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Results: 1 to 20 of 127

1.

Identification of genes conferring resistance to 5-fluorouracil.

Yoo BK, Gredler R, Vozhilla N, Su ZZ, Chen D, Forcier T, Shah K, Saxena U, Hansen U, Fisher PB, Sarkar D.

Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12938-43. doi: 10.1073/pnas.0901451106. Epub 2009 Jul 21.

PMID:
19622726
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The monoclonal antibody CH12 augments 5-fluorouracil-induced growth suppression of hepatocellular carcinoma xenografts expressing epidermal growth factor receptor variant III.

Jiang H, Dong Q, Luo X, Shi B, Wang H, Gao H, Kong J, Zhang J, Li Z.

Cancer Lett. 2014 Jan 1;342(1):113-20. doi: 10.1016/j.canlet.2013.08.038. Epub 2013 Sep 2.

PMID:
24007863
[PubMed - indexed for MEDLINE]
3.

Characterization and resistance mechanisms of a 5-fluorouracil- resistant hepatocellular carcinoma cell line.

Gu W, Fang FF, Li B, Cheng BB, Ling CQ.

Asian Pac J Cancer Prev. 2012;13(9):4807-14.

PMID:
23167424
[PubMed - indexed for MEDLINE]
Free Article
4.

Astrocyte elevated gene-1 promotes hepatocarcinogenesis: novel insights from a mouse model.

Srivastava J, Siddiq A, Emdad L, Santhekadur PK, Chen D, Gredler R, Shen XN, Robertson CL, Dumur CI, Hylemon PB, Mukhopadhyay ND, Bhere D, Shah K, Ahmad R, Giashuddin S, Stafflinger J, Subler MA, Windle JJ, Fisher PB, Sarkar D.

Hepatology. 2012 Nov;56(5):1782-91. doi: 10.1002/hep.25868.

PMID:
22689379
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Correlation between chemosensitivity and mRNA expression level of 5-fluorouracil-related metabolic enzymes during liver metastasis of colorectal cancer.

Okumura K, Shiomi H, Mekata E, Kaizuka M, Endo Y, Kurumi Y, Tani T.

Oncol Rep. 2006 Apr;15(4):875-82.

PMID:
16525674
[PubMed - indexed for MEDLINE]
6.

Predicting 5-fluorouracil chemosensitivity of liver metastases from colorectal cancer using primary tumor specimens: three-gene expression model predicts clinical response.

Matsuyama R, Togo S, Shimizu D, Momiyama N, Ishikawa T, Ichikawa Y, Endo I, Kunisaki C, Suzuki H, Hayasizaki Y, Shimada H.

Int J Cancer. 2006 Jul 15;119(2):406-13.

PMID:
16477629
[PubMed - indexed for MEDLINE]
7.

Dihydropyrimidine dehydrogenase but not thymidylate synthase expression is associated with resistance to 5-fluorouracil in colorectal cancer.

Nita ME, Tominaga O, Nagawa H, Tsuruo T, Muto T.

Hepatogastroenterology. 1998 Nov-Dec;45(24):2117-22.

PMID:
9951876
[PubMed - indexed for MEDLINE]
8.

TIP30 inhibits growth of HCC cell lines and inhibits HCC xenografts in mice in combination with 5-FU.

Zhao J, Zhang X, Shi M, Xu H, Jin J, Ni H, Yang S, Dai J, Wu M, Guo Y.

Hepatology. 2006 Jul;44(1):205-15.

PMID:
16799960
[PubMed - indexed for MEDLINE]
9.

Consensus interferon enhances the anti-proliferative effect of 5-fluorouracil on human hepatoma cells via downregulation of dihydropyrimidine dehydrogenase expression.

Dou J, Iwashita Y, Sasaki A, Kai S, Hirano S, Ohta M, Kitano S.

Liver Int. 2005 Feb;25(1):148-52.

PMID:
15698412
[PubMed - indexed for MEDLINE]
10.

Sorafenib enhances the chemotherapeutic efficacy of S-1 against hepatocellular carcinoma through downregulation of transcription factor E2F-1.

Zhai JM, Yin XY, Lai YR, Hou X, Cai JP, Hao XY, Liang LJ, Zhang LJ.

Cancer Chemother Pharmacol. 2013 May;71(5):1255-64. doi: 10.1007/s00280-013-2120-2. Epub 2013 Feb 23.

PMID:
23435877
[PubMed - indexed for MEDLINE]
11.

