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Results: 1 to 20 of 212

1.

Analysis of synthetic lethality reveals genetic interactions between the GTPase Snu114p and snRNAs in the catalytic core of the Saccharomyces cerevisiae spliceosome.

Frazer LN, Lovell SC, O'Keefe RT.

Genetics. 2009 Oct;183(2):497-515-1SI-4SI. doi: 10.1534/genetics.109.107243. Epub 2009 Jul 20.

PMID:
19620389
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Mutagenesis suggests several roles of Snu114p in pre-mRNA splicing.

Bartels C, Urlaub H, Luhrmann R, Fabrizio P.

J Biol Chem. 2003 Jul 25;278(30):28324-34. Epub 2003 May 7.

PMID:
12736260
[PubMed - indexed for MEDLINE]
Free Article
3.

The ribosomal translocase homologue Snu114p is involved in unwinding U4/U6 RNA during activation of the spliceosome.

Bartels C, Klatt C, L├╝hrmann R, Fabrizio P.

EMBO Rep. 2002 Sep;3(9):875-80. Epub 2002 Aug 16.

PMID:
12189173
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The EF-G-like GTPase Snu114p regulates spliceosome dynamics mediated by Brr2p, a DExD/H box ATPase.

Small EC, Leggett SR, Winans AA, Staley JP.

Mol Cell. 2006 Aug 4;23(3):389-99.

PMID:
16885028
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Assembly of Snu114 into U5 snRNP requires Prp8 and a functional GTPase domain.

Brenner TJ, Guthrie C.

RNA. 2006 May;12(5):862-71. Epub 2006 Mar 15.

PMID:
16540695
[PubMed - indexed for MEDLINE]
Free PMC Article
6.
8.

Mutations in the U5 snRNA result in altered splicing of subsets of pre-mRNAs and reduced stability of Prp8.

Kershaw CJ, Barrass JD, Beggs JD, O'Keefe RT.

RNA. 2009 Jul;15(7):1292-304. doi: 10.1261/rna.1347409. Epub 2009 May 15.

PMID:
19447917
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Genetic analysis reveals a role for the C terminus of the Saccharomyces cerevisiae GTPase Snu114 during spliceosome activation.

Brenner TJ, Guthrie C.

Genetics. 2005 Jul;170(3):1063-80. Epub 2005 May 23.

PMID:
15911574
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

The splicing factor Prp17 interacts with the U2, U5 and U6 snRNPs and associates with the spliceosome pre- and post-catalysis.

Sapra AK, Khandelia P, Vijayraghavan U.

Biochem J. 2008 Dec 15;416(3):365-74. doi: 10.1042/BJ20081195.

PMID:
18691155
[PubMed - indexed for MEDLINE]
Free Article
11.

The RNA binding protein Cwc2 interacts directly with the U6 snRNA to link the nineteen complex to the spliceosome during pre-mRNA splicing.

McGrail JC, Krause A, O'Keefe RT.

Nucleic Acids Res. 2009 Jul;37(13):4205-17. doi: 10.1093/nar/gkp341. Epub 2009 May 12.

PMID:
19435883
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The Prp19-associated complex is required for specifying interactions of U5 and U6 with pre-mRNA during spliceosome activation.

Chan SP, Cheng SC.

J Biol Chem. 2005 Sep 2;280(35):31190-9. Epub 2005 Jun 30.

PMID:
15994330
[PubMed - indexed for MEDLINE]
Free Article
13.

Randomization-selection analysis of snRNAs in vivo: evidence for a tertiary interaction in the spliceosome.

Madhani HD, Guthrie C.

Genes Dev. 1994 May 1;8(9):1071-86.

PMID:
7926788
[PubMed - indexed for MEDLINE]
Free Article
14.
15.

Distinct domains of splicing factor Prp8 mediate different aspects of spliceosome activation.

Kuhn AN, Reichl EM, Brow DA.

Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9145-9. Epub 2002 Jun 26.

PMID:
12087126
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Protein-RNA interactions in the U5 snRNP of Saccharomyces cerevisiae.

Dix I, Russell CS, O'Keefe RT, Newman AJ, Beggs JD.

RNA. 1998 Oct;4(10):1239-50. Corrected and republished in: RNA 1998 Dec;4(12):1675-86.

PMID:
9769098
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The conserved central domain of yeast U6 snRNA: importance of U2-U6 helix Ia in spliceosome assembly.

Ryan DE, Abelson J.

RNA. 2002 Aug;8(8):997-1010.

PMID:
12212854
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

A novel base-pairing interaction between U2 and U6 snRNAs suggests a mechanism for the catalytic activation of the spliceosome.

Madhani HD, Guthrie C.

Cell. 1992 Nov 27;71(5):803-17.

PMID:
1423631
[PubMed - indexed for MEDLINE]
19.

The U5 snRNA internal loop 1 is a platform for Brr2, Snu114 and Prp8 protein binding during U5 snRNP assembly.

Nancollis V, Ruckshanthi JP, Frazer LN, O'Keefe RT.

J Cell Biochem. 2013 Dec;114(12):2770-84. doi: 10.1002/jcb.24625.

PMID:
23857713
[PubMed - indexed for MEDLINE]
Free PMC Article
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