferation and metastasis of colorectal cancer using non-invasive bioluminescence imaging.

Yeh CT, Rao YK, Ye M, Wu WS, Chang TC, Wang LS, Wu CH, Wu AT, Tzeng YM.

Toxicol Appl Pharmacol. 2012 May 15;261(1):31-41. doi: 10.1016/j.taap.2012.03.007. Epub 2012 Mar 23.


Small-molecule inhibitors of phosphatidylinositol 3-kinase/Akt signaling inhibit Wnt/beta-catenin pathway cross-talk and suppress medulloblastoma growth.

Baryawno N, Sveinbjörnsson B, Eksborg S, Chen CS, Kogner P, Johnsen JI.

Cancer Res. 2010 Jan 1;70(1):266-76. doi: 10.1158/0008-5472.CAN-09-0578. Epub 2009 Dec 22. Erratum in: Cancer Res. 2010 Mar 1;70(5):2138-9.


EZH2-mediated concordant repression of Wnt antagonists promotes β-catenin-dependent hepatocarcinogenesis.

Cheng AS, Lau SS, Chen Y, Kondo Y, Li MS, Feng H, Ching AK, Cheung KF, Wong HK, Tong JH, Jin H, Choy KW, Yu J, To KF, Wong N, Huang TH, Sung JJ.

Cancer Res. 2011 Jun 1;71(11):4028-39. doi: 10.1158/0008-5472.CAN-10-3342. Epub 2011 Apr 21.


ITF2 prevents activation of the β-catenin-TCF4 complex in colon cancer cells and levels decrease with tumor progression.

Shin HW, Choi H, So D, Kim YI, Cho K, Chung HJ, Lee KH, Chun YS, Cho CH, Kang GH, Kim WH, Park JW.

Gastroenterology. 2014 Aug;147(2):430-442.e8. doi: 10.1053/j.gastro.2014.04.047. Epub 2014 May 15.

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