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Results: 1 to 20 of 103

1.

Identification of enoxacin as an inhibitor of osteoclast formation and bone resorption by structure-based virtual screening.

Ostrov DA, Magis AT, Wronski TJ, Chan EK, Toro EJ, Donatelli RE, Sajek K, Haroun IN, Nagib MI, Piedrahita A, Harris A, Holliday LS.

J Med Chem. 2009 Aug 27;52(16):5144-51. doi: 10.1021/jm900277z.

PMID:
19630402
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Rational identification of enoxacin as a novel V-ATPase-directed osteoclast inhibitor.

Toro EJ, Ostrov DA, Wronski TJ, Holliday LS.

Curr Protein Pept Sci. 2012 Mar;13(2):180-91. Review.

PMID:
22044158
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Enoxacin directly inhibits osteoclastogenesis without inducing apoptosis.

Toro EJ, Zuo J, Ostrov DA, Catalfamo D, Bradaschia-Correa V, Arana-Chavez V, Caridad AR, Neubert JK, Wronski TJ, Wallet SM, Holliday LS.

J Biol Chem. 2012 May 18;287(21):17894-904. doi: 10.1074/jbc.M111.280511. Epub 2012 Apr 2.

PMID:
22474295
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Bis-enoxacin inhibits bone resorption and orthodontic tooth movement.

Toro EJ, Zuo J, Guiterrez A, La Rosa RL, Gawron AJ, Bradaschia-Correa V, Arana-Chavez V, Dolce C, Rivera MF, Kesavalu L, Bhattacharyya I, Neubert JK, Holliday LS.

J Dent Res. 2013 Oct;92(10):925-31. doi: 10.1177/0022034513501876. Epub 2013 Aug 19.

PMID:
23958763
[PubMed - indexed for MEDLINE]
5.

Luteolin inhibition of V-ATPase a3-d2 interaction decreases osteoclast resorptive activity.

Crasto GJ, Kartner N, Yao Y, Li K, Bullock L, Datti A, Manolson MF.

J Cell Biochem. 2013 Apr;114(4):929-41. doi: 10.1002/jcb.24434.

PMID:
23129004
[PubMed - indexed for MEDLINE]
6.

Nicotine affects bone resorption and suppresses the expression of cathepsin K, MMP-9 and vacuolar-type H(+)-ATPase d2 and actin organization in osteoclasts.

Tanaka H, Tanabe N, Kawato T, Nakai K, Kariya T, Matsumoto S, Zhao N, Motohashi M, Maeno M.

PLoS One. 2013;8(3):e59402. doi: 10.1371/journal.pone.0059402. Epub 2013 Mar 15.

PMID:
23555029
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Diphyllin, a novel and naturally potent V-ATPase inhibitor, abrogates acidification of the osteoclastic resorption lacunae and bone resorption.

Sørensen MG, Henriksen K, Neutzsky-Wulff AV, Dziegiel MH, Karsdal MA.

J Bone Miner Res. 2007 Oct;22(10):1640-8.

PMID:
17576165
[PubMed - indexed for MEDLINE]
8.

Inhibition of osteoclast bone resorption by disrupting vacuolar H+-ATPase a3-B2 subunit interaction.

Kartner N, Yao Y, Li K, Crasto GJ, Datti A, Manolson MF.

J Biol Chem. 2010 Nov 26;285(48):37476-90. doi: 10.1074/jbc.M110.123281. Epub 2010 Sep 13.

PMID:
20837476
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Interaction between vacuolar H(+)-ATPase and microfilaments during osteoclast activation.

Lee BS, Gluck SL, Holliday LS.

J Biol Chem. 1999 Oct 8;274(41):29164-71.

PMID:
10506172
[PubMed - indexed for MEDLINE]
Free Article
10.

Bone resorption inhibitor alendronate normalizes the reduced bone thickness of TRPV5(-/-) mice.

Nijenhuis T, van der Eerden BC, Hoenderop JG, Weinans H, van Leeuwen JP, Bindels RJ.

J Bone Miner Res. 2008 Nov;23(11):1815-24. doi: 10.1359/jbmr.080613.