MicroRNA-375 targets AEG-1 in hepatocellular carcinoma and suppresses liver cancer cell growth in vitro and in vivo.

He XX, Chang Y, Meng FY, Wang MY, Xie QH, Tang F, Li PY, Song YH, Lin JS.

Oncogene. 2012 Jul 12;31(28):3357-69. doi: 10.1038/onc.2011.500. Epub 2011 Nov 7.

PMID:
22056881
[PubMed - indexed for MEDLINE]
12.

Molecular mechanism of chemoresistance by astrocyte elevated gene-1.

Yoo BK, Chen D, Su ZZ, Gredler R, Yoo J, Shah K, Fisher PB, Sarkar D.

Cancer Res. 2010 Apr 15;70(8):3249-58. doi: 10.1158/0008-5472.CAN-09-4009. Epub 2010 Apr 13.

PMID:
20388796
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

DNA methylation-regulated miR-193a-3p dictates resistance of hepatocellular carcinoma to 5-fluorouracil via repression of SRSF2 expression.

Ma K, He Y, Zhang H, Fei Q, Niu D, Wang D, Ding X, Xu H, Chen X, Zhu J.

J Biol Chem. 2012 Feb 17;287(8):5639-49. doi: 10.1074/jbc.M111.291229. Epub 2011 Nov 23.

PMID:
22117060
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Transcription factor Late SV40 Factor (LSF) functions as an oncogene in hepatocellular carcinoma.

Yoo BK, Emdad L, Gredler R, Fuller C, Dumur CI, Jones KH, Jackson-Cook C, Su ZZ, Chen D, Saxena UH, Hansen U, Fisher PB, Sarkar D.

Proc Natl Acad Sci U S A. 2010 May 4;107(18):8357-62. doi: 10.1073/pnas.1000374107. Epub 2010 Apr 19.

PMID:
20404171
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Alteration of dihydropyrimidine dehydrogenase expression by IFN-alpha affects the antiproliferative effects of 5-fluorouracil in human hepatocellular carcinoma cells.

Oie S, Ono M, Fukushima H, Hosoi F, Yano H, Maruyama Y, Kojiro M, Terada T, Hirano K, Kuwano M, Yamada Y.

Mol Cancer Ther. 2007 Aug;6(8):2310-8.

PMID:
17699726
[PubMed - indexed for MEDLINE]
Free Article
16.

Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase.

Banerjee D, Mayer-Kuckuk P, Capiaux G, Budak-Alpdogan T, Gorlick R, Bertino JR.

Biochim Biophys Acta. 2002 Jul 18;1587(2-3):164-73. Review.

PMID:
12084458
[PubMed - indexed for MEDLINE]
17.

Opsin3 sensitizes hepatocellular carcinoma cells to 5-fluorouracil treatment by regulating the apoptotic pathway.

Jiao J, Hong S, Zhang J, Ma L, Sun Y, Zhang D, Shen B, Zhu C.

Cancer Lett. 2012 Jul 1;320(1):96-103. doi: 10.1016/j.canlet.2012.01.035. Epub 2012 Feb 4.

PMID:
22313545
[PubMed - indexed for MEDLINE]
18.

Establishment and characterization of two 5-fluorouracil-resistant hepatocellular carcinoma cell lines.

Uchibori K, Kasamatsu A, Sunaga M, Yokota S, Sakurada T, Kobayashi E, Yoshikawa M, Uzawa K, Ueda S, Tanzawa H, Sato N.

Int J Oncol. 2012 Apr;40(4):1005-10. doi: 10.3892/ijo.2011.1300. Epub 2011 Dec 15.

PMID:
22179686
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

AEG-1/MTDH/LYRIC in liver cancer.

Sarkar D.

Adv Cancer Res. 2013;120:193-221. doi: 10.1016/B978-0-12-401676-7.00007-3. Review.

PMID:
23889992
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Synergistic efficacy of 3n-butyrate and 5-fluorouracil in human colorectal cancer xenografts via modulation of DNA synthesis.

Bras-Gonçalves RA, Pocard M, Formento JL, Poirson-Bichat F, De Pinieux G, Pandrea I, Arvelo F, Ronco G, Villa P, Coquelle A, Milano G, Lesuffleur T, Dutrillaux B, Poupon MF.

Gastroenterology. 2001 Mar;120(4):874-88.

PMID:
11231942
[PubMed - indexed for MEDLINE]

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