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Items: 1 to 20 of 103

1.

The Seattle Structural Genomics Center for Infectious Disease (SSGCID).

Myler PJ, Stacy R, Stewart L, Staker BL, Van Voorhis WC, Varani G, Buchko GW.

Infect Disord Drug Targets. 2009 Nov;9(5):493-506. Review.

2.

Structural genomics of infectious disease drug targets: the SSGCID.

Stacy R, Begley DW, Phan I, Staker BL, Van Voorhis WC, Varani G, Buchko GW, Stewart LJ, Myler PJ.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Sep 1;67(Pt 9):979-84. doi: 10.1107/S1744309111029204. Epub 2011 Aug 13.

3.

Structural genomics and drug discovery for infectious diseases.

Anderson WF.

Infect Disord Drug Targets. 2009 Nov;9(5):507-17. Review.

4.

Fragment screening of infectious disease targets in a structural genomics environment.

Begley DW, Davies DR, Hartley RC, Edwards TE, Staker BL, Van Voorhis WC, Myler PJ, Stewart LJ.

Methods Enzymol. 2011;493:533-56. doi: 10.1016/B978-0-12-381274-2.00021-2.

5.

Multi-target parallel processing approach for gene-to-structure determination of the influenza polymerase PB2 subunit.

Armour BL, Barnes SR, Moen SO, Smith E, Raymond AC, Fairman JW, Stewart LJ, Staker BL, Begley DW, Edwards TE, Lorimer DD.

J Vis Exp. 2013 Jun 28;(76). doi: 10.3791/4225.

6.

Gene design, cloning and protein-expression methods for high-value targets at the Seattle Structural Genomics Center for Infectious Disease.

Raymond A, Haffner T, Ng N, Lorimer D, Staker B, Stewart L.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Sep 1;67(Pt 9):992-7. doi: 10.1107/S1744309111026698. Epub 2011 Aug 13.

7.

Combining functional and structural genomics to sample the essential Burkholderia structome.

Baugh L, Gallagher LA, Patrapuvich R, Clifton MC, Gardberg AS, Edwards TE, Armour B, Begley DW, Dieterich SH, Dranow DM, Abendroth J, Fairman JW, Fox D 3rd, Staker BL, Phan I, Gillespie A, Choi R, Nakazawa-Hewitt S, Nguyen MT, Napuli A, Barrett L, Buchko GW, Stacy R, Myler PJ, Stewart LJ, Manoil C, Van Voorhis WC.

PLoS One. 2013;8(1):e53851. doi: 10.1371/journal.pone.0053851. Epub 2013 Jan 31.

8.

Target selection for structural genomics: an overview.

Marsden RL, Orengo CA.

Methods Mol Biol. 2008;426:3-25. doi: 10.1007/978-1-60327-058-8_1. Review.

PMID:
18542854
9.

High-throughput protein production and purification at the Seattle Structural Genomics Center for Infectious Disease.

Bryan CM, Bhandari J, Napuli AJ, Leibly DJ, Choi R, Kelley A, Van Voorhis WC, Edwards TE, Stewart LJ.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Sep 1;67(Pt 9):1010-4. doi: 10.1107/S1744309111018367. Epub 2011 Aug 13.

10.

The tuberculosis structural genomics consortium: a structural genomics approach to drug discovery.

Musa TL, Ioerger TR, Sacchettini JC.

Adv Protein Chem Struct Biol. 2009;77:41-76. doi: 10.1016/S1876-1623(09)77003-8. Epub 2009 Nov 28. Review.

PMID:
20663481
11.

Benefits of structural genomics for drug discovery research.

Grabowski M, Chruszcz M, Zimmerman MD, Kirillova O, Minor W.

Infect Disord Drug Targets. 2009 Nov;9(5):459-74. Review.

12.

SAD phasing using iodide ions in a high-throughput structural genomics environment.

Abendroth J, Gardberg AS, Robinson JI, Christensen JS, Staker BL, Myler PJ, Stewart LJ, Edwards TE.

J Struct Funct Genomics. 2011 Jul;12(2):83-95. doi: 10.1007/s10969-011-9101-7. Epub 2011 Feb 27.

13.

NMR structure of an acyl-carrier protein from Borrelia burgdorferi.

Barnwal RP, Van Voorhis WC, Varani G.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 Sep 1;67(Pt 9):1137-40. doi: 10.1107/S1744309111004386. Epub 2011 Aug 13.

14.

A new asset for pathogen informatics--the Enteropathogen Resource Integration Center (ERIC), an NIAID Bioinformatics Resource Center for Biodefense and Emerging/Re-emerging Infectious Disease.

Greene JM, Plunkett G 3rd, Burland V, Glasner J, Cabot E, Anderson B, Neeno-Eckwall E, Qiu Y, Mau B, Rusch M, Liss P, Hampton T, Pot D, Shaker M, Shaull L, Shetty P, Shi C, Whitmore J, Wong M, Zaremba S, Blattner FR, Perna NT.

Adv Exp Med Biol. 2007;603:28-42.

PMID:
17966403
15.

[Development of antituberculous drugs: current status and future prospects].

Tomioka H, Namba K.

Kekkaku. 2006 Dec;81(12):753-74. Review. Japanese.

PMID:
17240921
16.

The scientific impact of the Structural Genomics Consortium: a protein family and ligand-centered approach to medically-relevant human proteins.

Gileadi O, Knapp S, Lee WH, Marsden BD, Müller S, Niesen FH, Kavanagh KL, Ball LJ, von Delft F, Doyle DA, Oppermann UC, Sundström M.

J Struct Funct Genomics. 2007 Sep;8(2-3):107-19. Epub 2007 Oct 12. Review.

17.

Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei.

Begley DW, Hartley RC, Davies DR, Edwards TE, Leonard JT, Abendroth J, Burris CA, Bhandari J, Myler PJ, Staker BL, Stewart LJ.

J Struct Funct Genomics. 2011 Jul;12(2):63-76. doi: 10.1007/s10969-011-9102-6. Epub 2011 Feb 26.

19.

Research resources for tuberculosis at the National Institute of Allergy and Infectious Diseases.

NIH, DMID TB program.

Tuberculosis (Edinb). 2013 Jan;93(1):6-11. doi: 10.1016/j.tube.2012.11.009. Epub 2013 Feb 4. Review.

PMID:
23385001
20.

Structural genomics of Mycobacterium tuberculosis: a preliminary report of progress at UCLA.

Goulding CW, Perry LJ, Anderson D, Sawaya MR, Cascio D, Apostol MI, Chan S, Parseghian A, Wang SS, Wu Y, Cassano V, Gill HS, Eisenberg D.

Biophys Chem. 2003 Sep;105(2-3):361-70.

PMID:
14499904
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