PMID:
18597625
[PubMed - indexed for MEDLINE]
11.

Specific biological functions of vacuolar-type H(+)-ATPase and lysosomal cysteine proteinase, cathepsin K, in osteoclasts.

Sahara T, Itoh K, Debari K, Sasaki T.

Anat Rec A Discov Mol Cell Evol Biol. 2003 Feb;270(2):152-61.

PMID:
12524690
[PubMed - indexed for MEDLINE]
Free Article
12.

V-ATPase subunit ATP6AP1 (Ac45) regulates osteoclast differentiation, extracellular acidification, lysosomal trafficking, and protease exocytosis in osteoclast-mediated bone resorption.

Yang DQ, Feng S, Chen W, Zhao H, Paulson C, Li YP.

J Bone Miner Res. 2012 Aug;27(8):1695-707. doi: 10.1002/jbmr.1623.

PMID:
22467241
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Quercetin suppresses bone resorption by inhibiting the differentiation and activation of osteoclasts.

Woo JT, Nakagawa H, Notoya M, Yonezawa T, Udagawa N, Lee IS, Ohnishi M, Hagiwara H, Nagai K.

Biol Pharm Bull. 2004 Apr;27(4):504-9.

PMID:
15056855
[PubMed - indexed for MEDLINE]
Free Article
14.

Chloroform extract of deer antler inhibits osteoclast differentiation and bone resorption.

Li YJ, Kim TH, Kwak HB, Lee ZH, Lee SY, Jhon GJ.

J Ethnopharmacol. 2007 Sep 5;113(2):191-8. Epub 2007 May 16.

PMID:
17646068
[PubMed - indexed for MEDLINE]
15.

Urocortin is a novel regulator of osteoclast differentiation and function through inhibition of a canonical transient receptor potential 1-like cation channel.

Combs CE, Fuller K, Kumar H, Albert AP, Pirianov G, McCormick J, Locke IC, Chambers TJ, Lawrence KM.

J Endocrinol. 2012 Feb;212(2):187-97. doi: 10.1530/JOE-11-0254. Epub 2011 Nov 14.

PMID:
22083217
[PubMed - indexed for MEDLINE]
Free Article
16.

Calcitonin responsiveness and receptor expression in porcine and murine osteoclasts: a comparative study.

Galvin RJ, Bryan P, Venugopalan M, Smith DP, Thomas JE.

Bone. 1998 Sep;23(3):233-40.

PMID:
9737345
[PubMed - indexed for MEDLINE]
17.

Proteomic identification of the TRAF6 regulation of vacuolar ATPase for osteoclast function.

Ryu J, Kim H, Lee SK, Chang EJ, Kim HJ, Kim HH.

Proteomics. 2005 Nov;5(16):4152-60.

PMID:
16196101
[PubMed - indexed for MEDLINE]
18.

Atp6v0d2 is an essential component of the osteoclast-specific proton pump that mediates extracellular acidification in bone resorption.

Wu H, Xu G, Li YP.

J Bone Miner Res. 2009 May;24(5):871-85. doi: 10.1359/jbmr.081239.

PMID:
19113919
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Coordination of microtubules and the actin cytoskeleton is important in osteoclast function, but calcitonin disrupts sealing zones without affecting microtubule networks.

Okumura S, Mizoguchi T, Sato N, Yamaki M, Kobayashi Y, Yamauchi H, Ozawa H, Udagawa N, Takahashi N.

Bone. 2006 Oct;39(4):684-93. Epub 2006 Jun 13.

PMID:
16774853
[PubMed - indexed for MEDLINE]
20.

Vacuolar H+-ATPase binding to microfilaments: regulation in response to phosphatidylinositol 3-kinase activity and detailed characterization of the actin-binding site in subunit B.

Chen SH, Bubb MR, Yarmola EG, Zuo J, Jiang J, Lee BS, Lu M, Gluck SL, Hurst IR, Holliday LS.

J Biol Chem. 2004 Feb 27;279(9):7988-98. Epub 2003 Dec 8.

PMID:
14662773
[PubMed - indexed for MEDLINE]
Free Article

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